53 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pard6g-2	MGC80569 protein. (384 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	hdac1-2	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa)
	pard6b	Uncharacterized protein. (377 aa)
	llgl2	WD_REPEATS_REGION domain-containing protein. (1019 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	Llgl2.L	WD_REPEATS_REGION domain-containing protein. (1017 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	A0A1L8EZU6	PID domain-containing protein. (642 aa)
	crb2	Uncharacterized protein. (1472 aa)
	NumbL	PID domain-containing protein. (588 aa)
	F11r.S	Uncharacterized protein. (289 aa)
	Crb2.L	Uncharacterized protein. (1120 aa)
	A0A1L8F8U7	PID domain-containing protein. (588 aa)
	numbl	PID domain-containing protein. (651 aa)
	A0A1L8FQM4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	Zeb1.S	Uncharacterized protein. (919 aa)
	pard6g	Uncharacterized protein. (384 aa)
	dsc3	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (898 aa)
	stxbp5	Uncharacterized protein. (1152 aa)
	stxbp5-2	Uncharacterized protein. (1146 aa)
	dynlt1	Uncharacterized protein. (113 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	Cttn.S	SH3 domain-containing protein. (503 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	Cttn.L	SH3 domain-containing protein. (551 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	A0A1L8GQA4	Uncharacterized protein. (760 aa)
	hcls1	SH3 domain-containing protein. (553 aa)
	Smo.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
	Pkp2.L	Uncharacterized protein. (736 aa)
	Gria1.L	Uncharacterized protein. (902 aa)
	Kif3a.L	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (669 aa)
	Smo.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
	hcls1-2	SH3 domain-containing protein. (554 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	A0A1L8H5U5	Uncharacterized protein. (1181 aa)
	Pkp1.S	Uncharacterized protein. (742 aa)
	A0A1L8HBW6	Uncharacterized protein. (1186 aa)
	Pkp1.L	Uncharacterized protein. (774 aa)
	hdac1	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa)
	stk11	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	stk11-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	Tjp2.L	Uncharacterized protein. (430 aa)
	Mapk1.L	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	pten	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	src	Tyrosine-protein kinase. (532 aa)
	f11r	LOC398627 protein. (291 aa)
	rhoa	MGC64296 protein. (193 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYQ3	A0A1L8EZU6	A0A1L8EYQ3	A0A1L8EZU6	LLGL domain-containing protein.	PID domain-containing protein.	0.542
A0A1L8EYQ3	A0A1L8F8U7	A0A1L8EYQ3	A0A1L8F8U7	LLGL domain-containing protein.	PID domain-containing protein.	0.542
A0A1L8EYQ3	Cdh3.S	A0A1L8EYQ3	A0A1L8GET9	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.479
A0A1L8EYQ3	Llgl2.L	A0A1L8EYQ3	A0A1L8EUD8	LLGL domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.733
A0A1L8EYQ3	NumbL	A0A1L8EYQ3	A0A1L8F3U1	LLGL domain-containing protein.	PID domain-containing protein.	0.542
A0A1L8EYQ3	Prkci.L	A0A1L8EYQ3	A0A1L8GAK2	LLGL domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.992
A0A1L8EYQ3	actl6a	A0A1L8EYQ3	Q7ZYI5	LLGL domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.439
A0A1L8EYQ3	cdh1	A0A1L8EYQ3	A0A1L8GKV4	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.428
A0A1L8EYQ3	cdh11-2	A0A1L8EYQ3	O93264	LLGL domain-containing protein.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.437
A0A1L8EYQ3	cdh3	A0A1L8EYQ3	A0A1L8GKW6	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.473
A0A1L8EYQ3	llgl2	A0A1L8EYQ3	A0A1L8EMV4	LLGL domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.733
A0A1L8EYQ3	numbl	A0A1L8EYQ3	A0A1L8FAF0	LLGL domain-containing protein.	PID domain-containing protein.	0.539
A0A1L8EYQ3	pard6b	A0A1L8EYQ3	A0A1L8ELH2	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	pard6b-2	A0A1L8EYQ3	A0A1L8ESP6	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	pard6g	A0A1L8EYQ3	A0A1L8FY89	LLGL domain-containing protein.	Uncharacterized protein.	0.716
A0A1L8EYQ3	pard6g-2	A0A1L8EYQ3	Q6GPA4	LLGL domain-containing protein.	MGC80569 protein.	0.716
A0A1L8EZU6	A0A1L8EYQ3	A0A1L8EZU6	A0A1L8EYQ3	PID domain-containing protein.	LLGL domain-containing protein.	0.542
A0A1L8EZU6	Prkci.L	A0A1L8EZU6	A0A1L8GAK2	PID domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.822
A0A1L8EZU6	Tp53.L	A0A1L8EZU6	A0A1L8H4M6	PID domain-containing protein.	P53 domain-containing protein.	0.613
A0A1L8EZU6	actl6a	A0A1L8EZU6	Q7ZYI5	PID domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.406