(26 nodes) (2019) Evolution and Functional Differentiation of the Diaphragm Muscle of Mammals. network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	myf6	Myogenic factor. (241 aa)
	bdnf-2	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	Myod1.L	Myogenic factor. (289 aa)
	myog	Myogenin U1. (235 aa)
	A0A1L8EPG7	Uncharacterized protein. (18453 aa)
	A0A1L8EWK4	Uncharacterized protein. (9925 aa)
	MyHC	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
	A0A1L8FG40	Uncharacterized protein. (2091 aa)
	A0A1L8FLY9	Uncharacterized protein. (1971 aa)
	egfr	Receptor protein-tyrosine kinase. (1208 aa)
	id4	BHLH domain-containing protein. (131 aa)
	egfr-2	Receptor protein-tyrosine kinase. (1210 aa)
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	cdh15	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (792 aa)
	mef2a	MADS-box domain-containing protein. (501 aa)
	Tm7	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	Met.S	Uncharacterized protein. (1354 aa)
	myf5	Myogenic factor. (255 aa)
	Met.L	Uncharacterized protein. (1355 aa)
	Mef2a.L	MADS-box domain-containing protein. (516 aa)
	Myog.S	BHLH domain-containing protein. (236 aa)
	Musk.S	Uncharacterized protein. (942 aa)
	MRF4	MRF4a. (240 aa)
	XMyf-5	Myogenic factor. (255 aa)
	myod1-a	Myoblast determination protein 1 homolog A; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (289 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EPG7	MRF4	A0A1L8EPG7	B7ZQB0	Uncharacterized protein.	MRF4a.	0.487
A0A1L8EPG7	MyHC	A0A1L8EPG7	A0A1L8F427	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.655
A0A1L8EPG7	Myod1.L	A0A1L8EPG7	A0A1L8GI72	Uncharacterized protein.	Myogenic factor.	0.448
A0A1L8EPG7	Myog.S	A0A1L8EPG7	A0A1L8H6H3	Uncharacterized protein.	BHLH domain-containing protein.	0.431
A0A1L8EPG7	Tm7	A0A1L8EPG7	A0A1L8GTE7	Uncharacterized protein.	Uncharacterized protein; Belongs to the tropomyosin family.	0.612
A0A1L8EPG7	actl6a	A0A1L8EPG7	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.873
A0A1L8EPG7	myf6	A0A1L8EPG7	Q5U4S0	Uncharacterized protein.	Myogenic factor.	0.486
A0A1L8EPG7	myod1-a	A0A1L8EPG7	P13904	Uncharacterized protein.	Myoblast determination protein 1 homolog A; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.	0.448
A0A1L8EPG7	myog	A0A1L8EPG7	Q8UUX8	Uncharacterized protein.	Myogenin U1.	0.431
A0A1L8EWK4	MRF4	A0A1L8EWK4	B7ZQB0	Uncharacterized protein.	MRF4a.	0.487
A0A1L8EWK4	MyHC	A0A1L8EWK4	A0A1L8F427	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.655
A0A1L8EWK4	Myod1.L	A0A1L8EWK4	A0A1L8GI72	Uncharacterized protein.	Myogenic factor.	0.448
A0A1L8EWK4	Myog.S	A0A1L8EWK4	A0A1L8H6H3	Uncharacterized protein.	BHLH domain-containing protein.	0.431
A0A1L8EWK4	Tm7	A0A1L8EWK4	A0A1L8GTE7	Uncharacterized protein.	Uncharacterized protein; Belongs to the tropomyosin family.	0.612
A0A1L8EWK4	actl6a	A0A1L8EWK4	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.873
A0A1L8EWK4	myf6	A0A1L8EWK4	Q5U4S0	Uncharacterized protein.	Myogenic factor.	0.486
A0A1L8EWK4	myod1-a	A0A1L8EWK4	P13904	Uncharacterized protein.	Myoblast determination protein 1 homolog A; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.	0.448
A0A1L8EWK4	myog	A0A1L8EWK4	Q8UUX8	Uncharacterized protein.	Myogenin U1.	0.431
A0A1L8FG40	A0A1L8FLY9	A0A1L8FG40	A0A1L8FLY9	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8FG40	Musk.S	A0A1L8FG40	A0A1L8HNT6	Uncharacterized protein.	Uncharacterized protein.	0.989