30 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2B	Histone H2B; Belongs to the histone H2B family. (126 aa)
	Plk1.S	Serine/threonine-protein kinase PLK. (598 aa)
	aurka	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (407 aa)
	plk1	Serine/threonine-protein kinase PLK. (598 aa)
	cdk1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
	Cdk1.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	pard3	Uncharacterized protein. (1369 aa)
	pard3-2	Uncharacterized protein. (1332 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	H2B-2	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	Incenp.S	Uncharacterized protein. (892 aa)
	Cdca9.S	Nbl1_Borealin_N domain-containing protein. (296 aa)
	Incenp.L	Uncharacterized protein. (975 aa)
	npm2	Nucleoplasmin domain-containing protein. (196 aa)
	kif20a	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (907 aa)
	aurkb	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	cdca8	Nbl1_Borealin_N domain-containing protein. (275 aa)
	Birc5.1.L	Uncharacterized protein. (160 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	cdca8-2	Nbl1_Borealin_N domain-containing protein. (280 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	src	Tyrosine-protein kinase. (532 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	npm2-2	Npm-A protein. (200 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alb.S	Cdk1.L	A0A1L8HMG9	A0A1L8FIT4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.457
Alb.S	H2B	A0A1L8HMG9	Q92130	Uncharacterized protein.	Histone H2B; Belongs to the histone H2B family.	0.670
Alb.S	H2B-2	A0A1L8HMG9	A0A1L8G0X3	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.675
Alb.S	actl6a	A0A1L8HMG9	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.882
Alb.S	cdk1	A0A1L8HMG9	A0A1L8FE96	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.457
Alb.S	plk1	A0A1L8HMG9	A0A1L8EYC7	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.422
Alb.S	src	A0A1L8HMG9	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.409
Birc5.1.L	Cdk1.L	A0A1L8HA18	A0A1L8FIT4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.904
Birc5.1.L	Incenp.L	A0A1L8HA18	A0A1L8GJ41	Uncharacterized protein.	Uncharacterized protein.	0.998
Birc5.1.L	Incenp.S	A0A1L8HA18	A0A1L8GD76	Uncharacterized protein.	Uncharacterized protein.	0.996
Birc5.1.L	Plk1.S	A0A1L8HA18	A0A1L8EQN7	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.879
Birc5.1.L	aurka	A0A1L8HA18	A0A1L8ESU8	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.926
Birc5.1.L	aurkb	A0A1L8HA18	A0A1L8H3C5	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.953
Birc5.1.L	cdca8	A0A1L8HA18	A0A1L8H7S8	Uncharacterized protein.	Nbl1_Borealin_N domain-containing protein.	0.992
Birc5.1.L	cdca8-2	A0A1L8HA18	A0A1L8HFF1	Uncharacterized protein.	Nbl1_Borealin_N domain-containing protein.	0.992
Birc5.1.L	cdk1	A0A1L8HA18	A0A1L8FE96	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.903
Birc5.1.L	kif20a	A0A1L8HA18	A0A1L8GY32	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.610
Birc5.1.L	plk1	A0A1L8HA18	A0A1L8EYC7	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.879
Birc5.1.L	stmn1	A0A1L8HA18	A0A1L8HEF1	Uncharacterized protein.	Stathmin; Belongs to the stathmin family.	0.605
Cdca9.S	Incenp.L	A0A1L8GF65	A0A1L8GJ41	Nbl1_Borealin_N domain-containing protein.	Uncharacterized protein.	0.972