(67 nodes) (2018) The role of microtubules in the regulation of epithelial junctions. network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pard6b	Uncharacterized protein. (377 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	clip1	Uncharacterized protein. (2362 aa)
	Tjp2.L	Uncharacterized protein. (430 aa)
	f11r	LOC398627 protein. (291 aa)
	X-Delta-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
	rac1	MGC114731 protein. (192 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	rac3	RAC1 protein. (192 aa)
	prkaca	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (560 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	tjp3-2	MGC52795 protein; Belongs to the MAGUK family. (1010 aa)
	rhoa	MGC64296 protein. (193 aa)
	jup	LOC398496 protein. (737 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (560 aa)
	Aurka.S	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (408 aa)
	Ndel1.S	NUDE_C domain-containing protein. (368 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	ndel1	NUDE_C domain-containing protein. (350 aa)
	Camsap1.S	Uncharacterized protein. (1576 aa)
	cgn	Myosin_tail_1 domain-containing protein. (1368 aa)
	F11r.S	Uncharacterized protein. (289 aa)
	cldn2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
	nin	Uncharacterized protein. (2076 aa)
	cgn-2	Myosin_tail_1 domain-containing protein. (1368 aa)
	cdk1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
	Arhgef19.L	Uncharacterized protein. (570 aa)
	Cdk1.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	dsg2	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1146 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	Trio.L	Uncharacterized protein. (1879 aa)
	Dsp.L	Uncharacterized protein. (2802 aa)
	dsg2-2	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1152 aa)
	dsc3	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (898 aa)
	Ect2.S	Uncharacterized protein. (987 aa)
	Mapre3.S	Uncharacterized protein. (316 aa)
	ect2	Uncharacterized protein. (986 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	Arhgap1.S	Uncharacterized protein. (473 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	cdh5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
	kifc3	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (850 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
	kifap3	Uncharacterized protein. (793 aa)
	plekha7	Uncharacterized protein. (1265 aa)
	Arhgap1.L	Uncharacterized protein. (435 aa)
	cdh5-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	kifc3-2	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (856 aa)
	Prkacb.S	Uncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
	patj	Uncharacterized protein. (1796 aa)
	Kifap3.L	Uncharacterized protein. (794 aa)
	Rho.L	Rhodopsin. (459 aa)
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	kif23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (962 aa)
	camsap3	Uncharacterized protein. (1315 aa)
	pkn1	Uncharacterized protein. (942 aa)
	Racgap1.S	Uncharacterized protein. (629 aa)
	Racgap1.L	Uncharacterized protein. (629 aa)
	Spef1.S	Calponin-homology (CH) domain-containing protein. (136 aa)
	stk11	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	Clip1.S	Uncharacterized protein. (2319 aa)
	tjp3	Uncharacterized protein; Belongs to the MAGUK family. (1025 aa)
	stk11-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arhgap1.L	Arhgef19.L	A0A1L8GIS6	A0A1L8FHI8	Uncharacterized protein.	Uncharacterized protein.	0.551
Arhgap1.L	Ect2.S	A0A1L8GIS6	A0A1L8G450	Uncharacterized protein.	Uncharacterized protein.	0.844
Arhgap1.L	Ndel1.S	A0A1L8GIS6	A0A1L8EN91	Uncharacterized protein.	NUDE_C domain-containing protein.	0.514
Arhgap1.L	Racgap1.L	A0A1L8GIS6	A0A1L8HIP3	Uncharacterized protein.	Uncharacterized protein.	0.439
Arhgap1.L	Racgap1.S	A0A1L8GIS6	A0A1L8HA98	Uncharacterized protein.	Uncharacterized protein.	0.461
Arhgap1.L	Rho.L	A0A1L8GIS6	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.477
Arhgap1.L	Tjp1.S	A0A1L8GIS6	A0A1L8H090	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.486
Arhgap1.L	Tjp2.L	A0A1L8GIS6	A0A1L8HYU8	Uncharacterized protein.	Uncharacterized protein.	0.457
Arhgap1.L	actl6a	A0A1L8GIS6	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.793
Arhgap1.L	cdh11-2	A0A1L8GIS6	O93264	Uncharacterized protein.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.602
Arhgap1.L	ctnnb1	A0A1L8GIS6	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.590
Arhgap1.L	ect2	A0A1L8GIS6	A0A1L8GAI2	Uncharacterized protein.	Uncharacterized protein.	0.844
Arhgap1.L	jup	A0A1L8GIS6	Q6NU15	Uncharacterized protein.	LOC398496 protein.	0.517
Arhgap1.L	kif23	A0A1L8GIS6	A0A1L8H194	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.420
Arhgap1.L	ndel1	A0A1L8GIS6	A0A1L8EUX1	Uncharacterized protein.	NUDE_C domain-containing protein.	0.514
Arhgap1.L	rac1	A0A1L8GIS6	Q58E25	Uncharacterized protein.	MGC114731 protein.	0.813
Arhgap1.L	rac3	A0A1L8GIS6	Q9PW31	Uncharacterized protein.	RAC1 protein.	0.760
Arhgap1.L	rhoa	A0A1L8GIS6	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.900
Arhgap1.L	tjp3	A0A1L8GIS6	A0A1L8HW84	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.507
Arhgap1.L	tjp3-2	A0A1L8GIS6	Q7ZTN1	Uncharacterized protein.	MGC52795 protein; Belongs to the MAGUK family.	0.507