65 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	trabd	Uncharacterized protein. (367 aa)
	rac3	RAC1 protein. (192 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	sfrp2-2	Sfrp2-prov protein. (298 aa)
	got1	Aspartate aminotransferase. (411 aa)
	rhoa	MGC64296 protein. (193 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	gpc4-2	Xgly4 protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
	rac1	MGC114731 protein. (192 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	tcf7l1-2	Transcription factor XTCF-3b. (554 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	znrf3	RING-type domain-containing protein. (854 aa)
	kremen1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
	A0A1L8HXI8	Uncharacterized protein. (510 aa)
	sfrp2	Uncharacterized protein. (295 aa)
	Znrf3.S	RING-type domain-containing protein. (848 aa)
	Kremen1.S	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
	tnks	Poly [ADP-ribose] polymerase. (1298 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	rspo1	Uncharacterized protein. (257 aa)
	Bcl9.L	BCL9 domain-containing protein. (1387 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	rnf43	RING-type domain-containing protein. (664 aa)
	bcl9	BCL9 domain-containing protein. (1473 aa)
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	Trabd.L	Uncharacterized protein. (373 aa)
	Lgr5.L	G_PROTEIN_RECEP_F1_2 domain-containing protein. (902 aa)
	wif1	Uncharacterized protein. (374 aa)
	lgr5	G_PROTEIN_RECEP_F1_2 domain-containing protein. (902 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	usp7	Uncharacterized protein; Belongs to the peptidase C19 family. (1123 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	usp7-2	Usp7; Belongs to the peptidase C19 family. (1124 aa)
	axin1	Uncharacterized protein. (841 aa)
	gpc4	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (549 aa)
	tnks2	Poly [ADP-ribose] polymerase. (1165 aa)
	Tcf7l2.L	HMG box domain-containing protein. (482 aa)
	bcl9l	BCL9 domain-containing protein. (1281 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	rspo3	Uncharacterized protein. (253 aa)
	A0A1L8GA74	Uncharacterized protein. (1480 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Lgr4.S	G_PROTEIN_RECEP_F1_2 domain-containing protein. (956 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	got2	Aspartate aminotransferase. (427 aa)
	ep300	Uncharacterized protein. (2495 aa)
	lgr4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (953 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Got2.L	Aspartate aminotransferase. (427 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	ep300-2	Uncharacterized protein. (2492 aa)
	tcf7l1	HMG box domain-containing protein. (551 aa)
	pclaf	PAF domain-containing protein. (123 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GA74	Tcf7l2.L	A0A1L8GA74	A0A1L8FI38	Uncharacterized protein.	HMG box domain-containing protein.	0.435
A0A1L8GA74	Trabd.L	A0A1L8GA74	A0A1L8GZ03	Uncharacterized protein.	Uncharacterized protein.	0.474
A0A1L8GA74	tcf7l1	A0A1L8GA74	A0A1L8GRU8	Uncharacterized protein.	HMG box domain-containing protein.	0.559
A0A1L8GA74	tcf7l1-2	A0A1L8GA74	B7ZQ53	Uncharacterized protein.	Transcription factor XTCF-3b.	0.559
A0A1L8GA74	trabd	A0A1L8GA74	A0A1L8GU28	Uncharacterized protein.	Uncharacterized protein.	0.474
A0A1L8HXI8	Trabd.L	A0A1L8HXI8	A0A1L8GZ03	Uncharacterized protein.	Uncharacterized protein.	0.830
A0A1L8HXI8	trabd	A0A1L8HXI8	A0A1L8GU28	Uncharacterized protein.	Uncharacterized protein.	0.830
Axin1.S	Bcl9.L	A0A1L8ER48	A0A1L8HC43	Uncharacterized protein.	BCL9 domain-containing protein.	0.681
Axin1.S	Cdh3.S	A0A1L8ER48	A0A1L8GET9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.796
Axin1.S	Fzd4.S	A0A1L8ER48	A0A1L8HB90	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.683
Axin1.S	Fzd8.L	A0A1L8ER48	A0A1L8FVD0	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.670
Axin1.S	Jun.L	A0A1L8ER48	A0A1L8GLZ4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.710
Axin1.S	Lgr4.S	A0A1L8ER48	A0A1L8GDQ5	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.597
Axin1.S	Lgr5.L	A0A1L8ER48	A0A1L8GYN0	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.583
Axin1.S	Lrp5.L	A0A1L8ER48	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.998
Axin1.S	Tcf7l2.L	A0A1L8ER48	A0A1L8FI38	Uncharacterized protein.	HMG box domain-containing protein.	0.689
Axin1.S	Wnt1.L	A0A1L8ER48	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.931
Axin1.S	Znrf3.S	A0A1L8ER48	A0A1L8HQY2	Uncharacterized protein.	RING-type domain-containing protein.	0.668
Axin1.S	bcl9	A0A1L8ER48	A0A1L8H5D8	Uncharacterized protein.	BCL9 domain-containing protein.	0.681
Axin1.S	c-Jun	A0A1L8ER48	Q9PVZ1	Uncharacterized protein.	C-Jun protein; Belongs to the bZIP family.	0.710