36 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wls	Uncharacterized protein. (541 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	hspa1l	Hsc70 protein; Belongs to the heat shock protein 70 family. (650 aa)
	cd63-2	Tetraspanin. (238 aa)
	cd63	Tetraspanin. (240 aa)
	sdcbp	MGC81274 protein. (295 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Smo.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
	Smo.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
	Wls.L	Uncharacterized protein. (541 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	Pou5f3.1	POU domain protein. (445 aa)
	pou5f3.2	POU domain protein. (449 aa)
	prkg1	cGMP-dependent protein kinase. (673 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	Hspa8.L	Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	Fzd6.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
	pxdn	Uncharacterized protein. (1461 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	pxdn-2	Uncharacterized protein. (1464 aa)
	Cd81.S	Tetraspanin. (237 aa)
	Cd81.L	Tetraspanin. (258 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd81.L	cd63	A0A1L8GJ51	Q6DCP2	Tetraspanin.	Tetraspanin.	0.709
Cd81.L	cd63-2	A0A1L8GJ51	Q7SY95	Tetraspanin.	Tetraspanin.	0.711
Cd81.L	sdcbp	A0A1L8GJ51	Q66JA3	Tetraspanin.	MGC81274 protein.	0.592
Cd81.S	cd63	A0A1L8GDC4	Q6DCP2	Tetraspanin.	Tetraspanin.	0.676
Cd81.S	cd63-2	A0A1L8GDC4	Q7SY95	Tetraspanin.	Tetraspanin.	0.677
Cd81.S	sdcbp	A0A1L8GDC4	Q66JA3	Tetraspanin.	MGC81274 protein.	0.592
Fzd6.S	Fzd8.L	A0A1L8FTP5	A0A1L8FVD0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.472
Fzd6.S	Lrp5.L	A0A1L8FTP5	A0A1L8GJX4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.967
Fzd6.S	Wnt1.L	A0A1L8FTP5	A0A1L8HHR8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.935
Fzd6.S	ctnnb1	A0A1L8FTP5	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.803
Fzd6.S	dkk1	A0A1L8FTP5	A0A1L8FIS6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf_N domain-containing protein.	0.447
Fzd6.S	dkk1-2	A0A1L8FTP5	O57464	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf homolog 1.	0.448
Fzd6.S	fz3	A0A1L8FTP5	B7ZQS8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.582
Fzd6.S	fzd1	A0A1L8FTP5	A0A1L8FVQ7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.445
Fzd6.S	fzd2	A0A1L8FTP5	A0A1L8EL29	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.445
Fzd6.S	fzd3	A0A1L8FTP5	A0A1L8G5I1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.581
Fzd6.S	fzd5	A0A1L8FTP5	A0A1L8EPX2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.474
Fzd6.S	fzd7	A0A1L8FTP5	A0A1L8EX17	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.450
Fzd6.S	wnt1	A0A1L8FTP5	A0A1L8H9S8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.935
Fzd6.S	wnt4	A0A1L8FTP5	A0A1L8FG99	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.975