38 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	erbb2	Receptor protein-tyrosine kinase. (1299 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	A0A1L8F1S1	Uncharacterized protein. (2617 aa)
	efna1	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (216 aa)
	A0A1L8F599	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (97 aa)
	notch1	Uncharacterized protein. (2521 aa)
	efna3	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (217 aa)
	Epha2.L	Uncharacterized protein. (948 aa)
	Vim.S	IF rod domain-containing protein; Belongs to the intermediate filament family. (463 aa)
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	plec	Uncharacterized protein. (4578 aa)
	Vim.L	IF rod domain-containing protein; Belongs to the intermediate filament family. (458 aa)
	A0A1L8G0G1	Uncharacterized protein. (4578 aa)
	rock2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1399 aa)
	Rock2.L	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	A0A1L8GTK8	Uncharacterized protein. (2691 aa)
	s1pr2	G_PROTEIN_RECEP_F1_2 domain-containing protein. (349 aa)
	flnc	Uncharacterized protein. (2691 aa)
	s1pr2-2	G_PROTEIN_RECEP_F1_2 domain-containing protein. (349 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	Efna2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (198 aa)
	Efna5.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	Efna2.L	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (198 aa)
	pxn	Uncharacterized protein; Belongs to the paxillin family. (542 aa)
	Efna5.L	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	Flnb.L	Uncharacterized protein. (2603 aa)
	src	Tyrosine-protein kinase. (532 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	cav1a	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	pxn-2	LOC397826 protein; Belongs to the paxillin family. (539 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F1S1	actl6a	A0A1L8F1S1	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.980
A0A1L8F1S1	cav1a	A0A1L8F1S1	Q6IRP8	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.411
A0A1L8F1S1	pxn	A0A1L8F1S1	A0A1L8I058	Uncharacterized protein.	Uncharacterized protein; Belongs to the paxillin family.	0.546
A0A1L8F1S1	pxn-2	A0A1L8F1S1	Q9I957	Uncharacterized protein.	LOC397826 protein; Belongs to the paxillin family.	0.546
A0A1L8F599	Epha2.L	A0A1L8F599	A0A1L8FPA0	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Uncharacterized protein.	0.909
A0A1L8F599	erbb2	A0A1L8F599	A0A1L8ES20	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Receptor protein-tyrosine kinase.	0.706
A0A1L8F599	src	A0A1L8F599	Q2TAR1	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Tyrosine-protein kinase.	0.453
A0A1L8G0G1	actl6a	A0A1L8G0G1	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.852
A0A1L8G0G1	pxn	A0A1L8G0G1	A0A1L8I058	Uncharacterized protein.	Uncharacterized protein; Belongs to the paxillin family.	0.564
A0A1L8G0G1	pxn-2	A0A1L8G0G1	Q9I957	Uncharacterized protein.	LOC397826 protein; Belongs to the paxillin family.	0.564
A0A1L8G0G1	src	A0A1L8G0G1	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.476
A0A1L8GTK8	actl6a	A0A1L8GTK8	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.982
A0A1L8GTK8	pxn	A0A1L8GTK8	A0A1L8I058	Uncharacterized protein.	Uncharacterized protein; Belongs to the paxillin family.	0.539
A0A1L8GTK8	pxn-2	A0A1L8GTK8	Q9I957	Uncharacterized protein.	LOC397826 protein; Belongs to the paxillin family.	0.539
Bcl2.S	Casp3.L	A0A1L8FSA4	A0A1L8HU08	BH4_2 domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.957
Bcl2.S	Cdh3.S	A0A1L8FSA4	A0A1L8GET9	BH4_2 domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.539
Bcl2.S	Notch1.S	A0A1L8FSA4	A0A1L8F124	BH4_2 domain-containing protein.	Uncharacterized protein.	0.519
Bcl2.S	Tp53.L	A0A1L8FSA4	A0A1L8H4M6	BH4_2 domain-containing protein.	P53 domain-containing protein.	0.981
Bcl2.S	actl6a	A0A1L8FSA4	Q7ZYI5	BH4_2 domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.542
Bcl2.S	casp3.2	A0A1L8FSA4	A0A1L8HLJ6	BH4_2 domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.957