43 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	e2f1	E2F_TDP domain-containing protein. (427 aa)
	kpna7	Importin subunit alpha; Belongs to the importin alpha family. (522 aa)
	aurka	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (407 aa)
	atf2	Uncharacterized protein. (486 aa)
	relb	RHD domain-containing protein. (500 aa)
	map4	Microtubule-associated protein. (1211 aa)
	Tgfbr1.S	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (454 aa)
	Sdcbp	Uncharacterized protein. (295 aa)
	Map4.L	Microtubule-associated protein. (1234 aa)
	e2f3	E2F_TDP domain-containing protein. (425 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	e2f6	E2F_TDP domain-containing protein. (260 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	xpo1	Importin N-terminal domain-containing protein. (1071 aa)
	Rel.L	RHD domain-containing protein. (583 aa)
	E2f6.L	E2F_TDP domain-containing protein. (257 aa)
	Ctrl.L	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
	hmox1	Uncharacterized protein. (287 aa)
	Rpl32.L	Uncharacterized protein. (167 aa)
	Fkbp4.S	Peptidylprolyl isomerase. (447 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	hgf-2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	gtsf1	Uncharacterized protein. (225 aa)
	clip1	Uncharacterized protein. (2362 aa)
	kif2a	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (705 aa)
	e2f1-2	LOC100036852 protein. (426 aa)
	relb-A	V-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog. (497 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	sdcbp	MGC81274 protein. (295 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	kpna3	Importin subunit alpha; Belongs to the importin alpha family. (521 aa)
	fkbp4	Peptidylprolyl isomerase. (447 aa)
	xpo1-2	Xpo1 protein. (1071 aa)
	kpna4	Importin subunit alpha; Belongs to the importin alpha family. (520 aa)
	MGC52622	MGC52622 protein. (290 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	e2f3-2	Transcription factor E2F. (429 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fkbp4.S	relb	A0A1L8GQX7	A0A1L8F873	Peptidylprolyl isomerase.	RHD domain-containing protein.	0.509
Fkbp4.S	relb-A	A0A1L8GQX7	B7ZS26	Peptidylprolyl isomerase.	V-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog.	0.509
Jun.L	Rel.L	A0A1L8GLZ4	A0A1L8G7B6	BZIP domain-containing protein; Belongs to the bZIP family.	RHD domain-containing protein.	0.555
Jun.L	atf2	A0A1L8GLZ4	A0A1L8EWJ3	BZIP domain-containing protein; Belongs to the bZIP family.	Uncharacterized protein.	0.917
Jun.L	bmp4-2	A0A1L8GLZ4	Q91703	BZIP domain-containing protein; Belongs to the bZIP family.	Bone morphogenetic protein 4.	0.505
Jun.L	c-Jun	A0A1L8GLZ4	Q9PVZ1	BZIP domain-containing protein; Belongs to the bZIP family.	C-Jun protein; Belongs to the bZIP family.	0.958
Jun.L	ctnnb1	A0A1L8GLZ4	Q63ZT4	BZIP domain-containing protein; Belongs to the bZIP family.	Beta-catenin protein.	0.936
Jun.L	e2f1	A0A1L8GLZ4	A0A1L8EMM8	BZIP domain-containing protein; Belongs to the bZIP family.	E2F_TDP domain-containing protein.	0.493
Jun.L	e2f1-2	A0A1L8GLZ4	A1L2H8	BZIP domain-containing protein; Belongs to the bZIP family.	LOC100036852 protein.	0.493
Jun.L	e2f3-2	A0A1L8GLZ4	Q9IB10	BZIP domain-containing protein; Belongs to the bZIP family.	Transcription factor E2F.	0.401
Jun.L	hmox1	A0A1L8GLZ4	A0A1L8GNF4	BZIP domain-containing protein; Belongs to the bZIP family.	Uncharacterized protein.	0.419
MGC52622	gtsf1	Q801P2	A0A1L8HID9	MGC52622 protein.	Uncharacterized protein.	0.428
Map4.L	Stmn1.S	A0A1L8FUT9	A0A1L8H795	Microtubule-associated protein.	Uncharacterized protein.	0.745
Map4.L	clip1	A0A1L8FUT9	A0A1L8I128	Microtubule-associated protein.	Uncharacterized protein.	0.723
Map4.L	stmn1	A0A1L8FUT9	A0A1L8HEF1	Microtubule-associated protein.	Stathmin; Belongs to the stathmin family.	0.759
Map4.L	stmn2	A0A1L8FUT9	A0A1L8FZA7	Microtubule-associated protein.	Stathmin; Belongs to the stathmin family.	0.630
Map4.L	stmn2-2	A0A1L8FUT9	Q6DJD4	Microtubule-associated protein.	Stathmin; Belongs to the stathmin family.	0.667
Map4.L	stmn3	A0A1L8FUT9	Q4KLA7	Microtubule-associated protein.	Stathmin; Belongs to the stathmin family.	0.676
Map4.L	stmn3-2	A0A1L8FUT9	Q8AVQ7	Microtubule-associated protein.	Stathmin; Belongs to the stathmin family.	0.676
Map4.L	stmn4	A0A1L8FUT9	A0A1L8G5Z4	Microtubule-associated protein.	Stathmin; Belongs to the stathmin family.	0.599