20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	dand5	CTCK domain-containing protein. (219 aa)
	myl7	Uncharacterized protein. (172 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	A0A1L8GA54	Uncharacterized protein. (882 aa)
	Thpo.L	Uncharacterized protein. (191 aa)
	A0A1L8GA23	Chordin; Belongs to the chordin family. (940 aa)
	Chrd.1.S	Chordin; Belongs to the chordin family. (941 aa)
	Thpo.S	Uncharacterized protein. (172 aa)
	foxh1	Fork-head domain-containing protein. (518 aa)
	sox17b.1-2	Uncharacterized protein. (373 aa)
	Evx1.L	Homeobox domain-containing protein. (484 aa)
	sox17b.1	Uncharacterized protein. (373 aa)
	Sox17a.S	Uncharacterized protein. (377 aa)
	Evx1.S	Homeobox domain-containing protein. (464 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	gsc	Homeobox domain-containing protein. (294 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (590 aa)
	Gsc.S	Homeobox domain-containing protein. (243 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GA23	A0A1L8GA54	A0A1L8GA23	A0A1L8GA54	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.900
A0A1L8GA23	Chrd.1.S	A0A1L8GA23	A0A1L8G404	Chordin; Belongs to the chordin family.	Chordin; Belongs to the chordin family.	0.900
A0A1L8GA23	Evx1.L	A0A1L8GA23	A0A1L8FW80	Chordin; Belongs to the chordin family.	Homeobox domain-containing protein.	0.694
A0A1L8GA23	Evx1.S	A0A1L8GA23	A0A1L8FRA2	Chordin; Belongs to the chordin family.	Homeobox domain-containing protein.	0.785
A0A1L8GA23	Gsc.S	A0A1L8GA23	A0A1L8F0K5	Chordin; Belongs to the chordin family.	Homeobox domain-containing protein.	0.957
A0A1L8GA23	Sox17a.S	A0A1L8GA23	A0A1L8FT01	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.565
A0A1L8GA23	gsc	A0A1L8GA23	A0A1L8F9K8	Chordin; Belongs to the chordin family.	Homeobox domain-containing protein.	0.957
A0A1L8GA23	sox17b.1	A0A1L8GA23	A0A1L8FT40	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.546
A0A1L8GA23	sox17b.1-2	A0A1L8GA23	A0A1L8FZ03	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.489
A0A1L8GA54	A0A1L8GA23	A0A1L8GA54	A0A1L8GA23	Uncharacterized protein.	Chordin; Belongs to the chordin family.	0.900
A0A1L8GA54	Chrd.1.S	A0A1L8GA54	A0A1L8G404	Uncharacterized protein.	Chordin; Belongs to the chordin family.	0.900
A0A1L8GA54	Evx1.L	A0A1L8GA54	A0A1L8FW80	Uncharacterized protein.	Homeobox domain-containing protein.	0.694
A0A1L8GA54	Evx1.S	A0A1L8GA54	A0A1L8FRA2	Uncharacterized protein.	Homeobox domain-containing protein.	0.785
A0A1L8GA54	Gsc.S	A0A1L8GA54	A0A1L8F0K5	Uncharacterized protein.	Homeobox domain-containing protein.	0.957
A0A1L8GA54	Sox17a.S	A0A1L8GA54	A0A1L8FT01	Uncharacterized protein.	Uncharacterized protein.	0.565
A0A1L8GA54	gsc	A0A1L8GA54	A0A1L8F9K8	Uncharacterized protein.	Homeobox domain-containing protein.	0.957
A0A1L8GA54	sox17b.1	A0A1L8GA54	A0A1L8FT40	Uncharacterized protein.	Uncharacterized protein.	0.546
A0A1L8GA54	sox17b.1-2	A0A1L8GA54	A0A1L8FZ03	Uncharacterized protein.	Uncharacterized protein.	0.489
Chrd.1.S	A0A1L8GA23	A0A1L8G404	A0A1L8GA23	Chordin; Belongs to the chordin family.	Chordin; Belongs to the chordin family.	0.900
Chrd.1.S	A0A1L8GA54	A0A1L8G404	A0A1L8GA54	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.900