STRINGSTRING
Xporc-d Xporc-d esr1 esr1 sfrp2-2 sfrp2-2 Dkk3.S Dkk3.S hdac1-2 hdac1-2 creb1 creb1 sfrp5 sfrp5 prkaca prkaca lef1-2 lef1-2 dkk2-2 dkk2-2 c-Jun c-Jun actl6a actl6a wls wls prkacb prkacb lgr4 lgr4 Lrp5.L Lrp5.L Prkacb.S Prkacb.S Wls.L Wls.L Jun.L Jun.L Prkcd.S Prkcd.S wnt16 wnt16 Hdac3.S Hdac3.S wif1 wif1 wnt16-2 wnt16-2 A0A1L8H5Q6 A0A1L8H5Q6 fzd9 fzd9 rnf43 rnf43 tnfsf11 tnfsf11 wnt1 wnt1 hdac7 hdac7 Sp7.S Sp7.S Mmp13.S Mmp13.S Mmp13l.S Mmp13l.S fzd9-2 fzd9-2 hdac1 hdac1 Tnfsf11.L Tnfsf11.L Wnt1.L Wnt1.L wnt10b wnt10b hdac7-2 hdac7-2 Mmp3.L Mmp3.L mmp13l mmp13l wnt11 wnt11 lef1 lef1 dkk2 dkk2 A0A1L8HPW4 A0A1L8HPW4 fzd10 fzd10 Znrf3.S Znrf3.S mef2c mef2c sfrp2 sfrp2 lif lif znrf3 znrf3 mef2c-2 mef2c-2 ctsk ctsk fos fos wnt6-2 wnt6-2 wif1-2 wif1-2 rspo2 rspo2 nf-at nf-at wnt10a-2 wnt10a-2 xfz8 xfz8 wnt7b wnt7b dkk1-2 dkk1-2 src src ewsr1 ewsr1 ctnnb1 ctnnb1 fos-2 fos-2 Hdac5.S Hdac5.S wnt10a wnt10a hdac4 hdac4 Axin1.S Axin1.S hdac5 hdac5 wnt6 wnt6 Hdac4.L Hdac4.L Itgav.L Itgav.L tgfb1 tgfb1 A0A1L8F4F9 A0A1L8F4F9 wnt11b wnt11b tgfb1-2 tgfb1-2 A0A1L8FBU8 A0A1L8FBU8 A0A1L8FBV9 A0A1L8FBV9 Sfrp5.S Sfrp5.S A0A1L8FG40 A0A1L8FG40 wnt4 wnt4 dkk1 dkk1 A0A1L8FLY9 A0A1L8FLY9 wnt4-2 wnt4-2 nfatc1 nfatc1 wnt3a wnt3a Fzd8.L Fzd8.L fzd1 fzd1 sfrp4 sfrp4 nfatc1-2 nfatc1-2 Esr1.S Esr1.S A0A1L8G2V6 A0A1L8G2V6 A0A1L8G5J6 A0A1L8G5J6 rspo3 rspo3 A0A1L8G8Y0 A0A1L8G8Y0 Runx2.L Runx2.L Lgr4.S Lgr4.S
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Xporc-dXporc-d protein; Belongs to the membrane-bound acyltransferase family. (450 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
sfrp2-2Sfrp2-prov protein. (298 aa)
Dkk3.SDickkopf_N domain-containing protein. (257 aa)
hdac1-2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa)
creb1Creb1-prov protein. (324 aa)
sfrp5Secreted frizzled-related protein 5. (315 aa)
prkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
dkk2-2Dickkopf homolog 2. (255 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
wlsUncharacterized protein. (541 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
lgr4G_PROTEIN_RECEP_F1_2 domain-containing protein. (953 aa)
Lrp5.LUncharacterized protein. (1517 aa)
Prkacb.SUncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
Wls.LUncharacterized protein. (541 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
Prkcd.SProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (806 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
Hdac3.SHistone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (405 aa)
wif1Uncharacterized protein. (374 aa)
wnt16-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
A0A1L8H5Q6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
fzd9Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
rnf43RING-type domain-containing protein. (664 aa)
tnfsf11TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (290 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
hdac7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (972 aa)
Sp7.SUncharacterized protein. (409 aa)
Mmp13.SZnMc domain-containing protein. (258 aa)
Mmp13l.SZnMc domain-containing protein. (472 aa)
fzd9-2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa)
Tnfsf11.LTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (290 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
hdac7-2Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (957 aa)
Mmp3.LZnMc domain-containing protein. (503 aa)
mmp13lZnMc domain-containing protein. (472 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
lef1HMG box domain-containing protein. (372 aa)
dkk2Dickkopf_N domain-containing protein. (255 aa)
A0A1L8HPW4Uncharacterized protein. (216 aa)
fzd10Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
Znrf3.SRING-type domain-containing protein. (848 aa)
mef2cMADS-box domain-containing protein. (464 aa)
sfrp2Uncharacterized protein. (295 aa)
lifUncharacterized protein. (216 aa)
znrf3RING-type domain-containing protein. (854 aa)
mef2c-2MADS-box domain-containing protein. (464 aa)
ctskLOC100127265 protein; Belongs to the peptidase C1 family. (331 aa)
fosBZIP domain-containing protein. (369 aa)
wnt6-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
wif1-2Wnt inhibitory factor-1. (374 aa)
rspo2R-spondin 2. (243 aa)
nf-atNuclear factor of activated T-cell. (884 aa)
wnt10a-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
xfz8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
srcTyrosine-protein kinase. (532 aa)
ewsr1Uncharacterized protein. (671 aa)
ctnnb1Beta-catenin protein. (781 aa)
fos-2MGC80305 protein. (368 aa)
Hdac5.SHistone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1048 aa)
wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
Axin1.SUncharacterized protein. (839 aa)
hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1016 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Hdac4.LHistone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1171 aa)
Itgav.LIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1080 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
A0A1L8F4F9Uncharacterized protein; Belongs to the peptidase C1 family. (329 aa)
wnt11bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
A0A1L8FBU8Uncharacterized protein; Belongs to the peptidase C1 family. (331 aa)
A0A1L8FBV9Uncharacterized protein; Belongs to the peptidase C1 family. (331 aa)
Sfrp5.SUncharacterized protein. (315 aa)
A0A1L8FG40Uncharacterized protein. (2091 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
dkk1Dickkopf_N domain-containing protein. (263 aa)
A0A1L8FLY9Uncharacterized protein. (1971 aa)
wnt4-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
nfatc1RHD domain-containing protein. (955 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Fzd8.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
fzd1Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
sfrp4Uncharacterized protein. (353 aa)
nfatc1-2RHD domain-containing protein. (933 aa)
Esr1.SEstrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
A0A1L8G2V6Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (467 aa)
A0A1L8G5J6Runt-related transcription factor. (451 aa)
rspo3Uncharacterized protein. (253 aa)
A0A1L8G8Y0Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
Runx2.LRunt-related transcription factor. (455 aa)
Lgr4.SG_PROTEIN_RECEP_F1_2 domain-containing protein. (956 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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