39 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	tgfb2-2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	Slc17a7.L	MFS domain-containing protein. (576 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	dnmbp-2	Uncharacterized protein. (1552 aa)
	dnmbp	Uncharacterized protein. (1548 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	Was.L	Uncharacterized protein. (471 aa)
	Was.S	Uncharacterized protein. (472 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	bmp7.1	TGF_BETA_2 domain-containing protein. (424 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	bmp7.1-2	Osteogenic protein-1 homolog. (424 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	rhoa	MGC64296 protein. (193 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	bdnf-2	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	rac1	MGC114731 protein. (192 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	LOC398022	Tyrosine-protein kinase receptor. (1363 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	map1b-2	Uncharacterized protein. (2255 aa)
	Ntrk2.S	Tyrosine-protein kinase receptor. (821 aa)
	A0A1L8HTQ2	Uncharacterized protein. (1521 aa)
	map1b	Uncharacterized protein. (2247 aa)
	ntrk2	Tyrosine-protein kinase receptor. (807 aa)
	Slit2.S	Uncharacterized protein. (1530 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	igf1r	Tyrosine-protein kinase receptor. (1358 aa)
	Bmp7.2.L	TGF_BETA_2 domain-containing protein. (438 aa)
	reln	Uncharacterized protein. (3461 aa)
	rap1b	Uncharacterized protein. (184 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYQ3	actl6a	A0A1L8EYQ3	Q7ZYI5	LLGL domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.439
A0A1L8FND1	LOC398022	A0A1L8FND1	B7ZSL0	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.994
A0A1L8FND1	Ntrk2.S	A0A1L8FND1	A0A1L8HZ01	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.818
A0A1L8FND1	actl6a	A0A1L8FND1	Q7ZYI5	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Baf53a-pending-prov protein; Belongs to the actin family.	0.733
A0A1L8FND1	bdnf	A0A1L8FND1	A0A1L8GDT3	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.664
A0A1L8FND1	bdnf-2	A0A1L8FND1	Q63ZM5	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.664
A0A1L8FND1	cdh2	A0A1L8FND1	A0A1L8FSZ9	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.447
A0A1L8FND1	igf1r	A0A1L8FND1	A0A1L8H104	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.994
A0A1L8FND1	ins	A0A1L8FND1	A0A1L8GD41	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.907
A0A1L8FND1	ins-2	A0A1L8FND1	B7ZQP1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.905
A0A1L8FND1	ntrk2	A0A1L8FND1	A0A1L8HPC8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.818
A0A1L8FND1	rhoa	A0A1L8FND1	Q7SZA9	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MGC64296 protein.	0.476
A0A1L8FND1	tgfb1	A0A1L8FND1	A0A1L8F3Y7	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.683
A0A1L8FND1	tgfb1-2	A0A1L8FND1	A0A1L8F936	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.683
A0A1L8HTQ2	bdnf	A0A1L8HTQ2	A0A1L8GDT3	Uncharacterized protein.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.634
A0A1L8HTQ2	bdnf-2	A0A1L8HTQ2	Q63ZM5	Uncharacterized protein.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.634
A0A1L8HTQ2	rhoa	A0A1L8HTQ2	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.537
Bmp7.2.L	actl6a	A0A1L8H0A1	Q7ZYI5	TGF_BETA_2 domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.430
LOC398022	A0A1L8FND1	B7ZSL0	A0A1L8FND1	Tyrosine-protein kinase receptor.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.994
LOC398022	bdnf	B7ZSL0	A0A1L8GDT3	Tyrosine-protein kinase receptor.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.767