43 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mcam	Uncharacterized protein. (618 aa)
	ncam1	Uncharacterized protein. (1121 aa)
	mapk10	Mitogen-activated protein kinase. (426 aa)
	vangl2-2	Vang-like protein. (521 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	vangl2	Vang-like protein. (521 aa)
	A0A1L8F270	FERM domain-containing protein. (580 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	NUBP1	Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (369 aa)
	nfatc2	RHD domain-containing protein. (896 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	nubp1	Cytosolic Fe-S cluster assembly factor nubp1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (315 aa)
	pard6b	Uncharacterized protein. (377 aa)
	Nfatc2.S	RHD domain-containing protein. (884 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	myog	Myogenin U1. (235 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	myod1-a	Myoblast determination protein 1 homolog A; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (289 aa)
	sox9-a	Sex determining region Y-box 9. (477 aa)
	nf-at	Nuclear factor of activated T-cell. (884 aa)
	Mcam.S	Uncharacterized protein. (632 aa)
	Nf2.L	FERM domain-containing protein. (583 aa)
	Nf2.S	FERM domain-containing protein. (584 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	arhgef7-2	Uncharacterized protein. (802 aa)
	A0A1L8HG68	FERM domain-containing protein. (638 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	arhgef7	Uncharacterized protein. (818 aa)
	Myog.S	BHLH domain-containing protein. (236 aa)
	nfatc3	RHD domain-containing protein. (885 aa)
	Fgf4.L	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	col10a1	C1q domain-containing protein. (668 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	ncam1-2	Uncharacterized protein. (1108 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYQ3	Prkci.L	A0A1L8EYQ3	A0A1L8GAK2	LLGL domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.992
A0A1L8EYQ3	actl6a	A0A1L8EYQ3	Q7ZYI5	LLGL domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.439
A0A1L8EYQ3	pard6b	A0A1L8EYQ3	A0A1L8ELH2	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	pard6b-2	A0A1L8EYQ3	A0A1L8ESP6	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8F270	Prkci.L	A0A1L8F270	A0A1L8GAK2	FERM domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.412
A0A1L8F270	actl6a	A0A1L8F270	Q7ZYI5	FERM domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.978
A0A1L8F270	ctnnb1	A0A1L8F270	Q63ZT4	FERM domain-containing protein.	Beta-catenin protein.	0.447
A0A1L8HG68	Mcam.S	A0A1L8HG68	A0A310U8B7	FERM domain-containing protein.	Uncharacterized protein.	0.456
A0A1L8HG68	Nf2.L	A0A1L8HG68	A0A1L8HZV7	FERM domain-containing protein.	FERM domain-containing protein.	0.903
A0A1L8HG68	Nf2.S	A0A1L8HG68	A0A1L8HPZ9	FERM domain-containing protein.	FERM domain-containing protein.	0.903
A0A1L8HG68	actl6a	A0A1L8HG68	Q7ZYI5	FERM domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.400
A0A1L8HG68	ctnnb1	A0A1L8HG68	Q63ZT4	FERM domain-containing protein.	Beta-catenin protein.	0.425
A0A1L8HG68	pard6b	A0A1L8HG68	A0A1L8ELH2	FERM domain-containing protein.	Uncharacterized protein.	0.617
A0A1L8HG68	pard6b-2	A0A1L8HG68	A0A1L8ESP6	FERM domain-containing protein.	Uncharacterized protein.	0.617
Bmp2.L	Fgf4.L	A0A1L8G5P4	A0A1L8GIU8	TGF_BETA_2 domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
Bmp2.L	Gapdh.S	A0A1L8G5P4	Q7ZY52	TGF_BETA_2 domain-containing protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.416
Bmp2.L	Wnt1.L	A0A1L8G5P4	A0A1L8HHR8	TGF_BETA_2 domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.518
Bmp2.L	bmp2	A0A1L8G5P4	A0A1L8G1N2	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.900
Bmp2.L	col10a1	A0A1L8G5P4	A0A1L8G358	TGF_BETA_2 domain-containing protein.	C1q domain-containing protein.	0.427
Bmp2.L	ctnnb1	A0A1L8G5P4	Q63ZT4	TGF_BETA_2 domain-containing protein.	Beta-catenin protein.	0.775