20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	calml4-2	Uncharacterized protein. (152 aa)
	calml4	Uncharacterized protein. (153 aa)
	patj	Uncharacterized protein. (1796 aa)
	calm1	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	Glb1l.L	Beta-galactosidase. (645 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	glb1l2	Beta-galactosidase. (634 aa)
	Lgals4.L	Galectin. (319 aa)
	Glb1l2.S	Beta-galactosidase. (616 aa)
	notch1	Uncharacterized protein. (2521 aa)
	lgals4.2	Galectin. (319 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	glb1	Uncharacterized protein; Belongs to the glycosyl hydrolase 35 family. (642 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	pard6b	Uncharacterized protein. (377 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	cask-2	Cask-prov protein; Belongs to the MAGUK family. (920 aa)
	src	Tyrosine-protein kinase. (532 aa)
	Yap1.L	Uncharacterized protein. (459 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (920 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Glb1l.L	glb1	A0A1L8FWQ8	A0A1L8EVM8	Beta-galactosidase.	Uncharacterized protein; Belongs to the glycosyl hydrolase 35 family.	0.902
Lgals4.L	Notch1.S	A0A1L8F924	A0A1L8F124	Galectin.	Uncharacterized protein.	0.671
Lgals4.L	Shh.L	A0A1L8F924	A0A1L8FV87	Galectin.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.449
Lgals4.L	notch1	A0A1L8F924	A0A1L8F627	Galectin.	Uncharacterized protein.	0.649
Lgals4.L	patj	A0A1L8F924	A0A1L8GLZ0	Galectin.	Uncharacterized protein.	0.443
Llgl1.S	pard6b	A0A1L8ER29	A0A1L8ELH2	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.956
Llgl1.S	pard6b-2	A0A1L8ER29	A0A1L8ESP6	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.956
Llgl1.S	patj	A0A1L8ER29	A0A1L8GLZ0	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.887
Notch1.S	Lgals4.L	A0A1L8F124	A0A1L8F924	Uncharacterized protein.	Galectin.	0.671
Notch1.S	Shh.L	A0A1L8F124	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.936
Notch1.S	Yap1.L	A0A1L8F124	A0A1L8HJ61	Uncharacterized protein.	Uncharacterized protein.	0.523
Notch1.S	lgals4.2	A0A1L8F124	A0A1L8F404	Uncharacterized protein.	Galectin.	0.671
Notch1.S	src	A0A1L8F124	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.551
Shh.L	Lgals4.L	A0A1L8FV87	A0A1L8F924	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Galectin.	0.449
Shh.L	Notch1.S	A0A1L8FV87	A0A1L8F124	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.936
Shh.L	Yap1.L	A0A1L8FV87	A0A1L8HJ61	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.431
Shh.L	calm1	A0A1L8FV87	A0A1L8G5X8	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein; Belongs to the calmodulin family.	0.405
Shh.L	lgals4.2	A0A1L8FV87	A0A1L8F404	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Galectin.	0.441
Shh.L	notch1	A0A1L8FV87	A0A1L8F627	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.935
Yap1.L	Notch1.S	A0A1L8HJ61	A0A1L8F124	Uncharacterized protein.	Uncharacterized protein.	0.523