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| | ctnnb1 | Beta-catenin protein. (781 aa) |
| | krasl | Uncharacterized protein. (187 aa) |
| | tbp | LOC503680 protein. (296 aa) |
| | ccna2 | MGC130969 protein; Belongs to the cyclin family. (415 aa) |
| | parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa) |
| | dek | DEK_C domain-containing protein. (391 aa) |
| | Clspn.S | Claspin. (1286 aa) |
| | xsii-k1 | Transcription elongation factor XSII-K1. (645 aa) |
| | Stat5a | Signal transducer and activator of transcription. (781 aa) |
| | pten | Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa) |
| | Fanca.L | Fanconi_A_N domain-containing protein. (1423 aa) |
| | Rad17.L | Uncharacterized protein. (674 aa) |
| | cdc45 | Uncharacterized protein. (567 aa) |
| | Chek2.L | Uncharacterized protein. (392 aa) |
| | wrn | Uncharacterized protein. (1434 aa) |
| | Ccna2.S | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (415 aa) |
| | Ccna1.L | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (421 aa) |
| | ddx23-2 | Uncharacterized protein. (804 aa) |
| | rev1-2 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1237 aa) |
| | cdkn1a | Uncharacterized protein. (261 aa) |
| | nras | Uncharacterized protein. (189 aa) |
| | Cdk4.L | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa) |
| | Ccna1.S | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa) |
| | A0A1L8H9R2 | Uncharacterized protein. (1288 aa) |
| | Cdk2.S | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | ddx23 | Uncharacterized protein. (802 aa) |
| | rev1 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1230 aa) |
| | gabpa | Uncharacterized protein. (454 aa) |
| | myc | Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa) |
| | chd4 | B230399n07 protein. (1893 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa) |
| | ccnd1 | Ccnd1-prov protein; Belongs to the cyclin family. (291 aa) |
| | rrm2b | MGC52676 protein. (386 aa) |
| | Hus1 | Checkpoint protein; Belongs to the HUS1 family. (282 aa) |
| | hras | Small G-protein H-Ras. (189 aa) |
| | kras-3 | LOC397771 protein. (186 aa) |
| | tcea1 | TFIIS elongation factor. (303 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | Tipin.S | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (361 aa) |
| | Rad52.S | Uncharacterized protein. (429 aa) |
| | Wee2 | Wee1-like protein kinase. (534 aa) |
| | Mcm2.L | DNA helicase; Belongs to the MCM family. (886 aa) |
| | fancd2 | Uncharacterized protein. (1445 aa) |
| | mst1 | Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (718 aa) |
| | Rad26 | Uncharacterized protein. (798 aa) |
| | Rnf2.L | RING-type domain-containing protein. (354 aa) |
| | Orc1.L | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (886 aa) |
| | ccne1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa) |
| | Cyba.L | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (187 aa) |
| | cdh3 | Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa) |
| | cdh1 | Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa) |
| | mus81 | ERCC4 domain-containing protein. (613 aa) |
| | lmo2-2 | Uncharacterized protein. (158 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (885 aa) |
| | Mst1.S | Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (716 aa) |
| | atrip | Uncharacterized protein. (801 aa) |
| | top1.2 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (770 aa) |
| | Ccne1.S | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa) |
| | Cdh1.S | Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (914 aa) |
| | Wee1.S | Wee1-like protein kinase. (595 aa) |
| | lmo2 | Uncharacterized protein. (158 aa) |
| | ddb1 | CPSF_A domain-containing protein. (1140 aa) |
| | rrm2.1 | Uncharacterized protein. (378 aa) |
| | Rrm2.2.L | Uncharacterized protein. (386 aa) |
| | hltf | Uncharacterized protein. (1000 aa) |
| | Atr.L | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa) |
| | xrn2 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (931 aa) |
| | Dut.L | dUTPase domain-containing protein. (208 aa) |
| | E2f7.L | Uncharacterized protein. (891 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (858 aa) |
| | Bcl2.S | BH4_2 domain-containing protein. (253 aa) |
| | paxip1 | Uncharacterized protein. (1334 aa) |
| | Cdc25a.S | Rhodanese domain-containing protein. (172 aa) |
| | Tcea3.S | Uncharacterized protein. (398 aa) |
| | Cdc6.L | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (645 aa) |
| | Dbf4b.L | DBF4-type domain-containing protein. (784 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1275 aa) |
| | Brca1.L | Uncharacterized protein. (1582 aa) |
| | top1.1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (821 aa) |
| | Eme1.L | ERCC4 domain-containing protein. (411 aa) |
| | recql5 | Uncharacterized protein. (1090 aa) |
| | smarcal1 | Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (960 aa) |
| | zranb3 | Uncharacterized protein. (1110 aa) |
| | abcc6 | Uncharacterized protein. (1498 aa) |
| | slx4 | BTB domain-containing protein. (1773 aa) |
| | Dicer1.S | Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1768 aa) |
| | Exo1.S | Uncharacterized protein. (734 aa) |
| | Ring1.S | RING-type domain-containing protein. (376 aa) |
| | lamtor2 | Robl_LC7 domain-containing protein. (125 aa) |
| | dicer1 | Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1891 aa) |
| | Fancm.L | Uncharacterized protein. (2165 aa) |
| | aqr | Uncharacterized protein. (1566 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa) |
| | lamtor2-2 | Robl_LC7 domain-containing protein. (125 aa) |
| | Aicda.S | CMP/dCMP-type deaminase domain-containing protein. (275 aa) |
| | Dna2.S | Uncharacterized protein. (1053 aa) |
| | chek1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa) |
| | kras | Uncharacterized protein. (186 aa) |
| | Aicda.L | CMP/dCMP-type deaminase domain-containing protein. (196 aa) |
| | ercc1 | Uncharacterized protein. (297 aa) |
| | chek1-2 | Protein kinase domain-containing protein. (510 aa) |
| | topbp1 | Uncharacterized protein. (1573 aa) |
| | Wrnip1.L | Uncharacterized protein. (572 aa) |
| | Mcm4.S | DNA helicase; Belongs to the MCM family. (863 aa) |
| | Prkdc.L | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4146 aa) |
| | Maf1.L | Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (256 aa) |
| | Paxip1.L | Uncharacterized protein. (1320 aa) |
| | Myc.S | Myc_N domain-containing protein. (176 aa) |
| | dbf4 | Uncharacterized protein. (661 aa) |
| | top2a | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1579 aa) |
| | gabpa-2 | Gabpa-prov protein. (452 aa) |
| | kras-2 | Uncharacterized protein. (187 aa) |
| | Tp53.L | P53 domain-containing protein. (137 aa) |
| | Mrc1.L | C-type lectin domain-containing protein. (220 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (362 aa) |
| | mdm2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa) |
| | Cdc25c1 | Rhodanese domain-containing protein. (550 aa) |
| | e2f7 | Uncharacterized protein. (859 aa) |
| | ticrr | Treslin_N domain-containing protein. (1968 aa) |
