17 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	impdh2-2	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (514 aa)
	impdh2	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (514 aa)
	impdh1	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (514 aa)
	gnat2	MGC84412 protein. (354 aa)
	gatd3a	Uncharacterized protein. (256 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	Ppat.L	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	ppat	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa)
	IMPDH	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (620 aa)
	Mcu.L	MCU domain-containing protein. (301 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Opsin	Rhodopsin. (403 aa)
	Rho.L	Rhodopsin. (459 aa)
	A0A1L8GHL0	Rhodopsin. (354 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GHL0	Alb.S	A0A1L8GHL0	A0A1L8HMG9	Rhodopsin.	Uncharacterized protein.	0.434
A0A1L8GHL0	LOC100189571	A0A1L8GHL0	B7ZRX0	Rhodopsin.	Uncharacterized protein.	0.434
A0A1L8GHL0	Opsin	A0A1L8GHL0	A0A1L8GPM0	Rhodopsin.	Rhodopsin.	0.900
A0A1L8GHL0	Rho.L	A0A1L8GHL0	A0A1L8GPJ9	Rhodopsin.	Rhodopsin.	0.901
A0A1L8GHL0	gnat2	A0A1L8GHL0	Q6DJF3	Rhodopsin.	MGC84412 protein.	0.948
Alb.S	A0A1L8GHL0	A0A1L8HMG9	A0A1L8GHL0	Uncharacterized protein.	Rhodopsin.	0.434
Alb.S	Opsin	A0A1L8HMG9	A0A1L8GPM0	Uncharacterized protein.	Rhodopsin.	0.434
Alb.S	Rho.L	A0A1L8HMG9	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.530
IMPDH	Ppat.L	A0A1L8GTM2	A0A1L8HTX2	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.762
IMPDH	gatd3a	A0A1L8GTM2	Q0P3R0	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Uncharacterized protein.	0.526
IMPDH	ppat	A0A1L8GTM2	A0A1L8HLC2	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.762
LOC100189571	A0A1L8GHL0	B7ZRX0	A0A1L8GHL0	Uncharacterized protein.	Rhodopsin.	0.434
LOC100189571	Opsin	B7ZRX0	A0A1L8GPM0	Uncharacterized protein.	Rhodopsin.	0.434
LOC100189571	Rho.L	B7ZRX0	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.548
Mcu.L	Ppat.L	A0A1L8FJV1	A0A1L8HTX2	MCU domain-containing protein.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.422
Mcu.L	gnat2	A0A1L8FJV1	Q6DJF3	MCU domain-containing protein.	MGC84412 protein.	0.482
Mcu.L	ppat	A0A1L8FJV1	A0A1L8HLC2	MCU domain-containing protein.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.422
Opsin	A0A1L8GHL0	A0A1L8GPM0	A0A1L8GHL0	Rhodopsin.	Rhodopsin.	0.900
Opsin	Alb.S	A0A1L8GPM0	A0A1L8HMG9	Rhodopsin.	Uncharacterized protein.	0.434
Opsin	LOC100189571	A0A1L8GPM0	B7ZRX0	Rhodopsin.	Uncharacterized protein.	0.434