24 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (362 aa)
	Dbf4b.L	DBF4-type domain-containing protein. (784 aa)
	Wdhd1.L	Uncharacterized protein. (1127 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	mcm4	DNA helicase; Belongs to the MCM family. (858 aa)
	dbf4	Uncharacterized protein. (661 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Mcm4.S	DNA helicase; Belongs to the MCM family. (863 aa)
	Tipin.S	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (361 aa)
	ticrr	Treslin_N domain-containing protein. (1968 aa)
	mcm10	Mcm10 domain-containing protein. (860 aa)
	Lmnb3.L	Uncharacterized protein; Belongs to the intermediate filament family. (583 aa)
	Mrc1.L	C-type lectin domain-containing protein. (220 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	Lmnb2.S	Uncharacterized protein; Belongs to the intermediate filament family. (666 aa)
	Lmnb1.S	Uncharacterized protein; Belongs to the intermediate filament family. (583 aa)
	cdc45	Uncharacterized protein. (567 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	Clspn.S	Claspin. (1286 aa)
	LOC397912	LOC397912 protein; Belongs to the intermediate filament family. (623 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	lmnb1	Lmnb1-prov protein; Belongs to the intermediate filament family. (584 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Clspn.S	Dbf4b.L	F8WKR8	A0A1L8ESD2	Claspin.	DBF4-type domain-containing protein.	0.922
Clspn.S	Mcm4.S	F8WKR8	A0A1L8FYX1	Claspin.	DNA helicase; Belongs to the MCM family.	0.958
Clspn.S	Mrc1.L	F8WKR8	A0A1L8H4B7	Claspin.	C-type lectin domain-containing protein.	0.934
Clspn.S	Tipin.S	F8WKR8	A0A1L8GSF3	Claspin.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.999
Clspn.S	Wdhd1.L	F8WKR8	A0A1L8F9Z9	Claspin.	Uncharacterized protein.	0.990
Clspn.S	cdc45	F8WKR8	A0A1L8I0M4	Claspin.	Uncharacterized protein.	0.994
Clspn.S	chek1	F8WKR8	A0A1L8FFS1	Claspin.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.999
Clspn.S	chek1-2	F8WKR8	A0A1L8FL95	Claspin.	Protein kinase domain-containing protein.	0.999
Clspn.S	dbf4	F8WKR8	A0A1L8FVR6	Claspin.	Uncharacterized protein.	0.934
Clspn.S	mcm10	F8WKR8	A0A1L8GZD7	Claspin.	Mcm10 domain-containing protein.	0.984
Clspn.S	mcm4	F8WKR8	A0A1L8FSY2	Claspin.	DNA helicase; Belongs to the MCM family.	0.952
Clspn.S	rad9a	F8WKR8	Q7ZZU5	Claspin.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.978
Clspn.S	ticrr	F8WKR8	A0A1L8GSL4	Claspin.	Treslin_N domain-containing protein.	0.729
Clspn.S	tipin	F8WKR8	A0A1L8H168	Claspin.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.999
Clspn.S	topbp1	F8WKR8	A0A1L8FWJ6	Claspin.	Uncharacterized protein.	0.993
Dbf4b.L	Clspn.S	A0A1L8ESD2	F8WKR8	DBF4-type domain-containing protein.	Claspin.	0.922
Dbf4b.L	Mcm4.S	A0A1L8ESD2	A0A1L8FYX1	DBF4-type domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.995
Dbf4b.L	Mrc1.L	A0A1L8ESD2	A0A1L8H4B7	DBF4-type domain-containing protein.	C-type lectin domain-containing protein.	0.531
Dbf4b.L	Tipin.S	A0A1L8ESD2	A0A1L8GSF3	DBF4-type domain-containing protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.696
Dbf4b.L	Wdhd1.L	A0A1L8ESD2	A0A1L8F9Z9	DBF4-type domain-containing protein.	Uncharacterized protein.	0.876