38 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Vegfc.S	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (407 aa)
	Nfatc2.S	RHD domain-containing protein. (884 aa)
	Ctla4.S	IGv domain-containing protein. (242 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	nfatc2	RHD domain-containing protein. (896 aa)
	atf2	Uncharacterized protein. (486 aa)
	Ctla4.L	IG domain-containing protein. (209 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	Rock1.S	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
	Rock1.L	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	rock2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1399 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Rock2.L	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	nfatc3	RHD domain-containing protein. (885 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	Rho.L	Rhodopsin. (459 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	A0A1L8GUI6	Uncharacterized protein. (183 aa)
	Ckap4.L	Uncharacterized protein. (548 aa)
	ifng	Uncharacterized protein. (182 aa)
	A0A1L8H4P9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (469 aa)
	rnf43	RING-type domain-containing protein. (664 aa)
	Aldh3a2.L	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)
	Kremen1.S	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
	Znrf3.S	RING-type domain-containing protein. (848 aa)
	vegfc	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (402 aa)
	aldh3b1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
	kremen1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
	znrf3	RING-type domain-containing protein. (854 aa)
	nf-at	Nuclear factor of activated T-cell. (884 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	rac1	MGC114731 protein. (192 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	aldh3a2	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)
	rhoa	MGC64296 protein. (193 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GUI6	Ctla4.L	A0A1L8GUI6	A0A1L8EWT4	Uncharacterized protein.	IG domain-containing protein.	0.568
A0A1L8GUI6	Ctla4.S	A0A1L8GUI6	A0A1L8EPS6	Uncharacterized protein.	IGv domain-containing protein.	0.568
A0A1L8GUI6	Jun.L	A0A1L8GUI6	A0A1L8GLZ4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.447
A0A1L8GUI6	Nfatc2.S	A0A1L8GUI6	A0A1L8ELF6	Uncharacterized protein.	RHD domain-containing protein.	0.451
A0A1L8GUI6	c-Jun	A0A1L8GUI6	Q9PVZ1	Uncharacterized protein.	C-Jun protein; Belongs to the bZIP family.	0.447
A0A1L8GUI6	ctnnb1	A0A1L8GUI6	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.448
A0A1L8GUI6	ifng	A0A1L8GUI6	A0A1L8GYI9	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8GUI6	nfatc2	A0A1L8GUI6	A0A1L8ESQ8	Uncharacterized protein.	RHD domain-containing protein.	0.451
A0A1L8H4P9	aldh3b1	A0A1L8H4P9	A0A1L8I0K0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.902
A0A1L8H4P9	ctnnb1	A0A1L8H4P9	Q63ZT4	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Beta-catenin protein.	0.474
Axin1.S	Jun.L	A0A1L8ER48	A0A1L8GLZ4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.710
Axin1.S	Lrp5.L	A0A1L8ER48	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.998
Axin1.S	Nfatc2.S	A0A1L8ER48	A0A1L8ELF6	Uncharacterized protein.	RHD domain-containing protein.	0.479
Axin1.S	Rho.L	A0A1L8ER48	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.437
Axin1.S	Rock1.L	A0A1L8ER48	A0A1L8FYP1	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.407
Axin1.S	Rock1.S	A0A1L8ER48	A0A1L8FSV4	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.407
Axin1.S	Rock2.L	A0A1L8ER48	A0A1L8GBJ7	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.425
Axin1.S	Znrf3.S	A0A1L8ER48	A0A1L8HQY2	Uncharacterized protein.	RING-type domain-containing protein.	0.668
Axin1.S	c-Jun	A0A1L8ER48	Q9PVZ1	Uncharacterized protein.	C-Jun protein; Belongs to the bZIP family.	0.710
Axin1.S	ctnnb1	A0A1L8ER48	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.999