73 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hras	Small G-protein H-Ras. (189 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Esr1.S	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
	ankrd6	ANK_REP_REGION domain-containing protein. (776 aa)
	cul3	CULLIN_2 domain-containing protein; Belongs to the cullin family. (768 aa)
	calm1	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	plek	Uncharacterized protein. (350 aa)
	ankrd6-2	ANK_REP_REGION domain-containing protein. (776 aa)
	cul3-2	CULLIN_2 domain-containing protein; Belongs to the cullin family. (768 aa)
	ryk	Uncharacterized protein. (596 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	prickle2	Uncharacterized protein. (833 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	nkd1	EF-hand domain-containing protein. (453 aa)
	cyld	Uncharacterized protein. (973 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	prickle2-2	Uncharacterized protein. (833 aa)
	sfrp1	Uncharacterized protein. (311 aa)
	calml4	Uncharacterized protein. (153 aa)
	net1	Uncharacterized protein. (584 aa)
	prickle1	Uncharacterized protein. (835 aa)
	wif1	Uncharacterized protein. (374 aa)
	Prickle1.L	Uncharacterized protein. (832 aa)
	net1-2	Uncharacterized protein. (583 aa)
	calml4-2	Uncharacterized protein. (152 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	Arrb2.L	Arrestin_C domain-containing protein. (446 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	klhl12	BTB domain-containing protein. (564 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	klhl12-2	BTB domain-containing protein. (564 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	map1b	Uncharacterized protein. (2247 aa)
	map1b-2	Uncharacterized protein. (2255 aa)
	A0A310U5I6	Arrestin_C domain-containing protein. (388 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	iqgap1	XIQGAP1 protein. (1657 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	ripk4a	Ripk4a protein. (720 aa)
	rac1	MGC114731 protein. (192 aa)
	krasl	Uncharacterized protein. (187 aa)
	rnf185	LOC495261 protein. (189 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	kras-2	Uncharacterized protein. (187 aa)
	rnf185-2	MGC84239 protein. (189 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	sfrp5	Secreted frizzled-related protein 5. (315 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)
	kras-3	LOC397771 protein. (186 aa)
	csnk1e	Casein kinase I epsilon; Belongs to the protein kinase superfamily. (416 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	Nek2	Nek2A. (442 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	Sirt7.L	Deacetylase sirtuin-type domain-containing protein. (393 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	daam1	Uncharacterized protein. (1077 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	prickle3-b	Prickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...] (536 aa)
	notch1	Uncharacterized protein. (2521 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (722 aa)
	Sfrp5.S	Uncharacterized protein. (315 aa)
	kras	Uncharacterized protein. (186 aa)
	Sirt2.S	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (402 aa)
	Arhgef19.L	Uncharacterized protein. (570 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	Sirt1.L	Deacetylase sirtuin-type domain-containing protein. (722 aa)
	dvl1	Uncharacterized protein. (606 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A310U5I6	Arrb2.L	A0A310U5I6	A0A1L8H368	Arrestin_C domain-containing protein.	Arrestin_C domain-containing protein.	0.901
A0A310U5I6	Axin1.S	A0A310U5I6	A0A1L8ER48	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.609
A0A310U5I6	calm1	A0A310U5I6	A0A1L8G5X8	Arrestin_C domain-containing protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.487
A0A310U5I6	calml4	A0A310U5I6	A0A1L8GSE0	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.412
A0A310U5I6	calml4-2	A0A310U5I6	A0A1L8H184	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.412
A0A310U5I6	dvl1	A0A310U5I6	A0A1L8FM70	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.582
A0A310U5I6	iqgap1	A0A310U5I6	B7ZRI7	Arrestin_C domain-containing protein.	XIQGAP1 protein.	0.441
A0A310U5I6	nkd1	A0A310U5I6	A0A1L8GKG8	Arrestin_C domain-containing protein.	EF-hand domain-containing protein.	0.479
Arhgef19.L	actl6a	A0A1L8FHI8	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.483
Arhgef19.L	daam1	A0A1L8FHI8	A0A1L8EZW6	Uncharacterized protein.	Uncharacterized protein.	0.873
Arhgef19.L	plek	A0A1L8FHI8	A0A1L8G6R7	Uncharacterized protein.	Uncharacterized protein.	0.426
Arhgef19.L	rac1	A0A1L8FHI8	Q58E25	Uncharacterized protein.	MGC114731 protein.	0.630
Arrb2.L	A0A310U5I6	A0A1L8H368	A0A310U5I6	Arrestin_C domain-containing protein.	Arrestin_C domain-containing protein.	0.901
Arrb2.L	Axin1.S	A0A1L8H368	A0A1L8ER48	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.609
Arrb2.L	actl6a	A0A1L8H368	Q7ZYI5	Arrestin_C domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.431
Arrb2.L	calm1	A0A1L8H368	A0A1L8G5X8	Arrestin_C domain-containing protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.611
Arrb2.L	calml4	A0A1L8H368	A0A1L8GSE0	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.548
Arrb2.L	calml4-2	A0A1L8H368	A0A1L8H184	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.548
Arrb2.L	ctnnb1	A0A1L8H368	Q63ZT4	Arrestin_C domain-containing protein.	Beta-catenin protein.	0.403
Arrb2.L	dvl1	A0A1L8H368	A0A1L8FM70	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.609