(77 nodes) (2022) Viscoelasticity, Like Forces, Plays a Role in Mechanotransduction. network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pecam1	Uncharacterized protein. (684 aa)
	Fn1.S	Uncharacterized protein. (2480 aa)
	epn3-2	ENTH domain-containing protein. (601 aa)
	Itgav.L	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1080 aa)
	A0A1L8EYG2	ENTH domain-containing protein. (588 aa)
	Cfl2.S	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
	jag2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1223 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	A0A1L8F1S1	Uncharacterized protein. (2617 aa)
	l1cam	Uncharacterized protein. (1251 aa)
	arhgap35	Uncharacterized protein. (1476 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	arhgef11	Uncharacterized protein. (1606 aa)
	F11r.S	Uncharacterized protein. (289 aa)
	taz	Tafazzin family protein; Belongs to the taffazin family. (262 aa)
	notch1	Uncharacterized protein. (2521 aa)
	arhgap35-2	Uncharacterized protein. (1480 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	jag2-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1227 aa)
	cfl2	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
	fmn1	FH2 domain-containing protein. (1393 aa)
	arhgef11-2	Uncharacterized protein. (1593 aa)
	Epn2.S	ENTH domain-containing protein. (594 aa)
	Arhgef12.S	Uncharacterized protein. (1489 aa)
	arhgef12	Uncharacterized protein. (1464 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	Zeb1.S	Uncharacterized protein. (919 aa)
	snai2	Uncharacterized protein. (266 aa)
	jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1206 aa)
	Ect2.S	Uncharacterized protein. (987 aa)
	plod2	Fe2OG dioxygenase domain-containing protein. (740 aa)
	Jag1.L	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
	f11r	LOC398627 protein. (291 aa)
	src	Tyrosine-protein kinase. (532 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	fyn-2	Tyrosine-protein kinase. (537 aa)
	emd	Xemd1 protein. (180 aa)
	tnf-2	Tumor necrosis factor alpha. (225 aa)
	Flnb.L	Uncharacterized protein. (2603 aa)
	Tln2.S	Uncharacterized protein. (2612 aa)
	A0A1L8I385	Uncharacterized protein. (2303 aa)
	fga	Fibrinogen C-terminal domain-containing protein. (762 aa)
	Fga.S	Fibrinogen C-terminal domain-containing protein. (763 aa)
	kdr	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1326 aa)
	Mmp3.L	ZnMc domain-containing protein. (503 aa)
	Eln1.L	Uncharacterized protein. (904 aa)
	Serpine1.L	SERPIN domain-containing protein; Belongs to the serpin family. (403 aa)
	A0A1L8H034	Uncharacterized protein. (2543 aa)
	flnc	Uncharacterized protein. (2691 aa)
	net1-2	Uncharacterized protein. (583 aa)
	vwf	Uncharacterized protein. (2841 aa)
	net1	Uncharacterized protein. (584 aa)
	A0A1L8GTK8	Uncharacterized protein. (2691 aa)
	A0A1L8GTE5	Uncharacterized protein. (2543 aa)
	Rho.L	Rhodopsin. (459 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh5-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
	Cfl1.L	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
	piezo1	Piezo-type mechanosensitive ion channel component. (2474 aa)
	cdh5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	Cry2.S	Photolyase/cryptochrome alpha/beta domain-containing protein. (570 aa)
	cfl1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
	plod2-2	Fe2OG dioxygenase domain-containing protein. (761 aa)
	ect2	Uncharacterized protein. (986 aa)
	snai2-2	Zinc finger transcription factor slug beta. (266 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	dstn	MGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	rhoa	MGC64296 protein. (193 aa)
	rnd3-2	MGC83149 protein. (244 aa)
	rnd3	MGC83857 protein. (244 aa)
	pecam1-2	Platelet endothelial cell adhesion molecule. (727 aa)
	fyn	Tyrosine-protein kinase. (537 aa)
	rac1	MGC114731 protein. (192 aa)
	A0A1L8G7I3	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	epn3	ENTH domain-containing protein. (601 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F1S1	A0A1L8G7I3	A0A1L8F1S1	A0A1L8G7I3	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.571
A0A1L8F1S1	A0A1L8GTE5	A0A1L8F1S1	A0A1L8GTE5	Uncharacterized protein.	Uncharacterized protein.	0.860
A0A1L8F1S1	A0A1L8H034	A0A1L8F1S1	A0A1L8H034	Uncharacterized protein.	Uncharacterized protein.	0.859
A0A1L8F1S1	A0A1L8I385	A0A1L8F1S1	A0A1L8I385	Uncharacterized protein.	Uncharacterized protein.	0.858
A0A1L8F1S1	Cfl1.L	A0A1L8F1S1	A0A1L8GJZ1	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.575
A0A1L8F1S1	Cfl2.S	A0A1L8F1S1	A0A1L8EZQ8	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.575
A0A1L8F1S1	Itgav.L	A0A1L8F1S1	A0A1L8EX87	Uncharacterized protein.	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	0.738
A0A1L8F1S1	Tln2.S	A0A1L8F1S1	A0A310UCZ7	Uncharacterized protein.	Uncharacterized protein.	0.858
A0A1L8F1S1	actl6a	A0A1L8F1S1	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.980
A0A1L8F1S1	cfl1	A0A1L8F1S1	A0A1L8GCW3	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.575
A0A1L8F1S1	cfl2	A0A1L8F1S1	A0A1L8FAQ1	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.575
A0A1L8F1S1	dstn	A0A1L8F1S1	Q7ZXD4	Uncharacterized protein.	MGC53245 protein; Belongs to the actin-binding proteins ADF family.	0.571
A0A1L8F1S1	fmn1	A0A1L8F1S1	A0A1L8FAR9	Uncharacterized protein.	FH2 domain-containing protein.	0.441
A0A1L8F1S1	rac1	A0A1L8F1S1	Q58E25	Uncharacterized protein.	MGC114731 protein.	0.479
A0A1L8F1S1	rhoa	A0A1L8F1S1	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.678
A0A1L8G7I3	A0A1L8F1S1	A0A1L8G7I3	A0A1L8F1S1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.571
A0A1L8G7I3	A0A1L8GTE5	A0A1L8G7I3	A0A1L8GTE5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.510
A0A1L8G7I3	A0A1L8GTK8	A0A1L8G7I3	A0A1L8GTK8	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.571
A0A1L8G7I3	A0A1L8H034	A0A1L8G7I3	A0A1L8H034	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.509
A0A1L8G7I3	A0A1L8I385	A0A1L8G7I3	A0A1L8I385	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.509