STRINGSTRING
rad50-2 rad50-2 rad50 rad50 A0A1L8GS29 A0A1L8GS29 Traip.L Traip.L top1.2 top1.2 Znf451.L Znf451.L Rbbp8.L Rbbp8.L rbbp8 rbbp8 Tdp2.S Tdp2.S Tdp1.L Tdp1.L Sumo1.L Sumo1.L top1.1 top1.1 Brca1.L Brca1.L Sumo1.S Sumo1.S sumo2 sumo2 pcna pcna serpinh1 serpinh1 top2a top2a HMG-1 HMG-1 A0A310U5D8 A0A310U5D8 Vcp.S Vcp.S Serpinh1.L Serpinh1.L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rad50-2Zinc-hook domain-containing protein. (1312 aa)
rad50Zinc-hook domain-containing protein. (1311 aa)
A0A1L8GS29Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
Traip.LRING-type domain-containing protein. (464 aa)
top1.2DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (770 aa)
Znf451.LUncharacterized protein. (1207 aa)
Rbbp8.LUncharacterized protein. (856 aa)
rbbp8Uncharacterized protein. (846 aa)
Tdp2.SEndo/exonuclease/phosphatase domain-containing protein. (382 aa)
Tdp1.LUncharacterized protein. (597 aa)
Sumo1.LUbiquitin-like domain-containing protein. (148 aa)
top1.1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (821 aa)
Brca1.LUncharacterized protein. (1582 aa)
Sumo1.SUbiquitin-like domain-containing protein. (141 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
serpinh1Hsp47-prov protein; Belongs to the serpin family. (419 aa)
top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1579 aa)
HMG-1HMG-1 protein. (210 aa)
A0A310U5D8Rad60-SLD domain-containing protein. (67 aa)
Vcp.SUncharacterized protein; Belongs to the AAA ATPase family. (805 aa)
Serpinh1.LSERPIN domain-containing protein; Belongs to the serpin family. (459 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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