STRINGSTRING
ufd1-2 ufd1-2 H2B H2B Hus1 Hus1 rad9a rad9a gins4 gins4 mcm6.2 mcm6.2 A0A1L8ENU1 A0A1L8ENU1 Cdc6.L Cdc6.L Dbf4b.L Dbf4b.L Brca1.L Brca1.L chek1 chek1 chek1-2 chek1-2 A0A1L8FQ56 A0A1L8FQ56 A0A1L8FQA5 A0A1L8FQA5 cul2 cul2 mcm4 mcm4 cul2-2 cul2-2 dbf4 dbf4 topbp1 topbp1 mcm6 mcm6 Mcm4.S Mcm4.S H2B-2 H2B-2 pxdn pxdn A0A1L8G6R5 A0A1L8G6R5 A0A1L8G6S1 A0A1L8G6S1 A0A1L8G795 A0A1L8G795 pxdn-2 pxdn-2 rbx1 rbx1 atrip atrip Ctrl.L Ctrl.L Rad26 Rad26 xpc xpc skp1 skp1 skp1-2 skp1-2 cdc45 cdc45 Rad17.L Rad17.L A0A310TM08 A0A310TM08 A0A310U368 A0A310U368 Clspn.S Clspn.S ufd1 ufd1 nploc4 nploc4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ufd1-2MGC68571 protein. (307 aa)
H2BHistone H2B; Belongs to the histone H2B family. (126 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (282 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (221 aa)
mcm6.2DNA helicase; Belongs to the MCM family. (825 aa)
A0A1L8ENU1Uncharacterized protein; Belongs to the histone H2B family. (98 aa)
Cdc6.LCell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (645 aa)
Dbf4b.LDBF4-type domain-containing protein. (784 aa)
Brca1.LUncharacterized protein. (1582 aa)
chek1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
chek1-2Protein kinase domain-containing protein. (510 aa)
A0A1L8FQ56Histone H2B; Belongs to the histone H2B family. (126 aa)
A0A1L8FQA5Histone H2B; Belongs to the histone H2B family. (126 aa)
cul2CULLIN_2 domain-containing protein; Belongs to the cullin family. (766 aa)
mcm4DNA helicase; Belongs to the MCM family. (858 aa)
cul2-2CULLIN_2 domain-containing protein; Belongs to the cullin family. (745 aa)
dbf4Uncharacterized protein. (661 aa)
topbp1Uncharacterized protein. (1573 aa)
mcm6DNA helicase; Belongs to the MCM family. (821 aa)
Mcm4.SDNA helicase; Belongs to the MCM family. (863 aa)
H2B-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
pxdnUncharacterized protein. (1461 aa)
A0A1L8G6R5Histone H2B; Belongs to the histone H2B family. (347 aa)
A0A1L8G6S1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (238 aa)
A0A1L8G795Histone H2B; Belongs to the histone H2B family. (126 aa)
pxdn-2Uncharacterized protein. (1464 aa)
rbx1RING-type domain-containing protein. (120 aa)
atripUncharacterized protein. (801 aa)
Ctrl.LPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
Rad26Uncharacterized protein. (798 aa)
xpcUncharacterized protein. (1062 aa)
skp1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
skp1-2Uncharacterized protein; Belongs to the SKP1 family. (221 aa)
cdc45Uncharacterized protein. (567 aa)
Rad17.LUncharacterized protein. (674 aa)
A0A310TM08Histone H2B; Belongs to the histone H2B family. (126 aa)
A0A310U368Histone H2B; Belongs to the histone H2B family. (94 aa)
Clspn.SClaspin. (1286 aa)
ufd1Uncharacterized protein. (307 aa)
nploc4Npl4 protein. (610 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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