18 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prkaca	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	Rgs6.S	Uncharacterized protein. (394 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	Arr3.L	Arrestin_C domain-containing protein. (387 aa)
	tfap2a	TF_AP-2 domain-containing protein. (470 aa)
	Tfap2a.L	TF_AP-2 domain-containing protein. (472 aa)
	grk7-2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
	Prkacb.S	Uncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	Rho.L	Rhodopsin. (459 aa)
	Arrb2.L	Arrestin_C domain-containing protein. (446 aa)
	LOC397896	G protein alpha subunit. (354 aa)
	rcvrn.2	MGC84117 protein. (192 aa)
	grk4	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (575 aa)
	A0A1L8EN80	Uncharacterized protein. (202 aa)
	A0A1L8EUU9	Uncharacterized protein. (202 aa)
	rcvrn.2-2	MGC84424 protein. (192 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EN80	Arr3.L	A0A1L8EN80	A0A1L8F6X4	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.466
A0A1L8EN80	Arrb2.L	A0A1L8EN80	A0A1L8H368	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.844
A0A1L8EN80	Rho.L	A0A1L8EN80	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.934
A0A1L8EN80	grk4	A0A1L8EN80	Q6DCW4	Uncharacterized protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.589
A0A1L8EN80	grk7-2	A0A1L8EN80	A0A1L8GB62	Uncharacterized protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.991
A0A1L8EUU9	Arr3.L	A0A1L8EUU9	A0A1L8F6X4	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.466
A0A1L8EUU9	Arrb2.L	A0A1L8EUU9	A0A1L8H368	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.844
A0A1L8EUU9	Rho.L	A0A1L8EUU9	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.933
A0A1L8EUU9	grk4	A0A1L8EUU9	Q6DCW4	Uncharacterized protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.589
A0A1L8EUU9	grk7-2	A0A1L8EUU9	A0A1L8GB62	Uncharacterized protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.991
Arr3.L	A0A1L8EN80	A0A1L8F6X4	A0A1L8EN80	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.466
Arr3.L	A0A1L8EUU9	A0A1L8F6X4	A0A1L8EUU9	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.466
Arr3.L	Rho.L	A0A1L8F6X4	A0A1L8GPJ9	Arrestin_C domain-containing protein.	Rhodopsin.	0.733
Arr3.L	grk7-2	A0A1L8F6X4	A0A1L8GB62	Arrestin_C domain-containing protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.404
Arr3.L	rcvrn.2	A0A1L8F6X4	Q68EX5	Arrestin_C domain-containing protein.	MGC84117 protein.	0.538
Arr3.L	rcvrn.2-2	A0A1L8F6X4	Q6DJE7	Arrestin_C domain-containing protein.	MGC84424 protein.	0.538
Arrb2.L	A0A1L8EN80	A0A1L8H368	A0A1L8EN80	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.844
Arrb2.L	A0A1L8EUU9	A0A1L8H368	A0A1L8EUU9	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.844
Arrb2.L	LOC397896	A0A1L8H368	B7ZR87	Arrestin_C domain-containing protein.	G protein alpha subunit.	0.500
Arrb2.L	Prkacb.S	A0A1L8H368	A0A1L8GLU4	Arrestin_C domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.547