STRINGSTRING
Cela2a.L Cela2a.L dkk1 dkk1 sumo2 sumo2 Kremen2.S Kremen2.S kremen2 kremen2 bhlhe23 bhlhe23 gntI gntI dkk1-2 dkk1-2 kremen1 kremen1 Kremen1.S Kremen1.S hgf-2 hgf-2 hgf hgf Lrp5.L Lrp5.L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cela2a.LPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
dkk1Dickkopf_N domain-containing protein. (263 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
Kremen2.SUncharacterized protein. (421 aa)
kremen2Uncharacterized protein. (420 aa)
bhlhe23BHLH domain-containing protein. (214 aa)
gntIGntI protein. (448 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
kremen1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
Kremen1.SKremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
hgf-2Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
hgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
Lrp5.LUncharacterized protein. (1517 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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