41 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	six2-2	Homeobox domain-containing protein. (289 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	Nfatc2.S	RHD domain-containing protein. (884 aa)
	krt8.2	IF rod domain-containing protein; Belongs to the intermediate filament family. (451 aa)
	Fn1.S	Uncharacterized protein. (2480 aa)
	wnt9b.2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	nfatc2	RHD domain-containing protein. (896 aa)
	krt8.2-2	IF rod domain-containing protein; Belongs to the intermediate filament family. (451 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	actb	Uncharacterized protein. (375 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	itga8	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1088 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	itga8-2	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1060 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	etv4	ETS domain-containing protein. (477 aa)
	six2	Homeobox domain-containing protein. (289 aa)
	mmut	B12-binding domain-containing protein. (758 aa)
	Ptk7.L	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
	ryk	Uncharacterized protein. (596 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	nfatc3	RHD domain-containing protein. (885 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (497 aa)
	Junb.L	BZIP domain-containing protein. (306 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	krt8.1	IF rod domain-containing protein; Belongs to the intermediate filament family. (512 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	foxd1	Fork-head domain-containing protein. (333 aa)
	Gdnf.L	TGF_BETA_2 domain-containing protein. (332 aa)
	fos	BZIP domain-containing protein. (369 aa)
	nf-at	Nuclear factor of activated T-cell. (884 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	golga2	MGC81213 protein. (968 aa)
	fos-2	MGC80305 protein. (368 aa)
	krt8.1-2	Krt8 protein; Belongs to the intermediate filament family. (507 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdh3.S	Fn1.S	A0A1L8GET9	A0A1L8EPN8	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.869
Cdh3.S	Jun.L	A0A1L8GET9	A0A1L8GLZ4	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	BZIP domain-containing protein; Belongs to the bZIP family.	0.593
Cdh3.S	c-Jun	A0A1L8GET9	Q9PVZ1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	C-Jun protein; Belongs to the bZIP family.	0.593
Cdh3.S	cdh3	A0A1L8GET9	A0A1L8GKW6	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
Cdh3.S	ctnnb1	A0A1L8GET9	Q63ZT4	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Beta-catenin protein.	0.999
Cdh3.S	fzd7	A0A1L8GET9	A0A1L8EX17	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.432
Cdh3.S	krt8.1	A0A1L8GET9	A0A1L8HIP9	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.494
Cdh3.S	krt8.1-2	A0A1L8GET9	Q7ZXU4	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Krt8 protein; Belongs to the intermediate filament family.	0.502
Cdh3.S	six2	A0A1L8GET9	A0A1L8G1C7	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Homeobox domain-containing protein.	0.428
Cdh3.S	six2-2	A0A1L8GET9	A0A1L8G6B6	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Homeobox domain-containing protein.	0.428
Cdh3.S	wnt11	A0A1L8GET9	A0A1L8HJX1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.551
Cdh3.S	wnt11b	A0A1L8GET9	A0A1L8F6W4	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.557
Fn1.S	Cdh3.S	A0A1L8EPN8	A0A1L8GET9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.869
Fn1.S	cdh3	A0A1L8EPN8	A0A1L8GKW6	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.919
Fn1.S	ctnnb1	A0A1L8EPN8	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.720
Fn1.S	fzd7	A0A1L8EPN8	A0A1L8EX17	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.481
Fn1.S	itga8	A0A1L8EPN8	A0A1L8FQW6	Uncharacterized protein.	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	0.937
Fn1.S	itga8-2	A0A1L8EPN8	A0A1L8FVP9	Uncharacterized protein.	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	0.937
Fzd4.S	Ptk7.L	A0A1L8HB90	A0A1L8G6L8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.482
Fzd4.S	ctnnb1	A0A1L8HB90	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.871