81 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cttn.L	SH3 domain-containing protein. (551 aa)
	mapt	Microtubule-associated protein. (698 aa)
	fscn2	Fascin. (492 aa)
	ntn1	Uncharacterized protein. (602 aa)
	Map2.S	Microtubule-associated protein. (1811 aa)
	fscn1	Fascin. (486 aa)
	ntn3	Uncharacterized protein. (588 aa)
	A0A1L8ESC6	Microtubule-associated protein. (929 aa)
	snph-2	Uncharacterized protein. (438 aa)
	Fscn2.L	Fascin. (492 aa)
	ntn1-2	Uncharacterized protein. (602 aa)
	Map2.L	Microtubule-associated protein. (1769 aa)
	ntn3-2	Uncharacterized protein. (588 aa)
	Cfl2.S	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
	l1cam	Uncharacterized protein. (1251 aa)
	vamp7	Uncharacterized protein; Belongs to the synaptobrevin family. (220 aa)
	nes	IF rod domain-containing protein; Belongs to the intermediate filament family. (1875 aa)
	septin6	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (427 aa)
	cfl2	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
	fmn1	FH2 domain-containing protein. (1393 aa)
	nes-2	IF rod domain-containing protein; Belongs to the intermediate filament family. (1954 aa)
	ntn5	Uncharacterized protein. (601 aa)
	map4	Microtubule-associated protein. (1211 aa)
	A0A1L8FQM4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	Ptk2.S	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1065 aa)
	Map4.L	Microtubule-associated protein. (1234 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (926 aa)
	Sept7.L	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (391 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	Ptk2.L	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1097 aa)
	trim67	Uncharacterized protein. (728 aa)
	A0A1L8G7I3	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	trim67-2	Uncharacterized protein. (522 aa)
	cfl1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
	Cttn.S	SH3 domain-containing protein. (503 aa)
	ckap5	Uncharacterized protein. (2065 aa)
	Cfl1.L	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
	siah1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
	wdr47	Uncharacterized protein. (919 aa)
	A0A1L8GR36	Uncharacterized protein. (902 aa)
	A0A1L8GSX4	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1825 aa)
	Neo1.S	Uncharacterized protein. (1486 aa)
	A0A1L8GTE5	Uncharacterized protein. (2543 aa)
	hcls1	SH3 domain-containing protein. (553 aa)
	sema3a	Uncharacterized protein; Belongs to the semaphorin family. (771 aa)
	Sema3c.S	Uncharacterized protein; Belongs to the semaphorin family. (748 aa)
	Ddx11.L	Helicase ATP-binding domain-containing protein. (898 aa)
	Gria1.L	Uncharacterized protein. (902 aa)
	A0A1L8GXH2	Uncharacterized protein. (2367 aa)
	sema3c	Uncharacterized protein; Belongs to the semaphorin family. (748 aa)
	sema3a-2	Uncharacterized protein; Belongs to the semaphorin family. (774 aa)
	hcls1-2	SH3 domain-containing protein. (554 aa)
	neo1	Uncharacterized protein. (1435 aa)
	A0A1L8H034	Uncharacterized protein. (2543 aa)
	Myo5a.L	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1852 aa)
	myo5c	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1719 aa)
	Vamp2.L	V-SNARE coiled-coil homology domain-containing protein. (238 aa)
	Efnb3.L	Uncharacterized protein. (186 aa)
	trpv2	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (772 aa)
	Efnb2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (329 aa)
	trpv2-2	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (772 aa)
	Alcam.L	Uncharacterized protein. (573 aa)
	Efna5.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	ptch1	SSD domain-containing protein. (1422 aa)
	A0A1L8I2T7	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1809 aa)
	A0A1L8I385	Uncharacterized protein. (2303 aa)
	Tln2.S	Uncharacterized protein. (2612 aa)
	ntn5-2	LOC100127305 protein. (601 aa)
	efnb1	Ephrin-B1 (EPH family ligand); Belongs to the ephrin family. (329 aa)
	src	Tyrosine-protein kinase. (532 aa)
	fscn1-2	Fascin. (484 aa)
	rac1	MGC114731 protein. (192 aa)
	vamp7-2	Sybl1-prov protein; Belongs to the synaptobrevin family. (220 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	alcam	MGC84135 protein. (570 aa)
	siah1-2	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
	efnb2	Efnb2a protein; Belongs to the ephrin family. (329 aa)
	dstn	MGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	ptch1-2	Patched-1. (1418 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ESC6	ckap5	A0A1L8ESC6	A0A1L8GIT7	Microtubule-associated protein.	Uncharacterized protein.	0.846
A0A1L8ESC6	stmn2-2	A0A1L8ESC6	Q6DJD4	Microtubule-associated protein.	Stathmin; Belongs to the stathmin family.	0.415
A0A1L8FQM4	actl6a	A0A1L8FQM4	Q7ZYI5	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Baf53a-pending-prov protein; Belongs to the actin family.	0.489
A0A1L8FQM4	nes	A0A1L8FQM4	A0A1L8F4L7	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.516
A0A1L8FQM4	nes-2	A0A1L8FQM4	A0A1L8FCC8	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.516
A0A1L8FQM4	ntn1	A0A1L8FQM4	A0A1L8EN54	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.521
A0A1L8FQM4	ntn1-2	A0A1L8FQM4	A0A1L8EV13	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.488
A0A1L8FQM4	ntn3	A0A1L8FQM4	A0A1L8EQL7	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.485
A0A1L8FQM4	ntn3-2	A0A1L8FQM4	A0A1L8EY77	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.485
A0A1L8FQM4	ntn5	A0A1L8FQM4	A0A1L8FGS1	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.485
A0A1L8FQM4	ntn5-2	A0A1L8FQM4	A9JS48	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	LOC100127305 protein.	0.485
A0A1L8FQM4	ptch1	A0A1L8FQM4	A0A1L8HYE8	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	SSD domain-containing protein.	0.978
A0A1L8FQM4	ptch1-2	A0A1L8FQM4	Q98SW6	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched-1.	0.999
A0A1L8G7I3	A0A1L8GTE5	A0A1L8G7I3	A0A1L8GTE5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.510
A0A1L8G7I3	A0A1L8H034	A0A1L8G7I3	A0A1L8H034	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.509
A0A1L8G7I3	A0A1L8I385	A0A1L8G7I3	A0A1L8I385	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.509
A0A1L8G7I3	Cfl1.L	A0A1L8G7I3	A0A1L8GJZ1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.408
A0A1L8G7I3	Cttn.L	A0A1L8G7I3	A0A1L8GIU7	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	SH3 domain-containing protein.	0.719
A0A1L8G7I3	Cttn.S	A0A1L8G7I3	A0A1L8GE11	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	SH3 domain-containing protein.	0.719
A0A1L8G7I3	Fscn2.L	A0A1L8G7I3	A0A1L8ETI6	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Fascin.	0.549