44 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8EN80	Uncharacterized protein. (202 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	rcvrn.2-2	MGC84424 protein. (192 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	fos-2	MGC80305 protein. (368 aa)
	rcvrn.2	MGC84117 protein. (192 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	neurog2-2	Neurogenin-related 1b. (215 aa)
	neurog2	Neurogenin-related 1a. (214 aa)
	atoh7	Atonal homolog 5a. (138 aa)
	fos	BZIP domain-containing protein. (369 aa)
	Ikzf1.S	C2H2-type domain-containing protein. (273 aa)
	gas1-2	Uncharacterized protein. (284 aa)
	gas1	Uncharacterized protein. (299 aa)
	Yap1.L	Uncharacterized protein. (459 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	olig2	BHLH domain-containing protein. (360 aa)
	Ascl1.L	BHLH domain-containing protein. (242 aa)
	Cdkn1b.S	Uncharacterized protein. (152 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	sox11	Transcription factor SOX. (382 aa)
	prox1-2	Prospero domain-containing protein. (740 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	Sox11.S	Transcription factor SOX. (373 aa)
	prox1	Prospero domain-containing protein. (739 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	ikzf1	Uncharacterized protein. (567 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)
	fgfr2-2	Fibroblast growth factor receptor. (832 aa)
	fgfr2	Fibroblast growth factor receptor. (830 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	arl13a	Uncharacterized protein. (421 aa)
	notch1	Uncharacterized protein. (2521 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	Vsx2.L	Uncharacterized protein. (344 aa)
	A0A1L8EUU9	Uncharacterized protein. (202 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EN80	Vsx2.L	A0A1L8EN80	A0A1L8F0U1	Uncharacterized protein.	Uncharacterized protein.	0.834
A0A1L8EN80	atoh7	A0A1L8EN80	B7ZQX7	Uncharacterized protein.	Atonal homolog 5a.	0.455
A0A1L8EUU9	Vsx2.L	A0A1L8EUU9	A0A1L8F0U1	Uncharacterized protein.	Uncharacterized protein.	0.834
A0A1L8EUU9	atoh7	A0A1L8EUU9	B7ZQX7	Uncharacterized protein.	Atonal homolog 5a.	0.455
Ascl1.L	Myc.S	A0A1L8GY38	A0A1L8FTW7	BHLH domain-containing protein.	Myc_N domain-containing protein.	0.497
Ascl1.L	Notch1.S	A0A1L8GY38	A0A1L8F124	BHLH domain-containing protein.	Uncharacterized protein.	0.794
Ascl1.L	Shh.L	A0A1L8GY38	A0A1L8FV87	BHLH domain-containing protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.700
Ascl1.L	Sox11.S	A0A1L8GY38	A0A1L8G567	BHLH domain-containing protein.	Transcription factor SOX.	0.502
Ascl1.L	Vsx2.L	A0A1L8GY38	A0A1L8F0U1	BHLH domain-containing protein.	Uncharacterized protein.	0.680
Ascl1.L	ctnnb1	A0A1L8GY38	Q63ZT4	BHLH domain-containing protein.	Beta-catenin protein.	0.502
Ascl1.L	myc	A0A1L8GY38	Q6NRN4	BHLH domain-containing protein.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.546
Ascl1.L	neurog2	A0A1L8GY38	P70050	BHLH domain-containing protein.	Neurogenin-related 1a.	0.486
Ascl1.L	neurog2-2	A0A1L8GY38	P70051	BHLH domain-containing protein.	Neurogenin-related 1b.	0.479
Ascl1.L	notch1	A0A1L8GY38	A0A1L8F627	BHLH domain-containing protein.	Uncharacterized protein.	0.790
Ascl1.L	olig2	A0A1L8GY38	A0A1L8H592	BHLH domain-containing protein.	BHLH domain-containing protein.	0.820
Ascl1.L	prox1	A0A1L8GY38	A0A1L8G1A4	BHLH domain-containing protein.	Prospero domain-containing protein.	0.479
Ascl1.L	prox1-2	A0A1L8GY38	A0A1L8G6G5	BHLH domain-containing protein.	Prospero domain-containing protein.	0.479
Ascl1.L	sox11	A0A1L8GY38	A0A1L8GBJ0	BHLH domain-containing protein.	Transcription factor SOX.	0.464
Cdkn1b.S	Jun.L	A0A1L8GQW1	A0A1L8GLZ4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.456
Cdkn1b.S	Myc.S	A0A1L8GQW1	A0A1L8FTW7	Uncharacterized protein.	Myc_N domain-containing protein.	0.589