45 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	atf2	Uncharacterized protein. (486 aa)
	msx1	Homeobox domain-containing protein. (275 aa)
	arhgef7-2	Uncharacterized protein. (802 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	arhgef7	Uncharacterized protein. (818 aa)
	nck2	Cytoplasmic protein. (381 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	Junb.L	BZIP domain-containing protein. (306 aa)
	wif1	Uncharacterized protein. (374 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	Rho.L	Rhodopsin. (459 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	ryk	Uncharacterized protein. (596 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	prdm1-2	Uncharacterized protein. (780 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	prdm1	Uncharacterized protein. (780 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)
	gata6	Uncharacterized protein. (502 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	dicer1	Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1891 aa)
	Dicer1.S	Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1768 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	rhoa	MGC64296 protein. (193 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	fos-2	MGC80305 protein. (368 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	src	Tyrosine-protein kinase. (532 aa)
	edn1	LOC100158354 protein. (221 aa)
	nck1	Cytoplasmic protein. (377 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	vegfa	Vascular endothelial growth factor 196; Belongs to the PDGF/VEGF growth factor family. (194 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	fos	BZIP domain-containing protein. (369 aa)
	msx1-2	LOC100125666 protein. (273 aa)
	jund	BZIP domain-containing protein. (300 aa)
	Jund.S	BZIP domain-containing protein. (300 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8H5Q6	Axin1.S	A0A1L8H5Q6	A0A1L8ER48	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.999
A0A1L8H5Q6	Jun.L	A0A1L8H5Q6	A0A1L8GLZ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	BZIP domain-containing protein; Belongs to the bZIP family.	0.598
A0A1L8H5Q6	Lrp5.L	A0A1L8H5Q6	A0A1L8GJX4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.896
A0A1L8H5Q6	Myc.S	A0A1L8H5Q6	A0A1L8FTW7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Myc_N domain-containing protein.	0.626
A0A1L8H5Q6	actl6a	A0A1L8H5Q6	Q7ZYI5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Baf53a-pending-prov protein; Belongs to the actin family.	0.428
A0A1L8H5Q6	c-Jun	A0A1L8H5Q6	Q9PVZ1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	C-Jun protein; Belongs to the bZIP family.	0.600
A0A1L8H5Q6	ctnnb1	A0A1L8H5Q6	Q63ZT4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Beta-catenin protein.	0.999
A0A1L8H5Q6	dkk1	A0A1L8H5Q6	A0A1L8FIS6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf_N domain-containing protein.	0.606
A0A1L8H5Q6	dkk1-2	A0A1L8H5Q6	O57464	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf homolog 1.	0.606
A0A1L8H5Q6	dkk2	A0A1L8H5Q6	A0A1L8HM80	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf_N domain-containing protein.	0.467
A0A1L8H5Q6	dkk2-2	A0A1L8H5Q6	Q9DDA4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf homolog 2.	0.467
A0A1L8H5Q6	myc	A0A1L8H5Q6	Q6NRN4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.626
A0A1L8H5Q6	nck1	A0A1L8H5Q6	P79956	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cytoplasmic protein.	0.564
A0A1L8H5Q6	nck1-2	A0A1L8H5Q6	Q32NQ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cytoplasmic protein.	0.564
A0A1L8H5Q6	nck2	A0A1L8H5Q6	A0A1L8H8L9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cytoplasmic protein.	0.607
A0A1L8H5Q6	nck2-2	A0A1L8H5Q6	A0A1L8HGP4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cytoplasmic protein.	0.607
A0A1L8H5Q6	rhoa	A0A1L8H5Q6	Q7SZA9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	MGC64296 protein.	0.481
A0A1L8H5Q6	ryk	A0A1L8H5Q6	A0A1L8GB75	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.468
A0A1L8H5Q6	wif1	A0A1L8H5Q6	A0A1L8GYI2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.467
A0A1L8H5Q6	wif1-2	A0A1L8H5Q6	B7ZPZ2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Wnt inhibitory factor-1.	0.467