21 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stk11-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	Nr1h5.S	Uncharacterized protein. (530 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	stk11	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	stk24-2	MGC80614 protein. (424 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	src	Tyrosine-protein kinase. (532 aa)
	NumbL	PID domain-containing protein. (588 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	A0A1L8EZU6	PID domain-containing protein. (642 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	Aurka.S	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (408 aa)
	stk24	Protein kinase domain-containing protein. (425 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	pard3-2	Uncharacterized protein. (1332 aa)
	pard3	Uncharacterized protein. (1369 aa)
	numbl	PID domain-containing protein. (651 aa)
	A0A1L8F8U7	PID domain-containing protein. (588 aa)
	notch1	Uncharacterized protein. (2521 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYQ3	A0A1L8EZU6	A0A1L8EYQ3	A0A1L8EZU6	LLGL domain-containing protein.	PID domain-containing protein.	0.542
A0A1L8EYQ3	A0A1L8F8U7	A0A1L8EYQ3	A0A1L8F8U7	LLGL domain-containing protein.	PID domain-containing protein.	0.542
A0A1L8EYQ3	Cdh3.S	A0A1L8EYQ3	A0A1L8GET9	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.479
A0A1L8EYQ3	NumbL	A0A1L8EYQ3	A0A1L8F3U1	LLGL domain-containing protein.	PID domain-containing protein.	0.542
A0A1L8EYQ3	Prkci.L	A0A1L8EYQ3	A0A1L8GAK2	LLGL domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.992
A0A1L8EYQ3	cdh1	A0A1L8EYQ3	A0A1L8GKV4	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.428
A0A1L8EYQ3	cdh3	A0A1L8EYQ3	A0A1L8GKW6	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.473
A0A1L8EYQ3	numbl	A0A1L8EYQ3	A0A1L8FAF0	LLGL domain-containing protein.	PID domain-containing protein.	0.539
A0A1L8EZU6	A0A1L8EYQ3	A0A1L8EZU6	A0A1L8EYQ3	PID domain-containing protein.	LLGL domain-containing protein.	0.542
A0A1L8EZU6	Aurka.S	A0A1L8EZU6	A0A1L8ELH7	PID domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.419
A0A1L8EZU6	Notch1.S	A0A1L8EZU6	A0A1L8F124	PID domain-containing protein.	Uncharacterized protein.	0.942
A0A1L8EZU6	Prkci.L	A0A1L8EZU6	A0A1L8GAK2	PID domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.822
A0A1L8EZU6	cdh3	A0A1L8EZU6	A0A1L8GKW6	PID domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.426
A0A1L8EZU6	ctnnb1	A0A1L8EZU6	Q63ZT4	PID domain-containing protein.	Beta-catenin protein.	0.478
A0A1L8EZU6	notch1	A0A1L8EZU6	A0A1L8F627	PID domain-containing protein.	Uncharacterized protein.	0.942
A0A1L8EZU6	pard3	A0A1L8EZU6	A0A1L8FQM3	PID domain-containing protein.	Uncharacterized protein.	0.587
A0A1L8EZU6	pard3-2	A0A1L8EZU6	A0A1L8FVE8	PID domain-containing protein.	Uncharacterized protein.	0.539
A0A1L8F8U7	A0A1L8EYQ3	A0A1L8F8U7	A0A1L8EYQ3	PID domain-containing protein.	LLGL domain-containing protein.	0.542
A0A1L8F8U7	Aurka.S	A0A1L8F8U7	A0A1L8ELH7	PID domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.419
A0A1L8F8U7	Notch1.S	A0A1L8F8U7	A0A1L8F124	PID domain-containing protein.	Uncharacterized protein.	0.943