34 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mef2c-2	MADS-box domain-containing protein. (464 aa)
	ddx18	RNA helicase. (641 aa)
	pecam1	Uncharacterized protein. (684 aa)
	Ddx18.L	RNA helicase. (638 aa)
	Itgb2.S	Integrin beta. (769 aa)
	Cfp.L	Uncharacterized protein. (447 aa)
	Ddx31.L	RNA helicase. (462 aa)
	Sox17a.S	Uncharacterized protein. (377 aa)
	sox17b.1	Uncharacterized protein. (373 aa)
	ulk4	Protein kinase domain-containing protein. (1265 aa)
	sox17b.1-2	Uncharacterized protein. (373 aa)
	H2B-2	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
	tbxt	Uncharacterized protein. (432 aa)
	Foxa2.L	Fork-head domain-containing protein. (434 aa)
	cdh5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
	cdh5-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
	mov10l1	AAA domain-containing protein. (1247 aa)
	mpo	Uncharacterized protein. (725 aa)
	A0A1L8HAU8	RNA helicase. (784 aa)
	mpo-2	Uncharacterized protein. (725 aa)
	kdr	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1326 aa)
	Vegfc.S	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (407 aa)
	Aplnr.S	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	ddx55	RNA helicase. (594 aa)
	mef2c	MADS-box domain-containing protein. (464 aa)
	vegfc	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (402 aa)
	Pitx2.S	Homeobox protein. (326 aa)
	aplnr	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	H2B	Histone H2B; Belongs to the histone H2B family. (126 aa)
	tbxt-2	MGC81453 protein. (432 aa)
	pitx2	Homeobox protein. (323 aa)
	pecam1-2	Platelet endothelial cell adhesion molecule. (727 aa)
	hand1	Heart and neural crest derivatives expressed 1. (197 aa)
	apln	Apln-b protein. (76 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8HAU8	Ddx18.L	A0A1L8HAU8	A0A1L8EV49	RNA helicase.	RNA helicase.	0.991
A0A1L8HAU8	Ddx31.L	A0A1L8HAU8	A0A1L8F6D3	RNA helicase.	RNA helicase.	0.917
A0A1L8HAU8	ddx18	A0A1L8HAU8	A0A1L8ENF7	RNA helicase.	RNA helicase.	0.991
A0A1L8HAU8	ddx55	A0A1L8HAU8	A0A1L8HQL1	RNA helicase.	RNA helicase.	0.866
A0A1L8HAU8	mov10l1	A0A1L8HAU8	A0A1L8GZ04	RNA helicase.	AAA domain-containing protein.	0.641
Aplnr.S	apln	A0A1L8HPT3	A1XP38	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Apln-b protein.	0.999
Aplnr.S	aplnr	A0A1L8HPT3	A0A1L8HZT2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.900
Aplnr.S	cdh5	A0A1L8HPT3	A0A1L8GEW5	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.564
Aplnr.S	cdh5-2	A0A1L8HPT3	A0A1L8GKR1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.564
Aplnr.S	kdr	A0A1L8HPT3	A0A1L8HLA0	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.589
Aplnr.S	pecam1	A0A1L8HPT3	A0A1L8ENK4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.420
Aplnr.S	pecam1-2	A0A1L8HPT3	Q5W5X8	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Platelet endothelial cell adhesion molecule.	0.400
Aplnr.S	sox17b.1	A0A1L8HPT3	A0A1L8FT40	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.428
Ddx18.L	A0A1L8HAU8	A0A1L8EV49	A0A1L8HAU8	RNA helicase.	RNA helicase.	0.991
Ddx18.L	Ddx31.L	A0A1L8EV49	A0A1L8F6D3	RNA helicase.	RNA helicase.	0.896
Ddx18.L	ddx55	A0A1L8EV49	A0A1L8HQL1	RNA helicase.	RNA helicase.	0.954
Ddx18.L	mov10l1	A0A1L8EV49	A0A1L8GZ04	RNA helicase.	AAA domain-containing protein.	0.494
Ddx31.L	A0A1L8HAU8	A0A1L8F6D3	A0A1L8HAU8	RNA helicase.	RNA helicase.	0.917
Ddx31.L	Ddx18.L	A0A1L8F6D3	A0A1L8EV49	RNA helicase.	RNA helicase.	0.896
Ddx31.L	ddx18	A0A1L8F6D3	A0A1L8ENF7	RNA helicase.	RNA helicase.	0.896