49 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tph1.L	Uncharacterized protein. (481 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	A0A1L8FEJ7	Suppressor of fused homolog. (474 aa)
	dvl1	Uncharacterized protein. (606 aa)
	egfr	Receptor protein-tyrosine kinase. (1208 aa)
	tshz1	Uncharacterized protein. (1093 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	egfr-2	Receptor protein-tyrosine kinase. (1210 aa)
	Tshz1.L	Uncharacterized protein. (1077 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	Zic1.S	Uncharacterized protein. (443 aa)
	Pax3.S	Uncharacterized protein. (592 aa)
	gata4	Uncharacterized protein. (392 aa)
	tgfb2-2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	Ptk7.L	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
	Pax3.L	Uncharacterized protein. (590 aa)
	tshz3	Uncharacterized protein. (1072 aa)
	wls	Uncharacterized protein. (541 aa)
	Myod1.L	Myogenic factor. (289 aa)
	tshz3-2	Uncharacterized protein. (1075 aa)
	Wls.L	Uncharacterized protein. (541 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	tshb	Cys_knot domain-containing protein. (141 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	gli1	Uncharacterized protein. (1361 aa)
	tshb-2	Cys_knot domain-containing protein. (141 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Gli1.L	Uncharacterized protein. (1362 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	fgfrl1	Uncharacterized protein. (490 aa)
	fst	Uncharacterized protein. (339 aa)
	fst-2	Uncharacterized protein. (341 aa)
	lhx1	Homeobox protein. (403 aa)
	zic5-2	Zic family member 5. (515 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	myod1-a	Myoblast determination protein 1 homolog A; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (289 aa)
	sp5	MGC131081 protein. (375 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	gata4-2	MGC81427 protein. (394 aa)
	chd4	B230399n07 protein. (1893 aa)
	Tshz2.S	Uncharacterized protein. (1257 aa)
	notum	Uncharacterized protein. (488 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Tshz2.L	Uncharacterized protein. (1035 aa)
	Notum.L	Uncharacterized protein. (386 aa)
	A0A1L8EX74	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EX74	Wnt1.L	A0A1L8EX74	A0A1L8HHR8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.848
A0A1L8EX74	ctnnb1	A0A1L8EX74	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.511
A0A1L8EX74	dvl1	A0A1L8EX74	A0A1L8FM70	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.801
A0A1L8EX74	wnt1	A0A1L8EX74	A0A1L8H9S8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.848
A0A1L8EX74	wnt11	A0A1L8EX74	A0A1L8HJX1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.841
A0A1L8EX74	wnt11b	A0A1L8EX74	A0A1L8F6W4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.840
A0A1L8FEJ7	Gli1.L	A0A1L8FEJ7	A0A1L8HI29	Suppressor of fused homolog.	Uncharacterized protein.	0.999
A0A1L8FEJ7	Shh.L	A0A1L8FEJ7	A0A1L8FV87	Suppressor of fused homolog.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.786
A0A1L8FEJ7	ctnnb1	A0A1L8FEJ7	Q63ZT4	Suppressor of fused homolog.	Beta-catenin protein.	0.444
A0A1L8FEJ7	gli1	A0A1L8FEJ7	A0A1L8HA22	Suppressor of fused homolog.	Uncharacterized protein.	0.999
Fzd8.L	Shh.L	A0A1L8FVD0	A0A1L8FV87	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.493
Fzd8.L	Wls.L	A0A1L8FVD0	A0A1L8GLU8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.419
Fzd8.L	Wnt1.L	A0A1L8FVD0	A0A1L8HHR8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.912
Fzd8.L	ctnnb1	A0A1L8FVD0	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.826
Fzd8.L	dvl1	A0A1L8FVD0	A0A1L8FM70	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.867
Fzd8.L	wls	A0A1L8FVD0	A0A1L8GFD4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.419
Fzd8.L	wnt1	A0A1L8FVD0	A0A1L8H9S8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.912
Fzd8.L	wnt11	A0A1L8FVD0	A0A1L8HJX1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.911
Fzd8.L	wnt11b	A0A1L8FVD0	A0A1L8F6W4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.920
Gli1.L	A0A1L8FEJ7	A0A1L8HI29	A0A1L8FEJ7	Uncharacterized protein.	Suppressor of fused homolog.	0.999