28 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	Zic2.S	Uncharacterized protein. (497 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	lep	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
	nap1l1-2	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (393 aa)
	fgf23.1-2	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (244 aa)
	Fgf23.2.L	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (256 aa)
	nap1l1	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (547 aa)
	fgf23.1	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (244 aa)
	Fgf23.2.S	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (256 aa)
	maf-2	BZIP domain-containing protein; Belongs to the bZIP family. (351 aa)
	maf	BZIP domain-containing protein; Belongs to the bZIP family. (344 aa)
	sobp-2	Uncharacterized protein. (863 aa)
	bcl2l11-2	Uncharacterized protein. (194 aa)
	sobp	Uncharacterized protein. (868 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	bcl2l11	Uncharacterized protein. (194 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	Fn1.S	Uncharacterized protein. (2480 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (560 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)
	rhoa	MGC64296 protein. (193 aa)
	matn1	MGC64509 protein. (490 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (560 aa)
	lep-2	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	Zic2.L	Uncharacterized protein. (502 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fn1.S	rhoa	A0A1L8EPN8	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.589
Stmn1.S	stmn1	A0A1L8H795	A0A1L8HEF1	Uncharacterized protein.	Stathmin; Belongs to the stathmin family.	0.900
bcl2l11	bcl2l11-2	A0A1L8G1Y7	A0A1L8G7D9	Uncharacterized protein.	Uncharacterized protein.	0.900
bcl2l11-2	bcl2l11	A0A1L8G7D9	A0A1L8G1Y7	Uncharacterized protein.	Uncharacterized protein.	0.900
lep	lep-2	A0A1L8GZQ3	Q563I5	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.900
lep-2	lep	Q563I5	A0A1L8GZQ3	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.900
matn1	sobp	Q7SYT5	A0A1L8G2Z1	MGC64509 protein.	Uncharacterized protein.	0.524
matn1	sobp-2	Q7SYT5	A0A1L8G9H9	MGC64509 protein.	Uncharacterized protein.	0.524
nap1l1	prkaa1	A0A1L8GUC2	Q5U5E3	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Non-specific serine/threonine protein kinase.	0.416
nap1l1	prkaa2	A0A1L8GUC2	Q8UVW8	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Non-specific serine/threonine protein kinase.	0.416
nap1l1-2	prkaa1	A0A1L8GYL4	Q5U5E3	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Non-specific serine/threonine protein kinase.	0.416
nap1l1-2	prkaa2	A0A1L8GYL4	Q8UVW8	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	Non-specific serine/threonine protein kinase.	0.416
prkaa1	nap1l1	Q5U5E3	A0A1L8GUC2	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	0.416
prkaa1	nap1l1-2	Q5U5E3	A0A1L8GYL4	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	0.416
prkaa2	nap1l1	Q8UVW8	A0A1L8GUC2	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	0.416
prkaa2	nap1l1-2	Q8UVW8	A0A1L8GYL4	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.	0.416
rhoa	Fn1.S	Q7SZA9	A0A1L8EPN8	MGC64296 protein.	Uncharacterized protein.	0.589
rhoa	stmn2	Q7SZA9	A0A1L8FZA7	MGC64296 protein.	Stathmin; Belongs to the stathmin family.	0.522
rhoa	stmn2-2	Q7SZA9	Q6DJD4	MGC64296 protein.	Stathmin; Belongs to the stathmin family.	0.538
sobp	matn1	A0A1L8G2Z1	Q7SYT5	Uncharacterized protein.	MGC64509 protein.	0.524