STRINGSTRING
Frzb-1 Frzb-1 fzd2 fzd2 Nfatc2.S Nfatc2.S sumo2 sumo2 A0A1L8ENI4 A0A1L8ENI4 cxcr4 cxcr4 Frzb.S Frzb.S fzd5 fzd5 crebbp crebbp Axin1.S Axin1.S stat3.1 stat3.1 nfatc2 nfatc2 A0A1L8EUY4 A0A1L8EUY4 wnt6 wnt6 Cxcr4.L Cxcr4.L fzd7 fzd7 crebbp-2 crebbp-2 Notch1.S Notch1.S tgfb1 tgfb1 notch1 notch1 wnt11b wnt11b tgfb1-2 tgfb1-2 Sfrp5.S Sfrp5.S wnt4 wnt4 dkk1 dkk1 wnt4-2 wnt4-2 axin2 axin2 Fzd6.S Fzd6.S wnt3a wnt3a Fzd8.L Fzd8.L fzd1 fzd1 sfrp4 sfrp4 fzd6 fzd6 Esr1.S Esr1.S prdm1 prdm1 pik3cb pik3cb A0A1L8G525 A0A1L8G525 fzd3 fzd3 rspo3 rspo3 prdm1-2 prdm1-2 pik3cb-2 pik3cb-2 ryk ryk sdc1 sdc1 Lgr4.S Lgr4.S Dkk3.S Dkk3.S ep300 ep300 lgr4 lgr4 Lrp5.L Lrp5.L nfatc3 nfatc3 Jun.L Jun.L ep300-2 ep300-2 Rho.L Rho.L Wnt5b.S Wnt5b.S sfrp1 sfrp1 pik3cg pik3cg wnt16 wnt16 lgr5 lgr5 wif1 wif1 Lgr5.L Lgr5.L wnt16-2 wnt16-2 Sfrp1.L Sfrp1.L bcl9 bcl9 rnf43 rnf43 tnfsf11 tnfsf11 wnt1 wnt1 Bcl9.L Bcl9.L Tnfsf11.L Tnfsf11.L Wnt1.L Wnt1.L wnt10b wnt10b wnt11 wnt11 casp3.2 casp3.2 lef1 lef1 ror2 ror2 Znrf3.S Znrf3.S Casp3.L Casp3.L sfrp2 sfrp2 znrf3 znrf3 wnt6-2 wnt6-2 wif1-2 wif1-2 nf-at nf-at fz3 fz3 xfz8 xfz8 wnt7b wnt7b dkk1-2 dkk1-2 src src rac1 rac1 ctnnb1 ctnnb1 axin2-2 axin2-2 dcn dcn dcn-2 dcn-2 myc myc esr1 esr1 rhoa rhoa sfrp2-2 sfrp2-2 ror2-2 ror2-2 ccnd1 ccnd1 sfrp5 sfrp5 lef1-2 lef1-2 c-Jun c-Jun tnfsf13b tnfsf13b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Frzb-1Uncharacterized protein. (319 aa)
fzd2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
Nfatc2.SRHD domain-containing protein. (884 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
A0A1L8ENI4Uncharacterized protein. (815 aa)
cxcr4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Frzb.SUncharacterized protein. (319 aa)
fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
crebbpUncharacterized protein. (2424 aa)
Axin1.SUncharacterized protein. (839 aa)
stat3.1Signal transducer and activator of transcription. (769 aa)
nfatc2RHD domain-containing protein. (896 aa)
A0A1L8EUY4Uncharacterized protein. (818 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Cxcr4.LG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
fzd7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
crebbp-2Uncharacterized protein. (2453 aa)
Notch1.SUncharacterized protein. (2524 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
notch1Uncharacterized protein. (2521 aa)
wnt11bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
Sfrp5.SUncharacterized protein. (315 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
dkk1Dickkopf_N domain-containing protein. (263 aa)
wnt4-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
axin2Uncharacterized protein. (707 aa)
Fzd6.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Fzd8.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
fzd1Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
sfrp4Uncharacterized protein. (353 aa)
fzd6Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
Esr1.SEstrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
prdm1Uncharacterized protein. (780 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
A0A1L8G525Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (704 aa)
fzd3Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
rspo3Uncharacterized protein. (253 aa)
prdm1-2Uncharacterized protein. (780 aa)
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
rykUncharacterized protein. (596 aa)
sdc1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (607 aa)
Lgr4.SG_PROTEIN_RECEP_F1_2 domain-containing protein. (956 aa)
Dkk3.SDickkopf_N domain-containing protein. (257 aa)
ep300Uncharacterized protein. (2495 aa)
lgr4G_PROTEIN_RECEP_F1_2 domain-containing protein. (953 aa)
Lrp5.LUncharacterized protein. (1517 aa)
nfatc3RHD domain-containing protein. (885 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
ep300-2Uncharacterized protein. (2492 aa)
Rho.LRhodopsin. (459 aa)
Wnt5b.SProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
sfrp1Uncharacterized protein. (311 aa)
pik3cgUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
lgr5G_PROTEIN_RECEP_F1_2 domain-containing protein. (902 aa)
wif1Uncharacterized protein. (374 aa)
Lgr5.LG_PROTEIN_RECEP_F1_2 domain-containing protein. (902 aa)
wnt16-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
Sfrp1.LUncharacterized protein. (311 aa)
bcl9BCL9 domain-containing protein. (1473 aa)
rnf43RING-type domain-containing protein. (664 aa)
tnfsf11TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (290 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
Bcl9.LBCL9 domain-containing protein. (1387 aa)
Tnfsf11.LTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (290 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
casp3.2Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
lef1HMG box domain-containing protein. (372 aa)
ror2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
Znrf3.SRING-type domain-containing protein. (848 aa)
Casp3.LUncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
sfrp2Uncharacterized protein. (295 aa)
znrf3RING-type domain-containing protein. (854 aa)
wnt6-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
wif1-2Wnt inhibitory factor-1. (374 aa)
nf-atNuclear factor of activated T-cell. (884 aa)
fz3Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
xfz8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
srcTyrosine-protein kinase. (532 aa)
rac1MGC114731 protein. (192 aa)
ctnnb1Beta-catenin protein. (781 aa)
axin2-2MGC81576 protein. (707 aa)
dcnDecorin; May affect the rate of fibrils formation. (364 aa)
dcn-2Decorin; May affect the rate of fibrils formation. (364 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
rhoaMGC64296 protein. (193 aa)
sfrp2-2Sfrp2-prov protein. (298 aa)
ror2-2Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
ccnd1Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
sfrp5Secreted frizzled-related protein 5. (315 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
tnfsf13bBAFF; Belongs to the tumor necrosis factor family. (266 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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