25 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tp53.L	P53 domain-containing protein. (137 aa)
	map2k1-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
	ccne1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	oma1	Peptidase_M48 domain-containing protein. (476 aa)
	Ccne1.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	gpr12	GPRx; Belongs to the G-protein coupled receptor 1 family. (340 aa)
	cdc25b	Cdc25B phosphatase. (562 aa)
	LOC398006	Tyrosine-protein kinase receptor. (1362 aa)
	src	Tyrosine-protein kinase. (532 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	Mastl.L	Uncharacterized protein. (887 aa)
	plk1	Serine/threonine-protein kinase PLK. (598 aa)
	cdk1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
	Gnas.S	Uncharacterized protein. (217 aa)
	Plk1.S	Serine/threonine-protein kinase PLK. (598 aa)
	Cdk1.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	gpr1-2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (351 aa)
	Mapk1.L	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	ereg-2	Uncharacterized protein. (156 aa)
	areg-2	EGF-like domain-containing protein. (228 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	areg	EGF-like domain-containing protein. (226 aa)
	ereg	Uncharacterized protein. (156 aa)
	Cdk2.S	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccne1.S	Cdk1.L	A0A1L8GF58	A0A1L8FIT4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.993
Ccne1.S	Cdk2.S	A0A1L8GF58	A0A1L8H9N1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.999
Ccne1.S	Plk1.S	A0A1L8GF58	A0A1L8EQN7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Serine/threonine-protein kinase PLK.	0.594
Ccne1.S	Tp53.L	A0A1L8GF58	A0A1L8H4M6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	P53 domain-containing protein.	0.837
Ccne1.S	cdc25b	A0A1L8GF58	B2DCQ5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cdc25B phosphatase.	0.810
Ccne1.S	cdk1	A0A1L8GF58	A0A1L8FE96	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.993
Ccne1.S	plk1	A0A1L8GF58	A0A1L8EYC7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Serine/threonine-protein kinase PLK.	0.660
Ccne1.S	src	A0A1L8GF58	Q2TAR1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Tyrosine-protein kinase.	0.488
Cdk1.L	Ccne1.S	A0A1L8FIT4	A0A1L8GF58	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.993
Cdk1.L	Cdk2.S	A0A1L8FIT4	A0A1L8H9N1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.895
Cdk1.L	Mapk1.L	A0A1L8FIT4	A0A1L8I0W2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.640
Cdk1.L	Mastl.L	A0A1L8FIT4	A0A1L8FVG9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.632
Cdk1.L	Plk1.S	A0A1L8FIT4	A0A1L8EQN7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase PLK.	0.984
Cdk1.L	Tp53.L	A0A1L8FIT4	A0A1L8H4M6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	P53 domain-containing protein.	0.904
Cdk1.L	ccne1	A0A1L8FIT4	A0A1L8GL65	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.993
Cdk1.L	cdc25b	A0A1L8FIT4	B2DCQ5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cdc25B phosphatase.	0.997
Cdk1.L	cdk1	A0A1L8FIT4	A0A1L8FE96	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.900
Cdk1.L	map2k1-2	A0A1L8FIT4	A0A1L8H157	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.698
Cdk1.L	mapk1	A0A1L8FIT4	A0A1L8HQD8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.642
Cdk1.L	plk1	A0A1L8FIT4	A0A1L8EYC7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase PLK.	0.984