17 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ccna2.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (415 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	trim28	Uncharacterized protein. (798 aa)
	Ddi2.L	Ubiquitin-like domain-containing protein. (393 aa)
	sprtn	Uncharacterized protein. (565 aa)
	Eif4g2.S	Uncharacterized protein. (908 aa)
	Nat1	Uncharacterized protein. (1006 aa)
	fancd2	Uncharacterized protein. (1445 aa)
	Ccna1.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
	Ccna1.L	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (421 aa)
	brca2	Tower domain-containing protein. (3177 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	ccna2	MGC130969 protein; Belongs to the cyclin family. (415 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca1.L	Ccna1.L	A0A1L8ETS4	A0A1L8HIV0	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.716
Brca1.L	Ccna1.S	A0A1L8ETS4	A0A1L8HAP9	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.716
Brca1.L	Ccna2.S	A0A1L8ETS4	A0A1L8HLX1	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.781
Brca1.L	Chek2.L	A0A1L8ETS4	A0A1L8I0A0	Uncharacterized protein.	Uncharacterized protein.	0.992
Brca1.L	Sumo1.L	A0A1L8ETS4	A0A1L8EWZ5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.712
Brca1.L	Sumo1.S	A0A1L8ETS4	A0A1L8EPQ0	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.712
Brca1.L	brca2	A0A1L8ETS4	A0A1L8HIX3	Uncharacterized protein.	Tower domain-containing protein.	0.999
Brca1.L	ccna2	A0A1L8ETS4	Q3KQ49	Uncharacterized protein.	MGC130969 protein; Belongs to the cyclin family.	0.781
Brca1.L	fancd2	A0A1L8ETS4	A0A1L8GP71	Uncharacterized protein.	Uncharacterized protein.	0.995
Brca1.L	pcna	A0A1L8ETS4	Q9I893	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.528
Brca1.L	sumo2	A0A1L8ETS4	A0A1L8EMU2	Uncharacterized protein.	Small ubiquitin-related modifier.	0.752
Ccna1.L	Brca1.L	A0A1L8HIV0	A0A1L8ETS4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.716
Ccna1.L	Ccna1.S	A0A1L8HIV0	A0A1L8HAP9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.415
Ccna1.L	Ccna2.S	A0A1L8HIV0	A0A1L8HLX1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.704
Ccna1.L	Chek2.L	A0A1L8HIV0	A0A1L8I0A0	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.771
Ccna1.L	brca2	A0A1L8HIV0	A0A1L8HIX3	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Tower domain-containing protein.	0.528
Ccna1.L	ccna2	A0A1L8HIV0	Q3KQ49	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	MGC130969 protein; Belongs to the cyclin family.	0.700
Ccna1.L	fancd2	A0A1L8HIV0	A0A1L8GP71	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.530
Ccna1.L	pcna	A0A1L8HIV0	Q9I893	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.582
Ccna1.S	Brca1.L	A0A1L8HAP9	A0A1L8ETS4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.716