STRINGSTRING
Cdk2.S Cdk2.S rad9b rad9b Rad17.L Rad17.L A0A310TTQ1 A0A310TTQ1 rad9a rad9a myc myc Clspn.S Clspn.S h3f3b h3f3b Orc2.S Orc2.S A0A1L8EY07 A0A1L8EY07 plk1 plk1 chek1 chek1 chek1-2 chek1-2 topbp1 topbp1 hist2h3c hist2h3c Rel.L Rel.L Ccne1.S Ccne1.S ccne1 ccne1 Chek2.L Chek2.L pcna pcna Hus1 Hus1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cdk2.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
rad9bCell cycle checkpoint control protein; Belongs to the rad9 family. (483 aa)
Rad17.LUncharacterized protein. (674 aa)
A0A310TTQ1Histone H3; Belongs to the histone H3 family. (136 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
Clspn.SClaspin. (1286 aa)
h3f3bHistone H3; Belongs to the histone H3 family. (136 aa)
Orc2.SUncharacterized protein. (558 aa)
A0A1L8EY07Histone H3; Belongs to the histone H3 family. (120 aa)
plk1Serine/threonine-protein kinase PLK. (598 aa)
chek1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
chek1-2Protein kinase domain-containing protein. (510 aa)
topbp1Uncharacterized protein. (1573 aa)
hist2h3cHistone H3; Belongs to the histone H3 family. (136 aa)
Rel.LRHD domain-containing protein. (583 aa)
Ccne1.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
ccne1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
Chek2.LUncharacterized protein. (392 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (282 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
Server load: low (14%) [HD]