STRINGSTRING
pik3cb-2 pik3cb-2 Sox2.S Sox2.S Hnf4a.S Hnf4a.S Acvr1c.S Acvr1c.S stat3.1 stat3.1 Acvr1.L Acvr1.L neurod1 neurod1 Pou5f3.1 Pou5f3.1 pou5f3.2 pou5f3.2 nodal nodal Neurog3.S Neurog3.S Nodal.L Nodal.L Tnni3.L Tnni3.L A0A1L8FND1 A0A1L8FND1 Tgfbr1.S Tgfbr1.S gata6 gata6 Sox17a.S Sox17a.S sox17b.1 sox17b.1 mafa mafa wnt3a wnt3a ptf1a ptf1a sox17b.1-2 sox17b.1-2 mafa-2 mafa-2 mix1 mix1 tgfb2 tgfb2 tbxt tbxt pik3cb pik3cb gata4 gata4 tgfb2-2 tgfb2-2 Mixl1.L Mixl1.L nkx2-2-2 nkx2-2-2 Foxa2.L Foxa2.L Sst.2 Sst.2 ins ins pax6 pax6 pax6-2 pax6-2 Jun.L Jun.L A0A1L8GRI1 A0A1L8GRI1 Xnr2 Xnr2 pik3cg pik3cg nodal5 nodal5 Xnr5-6 Xnr5-6 A0A1L8H2D1 A0A1L8H2D1 A0A1L8H2D6 A0A1L8H2D6 Nodal3.2.L Nodal3.2.L nodal1 nodal1 A0A1L8H2G3 A0A1L8H2G3 Pdx1.S Pdx1.S pdx1 pdx1 Yap1.L Yap1.L Alb.S Alb.S Egf.L Egf.L LOC398065 LOC398065 nkx6-1 nkx6-1 nodal2 nodal2 bmp4 bmp4 ins-2 ins-2 tbx3-A tbx3-A LOC100189571 LOC100189571 XALK4 XALK4 LOC397803 LOC397803 sox9-a sox9-a nodal6 nodal6 Xnr5-3 Xnr5-3 ctnnb1 ctnnb1 neurod1-2 neurod1-2 gata4-2 gata4-2 tbxt-2 tbxt-2 myc myc sst sst Gapdh.S Gapdh.S gapdh gapdh bmp4-2 bmp4-2 nodal6-2 nodal6-2 nodal5.2 nodal5.2 tbx3 tbx3 c-Jun c-Jun
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
Sox2.SHMG box domain-containing protein. (194 aa)
Hnf4a.SUncharacterized protein. (466 aa)
Acvr1c.SReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
stat3.1Signal transducer and activator of transcription. (769 aa)
Acvr1.LReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (624 aa)
neurod1Neurogenic differentiation factor. (352 aa)
Pou5f3.1POU domain protein. (445 aa)
pou5f3.2POU domain protein. (449 aa)
nodalTGF_BETA_2 domain-containing protein. (402 aa)
Neurog3.SBHLH domain-containing protein. (304 aa)
Nodal.LTGF_BETA_2 domain-containing protein. (402 aa)
Tnni3.LUncharacterized protein. (238 aa)
A0A1L8FND1IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
Tgfbr1.SSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (454 aa)
gata6Uncharacterized protein. (502 aa)
Sox17a.SUncharacterized protein. (377 aa)
sox17b.1Uncharacterized protein. (373 aa)
mafaBZIP domain-containing protein. (288 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ptf1aBHLH domain-containing protein. (270 aa)
sox17b.1-2Uncharacterized protein. (373 aa)
mafa-2BZIP domain-containing protein. (297 aa)
mix1Homeobox domain-containing protein. (377 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
tbxtUncharacterized protein. (432 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
gata4Uncharacterized protein. (392 aa)
tgfb2-2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
Mixl1.LHomeobox domain-containing protein. (372 aa)
nkx2-2-2Homeobox domain-containing protein. (271 aa)
Foxa2.LFork-head domain-containing protein. (434 aa)
Sst.2Somatostatin domain-containing protein. (157 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
pax6Uncharacterized protein. (467 aa)
pax6-2Uncharacterized protein. (467 aa)
Jun.LBZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
A0A1L8GRI1TGF_BETA_2 domain-containing protein. (406 aa)
Xnr2TGF_BETA_2 domain-containing protein. (405 aa)
pik3cgUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
nodal5TGF_BETA_2 domain-containing protein. (384 aa)
Xnr5-6TGF_BETA_2 domain-containing protein. (386 aa)
A0A1L8H2D1TGF_BETA_2 domain-containing protein. (401 aa)
A0A1L8H2D6TGF_BETA_2 domain-containing protein. (348 aa)
Nodal3.2.LTGF_BETA_2 domain-containing protein. (401 aa)
nodal1TGF_BETA_2 domain-containing protein. (406 aa)
A0A1L8H2G3TGF_BETA_2 domain-containing protein. (401 aa)
Pdx1.SHomeobox domain-containing protein. (271 aa)
pdx1Homeobox domain-containing protein. (271 aa)
Yap1.LUncharacterized protein. (459 aa)
Alb.SUncharacterized protein. (607 aa)
Egf.LUncharacterized protein. (1031 aa)
LOC398065LOC398065 protein. (666 aa)
nkx6-1NK6 transcription factor related locus 1. (351 aa)
nodal2Xnr-2. (405 aa)
bmp4Bone morphogenetic protein 4. (401 aa)
ins-2Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
tbx3-ATranscription repression factor Tbx3. (716 aa)
LOC100189571Uncharacterized protein. (608 aa)
XALK4Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
LOC397803Cardiac troponin I. (244 aa)
sox9-aSex determining region Y-box 9. (477 aa)
nodal6Xnr6b protein. (379 aa)
Xnr5-3Xnr5-3. (386 aa)
ctnnb1Beta-catenin protein. (781 aa)
neurod1-2Neurogenic differentiation factor. (357 aa)
gata4-2MGC81427 protein. (394 aa)
tbxt-2MGC81453 protein. (432 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
sstPreprosomatostatin 1a. (115 aa)
Gapdh.SGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
bmp4-2Bone morphogenetic protein 4. (400 aa)
nodal6-2Xnr6. (378 aa)
nodal5.2Xnr5-10. (384 aa)
tbx3Transcription factor Tbx3. (711 aa)
c-JunC-Jun protein; Belongs to the bZIP family. (312 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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