15 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	atrip	Uncharacterized protein. (801 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	lgals4.2	Galectin. (319 aa)
	mdc1	Uncharacterized protein. (2103 aa)
	Lgals4.L	Galectin. (319 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	rbbp8	Uncharacterized protein. (846 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Rbbp8.L	Uncharacterized protein. (856 aa)
	A0A1L8G058	Uncharacterized protein. (2287 aa)
	Rad26	Uncharacterized protein. (798 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca1.L	Hus1	A0A1L8ETS4	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.885
Brca1.L	Rad26	A0A1L8ETS4	A0A1L8GP12	Uncharacterized protein.	Uncharacterized protein.	0.959
Brca1.L	Rbbp8.L	A0A1L8ETS4	A0A1L8FYP2	Uncharacterized protein.	Uncharacterized protein.	0.999
Brca1.L	atrip	A0A1L8ETS4	A0A1L8GH95	Uncharacterized protein.	Uncharacterized protein.	0.959
Brca1.L	chek1	A0A1L8ETS4	A0A1L8FFS1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.980
Brca1.L	chek1-2	A0A1L8ETS4	A0A1L8FL95	Uncharacterized protein.	Protein kinase domain-containing protein.	0.980
Brca1.L	mdc1	A0A1L8ETS4	A0A1L8F8K7	Uncharacterized protein.	Uncharacterized protein.	0.975
Brca1.L	myc	A0A1L8ETS4	Q6NRN4	Uncharacterized protein.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.749
Brca1.L	rad9a	A0A1L8ETS4	Q7ZZU5	Uncharacterized protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.905
Brca1.L	rbbp8	A0A1L8ETS4	A0A1L8FSU5	Uncharacterized protein.	Uncharacterized protein.	0.999
Brca1.L	topbp1	A0A1L8ETS4	A0A1L8FWJ6	Uncharacterized protein.	Uncharacterized protein.	0.999
Hus1	Brca1.L	Q8JHD8	A0A1L8ETS4	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.885
Hus1	Rad26	Q8JHD8	A0A1L8GP12	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.982
Hus1	Rbbp8.L	Q8JHD8	A0A1L8FYP2	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.842
Hus1	atrip	Q8JHD8	A0A1L8GH95	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.981
Hus1	chek1	Q8JHD8	A0A1L8FFS1	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.981
Hus1	chek1-2	Q8JHD8	A0A1L8FL95	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein.	0.985
Hus1	mdc1	Q8JHD8	A0A1L8F8K7	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.747
Hus1	rad9a	Q8JHD8	Q7ZZU5	Checkpoint protein; Belongs to the HUS1 family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.999
Hus1	rbbp8	Q8JHD8	A0A1L8FSU5	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.842