STRINGSTRING
A0A1L8HYG4 A0A1L8HYG4 fzd2 fzd2 bmp7.1 bmp7.1 Nfatc2.S Nfatc2.S A0A1L8ENI4 A0A1L8ENI4 wnt10a wnt10a Fn1.S Fn1.S fzd5 fzd5 Axin1.S Axin1.S nfatc2 nfatc2 A0A1L8EUY4 A0A1L8EUY4 wnt6 wnt6 fzd7 fzd7 axin1 axin1 akt1 akt1 A0A1L8F260 A0A1L8F260 A0A1L8F665 A0A1L8F665 wnt11b wnt11b wnt4 wnt4 Tcf7l2.L Tcf7l2.L Phb2.L Phb2.L dvl1 dvl1 wnt4-2 wnt4-2 A0A1L8FND1 A0A1L8FND1 A0A1L8FNJ4 A0A1L8FNJ4 axin2 axin2 tfap2a tfap2a Rock1.S Rock1.S Fzd6.S Fzd6.S Fzd8.L Fzd8.L fzd1 fzd1 igf2bp3 igf2bp3 ezh2 ezh2 Tfap2a.L Tfap2a.L Rock1.L Rock1.L snai2 snai2 fzd6 fzd6 bmp2 bmp2 col10a1 col10a1 rock2 rock2 Bmp2.L Bmp2.L A0A1L8G7B1 A0A1L8G7B1 mkks mkks ryk ryk Rock2.L Rock2.L ins ins Slc1a2.S Slc1a2.S fgf3 fgf3 Cdh3.S Cdh3.S Slc1a7.S Slc1a7.S rgs18 rgs18 mcm2 mcm2 slc1a2 slc1a2 bbs1 bbs1 nfatc3 nfatc3 rbl2 rbl2 cdh1 cdh1 cdh3 cdh3 Jun.L Jun.L slc1a7 slc1a7 Grin2b.L Grin2b.L Rho.L Rho.L Mcm2.L Mcm2.L Wnt5b.S Wnt5b.S Gata3.L Gata3.L Bmp7.2.L Bmp7.2.L il10 il10 wnt1 wnt1 aqp5 aqp5 Mmp13.S Mmp13.S Mmp13l.S Mmp13l.S Fzd4.S Fzd4.S il10-2 il10-2 Wnt1.L Wnt1.L wnt10b wnt10b col2a1 col2a1 Yap1.L Yap1.L Mmp3.L Mmp3.L mmp13l mmp13l wnt11 wnt11 Vegfc.S Vegfc.S A0A1L8HNG2 A0A1L8HNG2 A0A1L8HRR7 A0A1L8HRR7 vegfc vegfc A0A1L8HWT0 A0A1L8HWT0 A0A1L8HWZ5 A0A1L8HWZ5 slc1a3 slc1a3 Igf2bp3.S Igf2bp3.S slc1a5 slc1a5 nkx6-1 nkx6-1 grin2b grin2b fos fos wnt6-2 wnt6-2 nf-at nf-at Xwnt-8b Xwnt-8b ins-2 ins-2 wnt10a-2 wnt10a-2 xfz8 xfz8 mespa mespa sox9-a sox9-a wnt7b wnt7b cdh11-2 cdh11-2 src src gata3 gata3 rac1 rac1 ctnnb1 ctnnb1 axin2-2 axin2-2 fos-2 fos-2 prkca prkca phb2 phb2 Xporc-d Xporc-d rgs18-2 rgs18-2 myc myc rhoa rhoa actl6a actl6a ccnd1 ccnd1 snai2-2 snai2-2 pcna pcna c-Jun c-Jun rac3 rac3 bmp7.1-2 bmp7.1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L8HYG4Amino acid transporter. (681 aa)
fzd2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
bmp7.1TGF_BETA_2 domain-containing protein. (424 aa)
Nfatc2.SRHD domain-containing protein. (884 aa)
A0A1L8ENI4Uncharacterized protein. (815 aa)
wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
Fn1.SUncharacterized protein. (2480 aa)
fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
Axin1.SUncharacterized protein. (839 aa)
nfatc2RHD domain-containing protein. (896 aa)
A0A1L8EUY4Uncharacterized protein. (818 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
fzd7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
axin1Uncharacterized protein. (841 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
A0A1L8F260TIR domain-containing protein; Belongs to the Toll-like receptor family. (840 aa)
A0A1L8F665Uncharacterized protein. (1071 aa)
wnt11bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Tcf7l2.LHMG box domain-containing protein. (482 aa)
Phb2.LProhibitin. (347 aa)
dvl1Uncharacterized protein. (606 aa)
wnt4-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
A0A1L8FND1IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
A0A1L8FNJ4Amino acid transporter. (557 aa)
axin2Uncharacterized protein. (707 aa)
tfap2aTF_AP-2 domain-containing protein. (470 aa)
Rock1.SRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
Fzd6.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
Fzd8.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
fzd1Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
igf2bp3Uncharacterized protein. (594 aa)
ezh2Uncharacterized protein. (748 aa)
Tfap2a.LTF_AP-2 domain-containing protein. (472 aa)
Rock1.LRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
snai2Uncharacterized protein. (266 aa)
fzd6Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
bmp2TGF_BETA_2 domain-containing protein. (398 aa)
col10a1C1q domain-containing protein. (668 aa)
rock2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1399 aa)
Bmp2.LTGF_BETA_2 domain-containing protein. (398 aa)
A0A1L8G7B1Amino acid transporter. (537 aa)
mkksUncharacterized protein. (572 aa)
rykUncharacterized protein. (596 aa)
Rock2.LRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
Slc1a2.SAmino acid transporter. (503 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
Cdh3.SUncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
Slc1a7.SAmino acid transporter. (520 aa)
rgs18RGS domain-containing protein. (163 aa)
mcm2DNA helicase; Belongs to the MCM family. (885 aa)
slc1a2Amino acid transporter. (568 aa)
bbs1BBS1 domain-containing protein. (588 aa)
nfatc3RHD domain-containing protein. (885 aa)
rbl2Uncharacterized protein. (1087 aa)
cdh1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
cdh3Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
slc1a7Amino acid transporter. (564 aa)
Grin2b.LUncharacterized protein. (1449 aa)
Rho.LRhodopsin. (459 aa)
Mcm2.LDNA helicase; Belongs to the MCM family. (886 aa)
Wnt5b.SProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
Gata3.LUncharacterized protein. (454 aa)
Bmp7.2.LTGF_BETA_2 domain-containing protein. (438 aa)
il10Uncharacterized protein. (172 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
aqp5Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (279 aa)
Mmp13.SZnMc domain-containing protein. (258 aa)
Mmp13l.SZnMc domain-containing protein. (472 aa)
Fzd4.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
il10-2Uncharacterized protein. (170 aa)
Wnt1.LProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
col2a1Uncharacterized protein. (1486 aa)
Yap1.LUncharacterized protein. (459 aa)
Mmp3.LZnMc domain-containing protein. (503 aa)
mmp13lZnMc domain-containing protein. (472 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Vegfc.SPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (407 aa)
A0A1L8HNG2Amino acid transporter. (564 aa)
A0A1L8HRR7Amino acid transporter. (542 aa)
vegfcPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (402 aa)
A0A1L8HWT0Amino acid transporter. (562 aa)
A0A1L8HWZ5Amino acid transporter. (471 aa)
slc1a3Amino acid transporter. (592 aa)
Igf2bp3.SUncharacterized protein. (593 aa)
slc1a5Amino acid transporter. (527 aa)
nkx6-1NK6 transcription factor related locus 1. (351 aa)
grin2bGlutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B sub [...] (1448 aa)
fosBZIP domain-containing protein. (369 aa)
wnt6-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
nf-atNuclear factor of activated T-cell. (884 aa)
Xwnt-8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
ins-2Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
wnt10a-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
xfz8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
mespaBHLH transcription factor mespa. (283 aa)
sox9-aSex determining region Y-box 9. (477 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
cdh11-2Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
srcTyrosine-protein kinase. (532 aa)
gata3XGATA-3 protein. (435 aa)
rac1MGC114731 protein. (192 aa)
ctnnb1Beta-catenin protein. (781 aa)
axin2-2MGC81576 protein. (707 aa)
fos-2MGC80305 protein. (368 aa)
prkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
phb2Prohibitin. (301 aa)
Xporc-dXporc-d protein; Belongs to the membrane-bound acyltransferase family. (450 aa)
rgs18-2MGC80762 protein. (236 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
rhoaMGC64296 protein. (193 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
ccnd1Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
snai2-2Zinc finger transcription factor slug beta. (266 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
rac3RAC1 protein. (192 aa)
bmp7.1-2Osteogenic protein-1 homolog. (424 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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