20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	Socs3.S	Uncharacterized protein. (250 aa)
	grb2	Uncharacterized protein. (229 aa)
	stat3.1	Signal transducer and activator of transcription. (769 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	Pou5f3.1	POU domain protein. (445 aa)
	pou5f3.2	POU domain protein. (449 aa)
	A0A1L8FW11	Uncharacterized protein. (139 aa)
	map2k1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	rexo1	Exonuclease domain-containing protein. (1135 aa)
	A0A1L8HPW4	Uncharacterized protein. (216 aa)
	rexo1-2	Exonuclease domain-containing protein. (1136 aa)
	lif	Uncharacterized protein. (216 aa)
	src	Tyrosine-protein kinase. (532 aa)
	gab1	MGC81548 protein. (691 aa)
	zap70	Tyrosine-protein kinase. (617 aa)
	ptpn2	Tyrosine-protein phosphatase non-receptor type. (468 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	socs3	MGC81248 protein. (199 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FW11	A0A1L8HPW4	A0A1L8FW11	A0A1L8HPW4	Uncharacterized protein.	Uncharacterized protein.	0.678
A0A1L8FW11	Ptpn11.S	A0A1L8FW11	Q92124	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.530
A0A1L8FW11	Socs3.S	A0A1L8FW11	A0A1L8EM41	Uncharacterized protein.	Uncharacterized protein.	0.718
A0A1L8FW11	fgf2	A0A1L8FW11	A0A1L8HLX5	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.447
A0A1L8FW11	lif	A0A1L8FW11	A0A1L8HZU9	Uncharacterized protein.	Uncharacterized protein.	0.678
A0A1L8FW11	map2k1	A0A1L8FW11	A0A1L8GSC6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.446
A0A1L8FW11	ptpn11b	A0A1L8FW11	Q6GP31	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.530
A0A1L8FW11	socs3	A0A1L8FW11	Q6NU49	Uncharacterized protein.	MGC81248 protein.	0.718
A0A1L8FW11	src	A0A1L8FW11	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.456
A0A1L8FW11	stat3.1	A0A1L8FW11	A0A1L8ERT1	Uncharacterized protein.	Signal transducer and activator of transcription.	0.883
A0A1L8HPW4	A0A1L8FW11	A0A1L8HPW4	A0A1L8FW11	Uncharacterized protein.	Uncharacterized protein.	0.678
A0A1L8HPW4	Pou5f3.1	A0A1L8HPW4	A0A1L8F5T5	Uncharacterized protein.	POU domain protein.	0.779
A0A1L8HPW4	Socs3.S	A0A1L8HPW4	A0A1L8EM41	Uncharacterized protein.	Uncharacterized protein.	0.406
A0A1L8HPW4	fgf2	A0A1L8HPW4	A0A1L8HLX5	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.600
A0A1L8HPW4	lif	A0A1L8HPW4	A0A1L8HZU9	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8HPW4	pou5f3.2	A0A1L8HPW4	A0A1L8F5T8	Uncharacterized protein.	POU domain protein.	0.777
A0A1L8HPW4	socs3	A0A1L8HPW4	Q6NU49	Uncharacterized protein.	MGC81248 protein.	0.406
A0A1L8HPW4	stat3.1	A0A1L8HPW4	A0A1L8ERT1	Uncharacterized protein.	Signal transducer and activator of transcription.	0.743
Pou5f3.1	A0A1L8HPW4	A0A1L8F5T5	A0A1L8HPW4	POU domain protein.	Uncharacterized protein.	0.779
Pou5f3.1	fgf2	A0A1L8F5T5	A0A1L8HLX5	POU domain protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.568