21 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Daxx.L	Daxx domain-containing protein. (911 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	sympk	Uncharacterized protein. (1202 aa)
	Eif4g2.S	Uncharacterized protein. (908 aa)
	htatip2	NAD(P)-bd_dom domain-containing protein. (270 aa)
	Nat1	Uncharacterized protein. (1006 aa)
	sec61a1	Plug_translocon domain-containing protein. (476 aa)
	nr3c1	Uncharacterized protein. (761 aa)
	Hdac3.S	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (405 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (830 aa)
	Pias4.S	Uncharacterized protein. (543 aa)
	Pias4.L	Uncharacterized protein. (544 aa)
	rac1	MGC114731 protein. (192 aa)
	nr3c1-2	XGR protein. (776 aa)
	sec61a1-2	Sec61a1 protein. (476 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	rac3	RAC1 protein. (192 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Daxx.L	Hdac3.S	A0A1L8F8G2	A0A1L8GVJ7	Daxx domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.515
Daxx.L	Pias4.L	A0A1L8F8G2	A0A1L8HW74	Daxx domain-containing protein.	Uncharacterized protein.	0.587
Daxx.L	Pias4.S	A0A1L8F8G2	A0A1L8HMW9	Daxx domain-containing protein.	Uncharacterized protein.	0.588
Daxx.L	Sumo1.L	A0A1L8F8G2	A0A1L8EWZ5	Daxx domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
Daxx.L	Sumo1.S	A0A1L8F8G2	A0A1L8EPQ0	Daxx domain-containing protein.	Ubiquitin-like domain-containing protein.	0.985
Daxx.L	nr3c1	A0A1L8F8G2	A0A1L8GV81	Daxx domain-containing protein.	Uncharacterized protein.	0.583
Daxx.L	nr3c1-2	A0A1L8F8G2	Q6DDL0	Daxx domain-containing protein.	XGR protein.	0.583
Daxx.L	sumo2	A0A1L8F8G2	A0A1L8EMU2	Daxx domain-containing protein.	Small ubiquitin-related modifier.	0.882
Gapdh.S	Sumo1.L	Q7ZY52	A0A1L8EWZ5	Glyceraldehyde-3-phosphate dehydrogenase.	Ubiquitin-like domain-containing protein.	0.411
Gapdh.S	Sumo1.S	Q7ZY52	A0A1L8EPQ0	Glyceraldehyde-3-phosphate dehydrogenase.	Ubiquitin-like domain-containing protein.	0.411
Gapdh.S	actl6a	Q7ZY52	Q7ZYI5	Glyceraldehyde-3-phosphate dehydrogenase.	Baf53a-pending-prov protein; Belongs to the actin family.	0.951
Gapdh.S	gapdh	Q7ZY52	Q8AY70	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Gapdh.S	sec61a1	Q7ZY52	A0A1L8GPS0	Glyceraldehyde-3-phosphate dehydrogenase.	Plug_translocon domain-containing protein.	0.484
Gapdh.S	sec61a1-2	Q7ZY52	Q7ZX87	Glyceraldehyde-3-phosphate dehydrogenase.	Sec61a1 protein.	0.484
Gapdh.S	sumo2	Q7ZY52	A0A1L8EMU2	Glyceraldehyde-3-phosphate dehydrogenase.	Small ubiquitin-related modifier.	0.451
Hdac3.S	Daxx.L	A0A1L8GVJ7	A0A1L8F8G2	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Daxx domain-containing protein.	0.515
Hdac3.S	Sumo1.L	A0A1L8GVJ7	A0A1L8EWZ5	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Ubiquitin-like domain-containing protein.	0.440
Hdac3.S	Sumo1.S	A0A1L8GVJ7	A0A1L8EPQ0	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Ubiquitin-like domain-containing protein.	0.440
Hdac3.S	kdm1a	A0A1L8GVJ7	A0A1L8HFM2	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.835
Hdac3.S	nr3c1	A0A1L8GVJ7	A0A1L8GV81	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein.	0.423