STRINGSTRING
tcf7l1-2 tcf7l1-2 ror2 ror2 tbx5 tbx5 pcdh10-2 pcdh10-2 Egf.L Egf.L A0A1L8I1D3 A0A1L8I1D3 fgf10 fgf10 nkx6-1 nkx6-1 fgf10-2 fgf10-2 nodal2 nodal2 foxf1 foxf1 bmp4 bmp4 nog nog tbx5-2 tbx5-2 sox9-a sox9-a wnt7b wnt7b nodal6 nodal6 Xnr5-3 Xnr5-3 tagln tagln ctnnb1 ctnnb1 gata4-2 gata4-2 tbxt-2 tbxt-2 acta2 acta2 tagln2-2 tagln2-2 ctnnb1-2 ctnnb1-2 actl6a actl6a ror2-2 ror2-2 lef1-2 lef1-2 bmp4-2 bmp4-2 tcea1 tcea1 nodal6-2 nodal6-2 nodal5.2 nodal5.2 bmp7.1-2 bmp7.1-2 bmp7.1 bmp7.1 foxj1 foxj1 rdh20 rdh20 Foxj1.L Foxj1.L foxj1.2 foxj1.2 Notch1.S Notch1.S tgfb1 tgfb1 notch1 notch1 tgfb1-2 tgfb1-2 Nkx2-1.L Nkx2-1.L tagln2 tagln2 fgfr2 fgfr2 nodal nodal Tcf7l2.L Tcf7l2.L fgfr2-2 fgfr2-2 Nodal.L Nodal.L Tagln.L Tagln.L Vim.S Vim.S gli3 gli3 Sox17a.S Sox17a.S sox17b.1 sox17b.1 Rdh10.S Rdh10.S Shh.L Shh.L Vim.L Vim.L gli3-2 gli3-2 sox17b.1-2 sox17b.1-2 srf srf tbxt tbxt tbxt.2 tbxt.2 tp63 tp63 kcnj13 kcnj13 gata4 gata4 srf-2 srf-2 Foxa2.L Foxa2.L tp63-2 tp63-2 Kcnj13.L Kcnj13.L Cldn18.L Cldn18.L Ano1.L Ano1.L A0A1L8GRI1 A0A1L8GRI1 fgfr1 fgfr1 Xnr2 Xnr2 sfrp1 sfrp1 tcf7l1 tcf7l1 pax8 pax8 cftr cftr Ascl1.L Ascl1.L cftr-2 cftr-2 Bmp7.2.L Bmp7.2.L pax8-2 pax8-2 Sfrp1.L Sfrp1.L nodal5 nodal5 fgfr1-2 fgfr1-2 Xnr5-6 Xnr5-6 A0A1L8H2D1 A0A1L8H2D1 A0A1L8H2D6 A0A1L8H2D6 Nodal3.2.L Nodal3.2.L nodal1 nodal1 A0A1L8H2G3 A0A1L8H2G3 sox21 sox21 tbx4 tbx4 pcdh10 pcdh10 lef1 lef1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tcf7l1-2Transcription factor XTCF-3b. (554 aa)
ror2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
tbx5Uncharacterized protein. (519 aa)
pcdh10-2Uncharacterized protein. (1010 aa)
Egf.LUncharacterized protein. (1031 aa)
A0A1L8I1D3Uncharacterized protein. (2898 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
nkx6-1NK6 transcription factor related locus 1. (351 aa)
fgf10-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
nodal2Xnr-2. (405 aa)
foxf1XFD-13 protein. (373 aa)
bmp4Bone morphogenetic protein 4. (401 aa)
nogNoggin; Belongs to the noggin family. (222 aa)
tbx5-2T-box transcription factor Tbx5. (519 aa)
sox9-aSex determining region Y-box 9. (477 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
nodal6Xnr6b protein. (379 aa)
Xnr5-3Xnr5-3. (386 aa)
taglnTransgelin; Belongs to the calponin family. (201 aa)
ctnnb1Beta-catenin protein. (781 aa)
gata4-2MGC81427 protein. (394 aa)
tbxt-2MGC81453 protein. (432 aa)
acta2MGC78870 protein. (377 aa)
tagln2-2Transgelin; Belongs to the calponin family. (197 aa)
ctnnb1-2Ctnnb1-prov protein. (781 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
ror2-2Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
lef1-2Lymphoid enhancer factor XLEF-1. (372 aa)
bmp4-2Bone morphogenetic protein 4. (400 aa)
tcea1TFIIS elongation factor. (303 aa)
nodal6-2Xnr6. (378 aa)
nodal5.2Xnr5-10. (384 aa)
bmp7.1-2Osteogenic protein-1 homolog. (424 aa)
bmp7.1TGF_BETA_2 domain-containing protein. (424 aa)
foxj1Fork-head domain-containing protein. (439 aa)
rdh20Uncharacterized protein. (307 aa)
Foxj1.LFork-head domain-containing protein. (495 aa)
foxj1.2Fork-head domain-containing protein. (402 aa)
Notch1.SUncharacterized protein. (2524 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
notch1Uncharacterized protein. (2521 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
Nkx2-1.LHomeobox domain-containing protein. (347 aa)
tagln2Transgelin; Belongs to the calponin family. (197 aa)
fgfr2Fibroblast growth factor receptor. (830 aa)
nodalTGF_BETA_2 domain-containing protein. (402 aa)
Tcf7l2.LHMG box domain-containing protein. (482 aa)
fgfr2-2Fibroblast growth factor receptor. (832 aa)
Nodal.LTGF_BETA_2 domain-containing protein. (402 aa)
Tagln.LTransgelin; Belongs to the calponin family. (200 aa)
Vim.SIF rod domain-containing protein; Belongs to the intermediate filament family. (463 aa)
gli3Uncharacterized protein. (1565 aa)
Sox17a.SUncharacterized protein. (377 aa)
sox17b.1Uncharacterized protein. (373 aa)
Rdh10.SUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
Shh.LHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
Vim.LIF rod domain-containing protein; Belongs to the intermediate filament family. (458 aa)
gli3-2Uncharacterized protein. (1568 aa)
sox17b.1-2Uncharacterized protein. (373 aa)
srfMADS-box domain-containing protein. (449 aa)
tbxtUncharacterized protein. (432 aa)
tbxt.2Uncharacterized protein. (434 aa)
tp63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
kcnj13Uncharacterized protein. (374 aa)
gata4Uncharacterized protein. (392 aa)
srf-2MADS-box domain-containing protein. (448 aa)
Foxa2.LFork-head domain-containing protein. (434 aa)
tp63-2Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (636 aa)
Kcnj13.LUncharacterized protein. (374 aa)
Cldn18.LClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (367 aa)
Ano1.LAnoctamin. (976 aa)
A0A1L8GRI1TGF_BETA_2 domain-containing protein. (406 aa)
fgfr1Fibroblast growth factor receptor. (810 aa)
Xnr2TGF_BETA_2 domain-containing protein. (405 aa)
sfrp1Uncharacterized protein. (311 aa)
tcf7l1HMG box domain-containing protein. (551 aa)
pax8Paired domain-containing protein. (467 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
Ascl1.LBHLH domain-containing protein. (242 aa)
cftr-2Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
Bmp7.2.LTGF_BETA_2 domain-containing protein. (438 aa)
pax8-2Paired domain-containing protein. (465 aa)
Sfrp1.LUncharacterized protein. (311 aa)
nodal5TGF_BETA_2 domain-containing protein. (384 aa)
fgfr1-2Fibroblast growth factor receptor. (812 aa)
Xnr5-6TGF_BETA_2 domain-containing protein. (386 aa)
A0A1L8H2D1TGF_BETA_2 domain-containing protein. (401 aa)
A0A1L8H2D6TGF_BETA_2 domain-containing protein. (348 aa)
Nodal3.2.LTGF_BETA_2 domain-containing protein. (401 aa)
nodal1TGF_BETA_2 domain-containing protein. (406 aa)
A0A1L8H2G3TGF_BETA_2 domain-containing protein. (401 aa)
sox21HMG box domain-containing protein. (262 aa)
tbx4Uncharacterized protein. (541 aa)
pcdh10Uncharacterized protein. (1011 aa)
lef1HMG box domain-containing protein. (372 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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