40 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	acin1	Uncharacterized protein. (2021 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	psmd14	Psmd14-prov protein. (310 aa)
	top2a	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1579 aa)
	rnf4	LOC495944 protein. (190 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	psmb5-2	Proteasome subunit beta. (257 aa)
	Rnf4-a	RING-type domain-containing protein. (190 aa)
	psmb5	Proteasome subunit beta. (257 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	ube2i	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	top1.1	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (821 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	Uba1.S	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1044 aa)
	entpd2	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (601 aa)
	entpd2-2	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (500 aa)
	mdc1	Uncharacterized protein. (2103 aa)
	sae1	ThiF domain-containing protein. (344 aa)
	Tdp1.L	Uncharacterized protein. (597 aa)
	tpi1	Triosephosphate isomerase. (248 aa)
	tpi1-2	Triosephosphate isomerase. (248 aa)
	Tdp2.S	Endo/exonuclease/phosphatase domain-containing protein. (382 aa)
	rbbp8	Uncharacterized protein. (846 aa)
	Rbbp8.L	Uncharacterized protein. (856 aa)
	Prkdc.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4146 aa)
	Nsmce2.L	SP-RING-type domain-containing protein. (238 aa)
	sprtn	Uncharacterized protein. (565 aa)
	top1.2	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (770 aa)
	bbs1	BBS1 domain-containing protein. (588 aa)
	Rad52.S	Uncharacterized protein. (429 aa)
	pias1	Uncharacterized protein. (640 aa)
	Rnf111-b	RNF111_N domain-containing protein. (921 aa)
	rnf111	RING-type domain-containing protein. (975 aa)
	Pias1.L	Uncharacterized protein. (649 aa)
	Sim2.S	Uncharacterized protein. (760 aa)
	sim2	Uncharacterized protein. (761 aa)
	Alb.S	Uncharacterized protein. (607 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alb.S	Gapdh.S	A0A1L8HMG9	Q7ZY52	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Alb.S	gapdh	A0A1L8HMG9	Q8AY70	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Brca1.L	Gapdh.S	A0A1L8ETS4	Q7ZY52	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.495
Brca1.L	Pias1.L	A0A1L8ETS4	A0A1L8H180	Uncharacterized protein.	Uncharacterized protein.	0.698
Brca1.L	Prkdc.L	A0A1L8ETS4	A0A1L8FYZ4	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.903
Brca1.L	Rad52.S	A0A1L8ETS4	A0A1L8GQQ7	Uncharacterized protein.	Uncharacterized protein.	0.984
Brca1.L	Rbbp8.L	A0A1L8ETS4	A0A1L8FYP2	Uncharacterized protein.	Uncharacterized protein.	0.999
Brca1.L	Rnf4-a	A0A1L8ETS4	A0A1L8HT51	Uncharacterized protein.	RING-type domain-containing protein.	0.534
Brca1.L	Sumo1.L	A0A1L8ETS4	A0A1L8EWZ5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.712
Brca1.L	Sumo1.S	A0A1L8ETS4	A0A1L8EPQ0	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.712
Brca1.L	Tdp1.L	A0A1L8ETS4	A0A1L8F9F5	Uncharacterized protein.	Uncharacterized protein.	0.628
Brca1.L	Tdp2.S	A0A1L8ETS4	A0A1L8FSF5	Uncharacterized protein.	Endo/exonuclease/phosphatase domain-containing protein.	0.533
Brca1.L	Uba1.S	A0A1L8ETS4	A0A1L8EZK6	Uncharacterized protein.	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.	0.548
Brca1.L	gapdh	A0A1L8ETS4	Q8AY70	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.495
Brca1.L	mdc1	A0A1L8ETS4	A0A1L8F8K7	Uncharacterized protein.	Uncharacterized protein.	0.975
Brca1.L	pias1	A0A1L8ETS4	A0A1L8GSB5	Uncharacterized protein.	Uncharacterized protein.	0.698
Brca1.L	psmd14	A0A1L8ETS4	Q7ZX92	Uncharacterized protein.	Psmd14-prov protein.	0.497
Brca1.L	rbbp8	A0A1L8ETS4	A0A1L8FSU5	Uncharacterized protein.	Uncharacterized protein.	0.999
Brca1.L	rnf4	A0A1L8ETS4	Q5PQ91	Uncharacterized protein.	LOC495944 protein.	0.534
Brca1.L	sumo2	A0A1L8ETS4	A0A1L8EMU2	Uncharacterized protein.	Small ubiquitin-related modifier.	0.752