STRINGSTRING
rangap1 rangap1 H2B H2B Sumo1.S Sumo1.S Sumo1.L Sumo1.L taz taz Drosha.S Drosha.S H2B-2 H2B-2 pxdn pxdn kat14 kat14 pxdn-2 pxdn-2 Rangap1.S Rangap1.S uba2 uba2 plscr3 plscr3 tuba1b tuba1b tuba1b-2 tuba1b-2 Anxa5.L Anxa5.L A0A310U5D8 A0A310U5D8 anxa5 anxa5 myc myc arpc1b-a arpc1b-a sumo2 sumo2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rangap1Rangap1-prov protein. (584 aa)
H2BHistone H2B; Belongs to the histone H2B family. (126 aa)
Sumo1.SUbiquitin-like domain-containing protein. (141 aa)
Sumo1.LUbiquitin-like domain-containing protein. (148 aa)
tazTafazzin family protein; Belongs to the taffazin family. (262 aa)
Drosha.SUncharacterized protein. (1308 aa)
H2B-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
pxdnUncharacterized protein. (1461 aa)
kat14N-acetyltransferase domain-containing protein. (776 aa)
pxdn-2Uncharacterized protein. (1464 aa)
Rangap1.SRanGAP1_C domain-containing protein. (583 aa)
uba2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa)
plscr3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (296 aa)
tuba1bTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
tuba1b-2Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
Anxa5.LAnnexin. (323 aa)
A0A310U5D8Rad60-SLD domain-containing protein. (67 aa)
anxa5Annexin. (323 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
arpc1b-aActin-related protein 2/3 complex subunit 1B-A; Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity). The Arp2/3 complex promotes homologous recombination (HR) repair [...] (369 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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