STRINGSTRING
usp19 usp19 pcna pcna neurl1-2 neurl1-2 ccnd1 ccnd1 cdc20-2 cdc20-2 hspa1l hspa1l prpf19 prpf19 psmd14 psmd14 rnf167 rnf167 snca snca eloc eloc ube2a ube2a bnip3-2 bnip3-2 myc myc peli2 peli2 ube2d1 ube2d1 ube2g2 ube2g2 fbxl14 fbxl14 usp5-2 usp5-2 arih2 arih2 psmd7-2 psmd7-2 ube2e2 ube2e2 uchl3-2 uchl3-2 ube2c-2 ube2c-2 otub1 otub1 dtx1-2 dtx1-2 rnf128-2 rnf128-2 fbxl17 fbxl17 rnf20 rnf20 atg12 atg12 anapc13.2 anapc13.2 usp3-2 usp3-2 usp5 usp5 A0A310TYC6 A0A310TYC6 pik3c3 pik3c3 Fbxw8.L Fbxw8.L atg10 atg10 pja2 pja2 znrf3 znrf3 fbxo21 fbxo21 dtx1 dtx1 A0A1L8HY60 A0A1L8HY60 herc6 herc6 rnf150-2 rnf150-2 uchl1 uchl1 fbxo41 fbxo41 Vcp.S Vcp.S Nedd4l.S Nedd4l.S chd1 chd1 Pja2.S Pja2.S Znrf3.S Znrf3.S A0A1L8HPJ8 A0A1L8HPJ8 rnf31 rnf31 rnf126 rnf126 Herc6.S Herc6.S A0A1L8HMD5 A0A1L8HMD5 h2afz h2afz rnf150 rnf150 Uchl1.L Uchl1.L Ubox5.S Ubox5.S ufm1-2 ufm1-2 dtx3 dtx3 rnf19b-2 rnf19b-2 usp9x-2 usp9x-2 ufm1 ufm1 march9 march9 uchl3 uchl3 rnf19b rnf19b ube2t ube2t usp9x usp9x Fundc1.S Fundc1.S Prpf8.S Prpf8.S rnf43 rnf43 Tp53.L Tp53.L Stambp.L Stambp.L dnaaf4 dnaaf4 arih1-2 arih1-2 fbxl13 fbxl13 Usp44.L Usp44.L ube2n ube2n rnf44-2 rnf44-2 neurl1b-2 neurl1b-2 aff4 aff4 rnf14.4 rnf14.4 rnf14.1 rnf14.1 skp1-2 skp1-2 neurl1b neurl1b rnf44 rnf44 usp44 usp44 Ube2n.S Ube2n.S arih1 arih1 usp3 usp3 A0A1L8GS29 A0A1L8GS29 ube2d4 ube2d4 Stambp.S Stambp.S skp1 skp1 mkrn1 mkrn1 Usp4.L Usp4.L Josd1.L Josd1.L Rnf2.L Rnf2.L cdc20 cdc20 mysm1 mysm1 ube2u ube2u fbxl8 fbxl8 Otub1.L Otub1.L usp4 usp4 josd1 josd1 usp1 usp1 psmd7 psmd7 Nae1.S Nae1.S ddb1 ddb1 fbxo16 fbxo16 rnf144a-2 rnf144a-2 fbxo45-2 fbxo45-2 usp13-2 usp13-2 hes1-2 hes1-2 Rnf217.L Rnf217.L trim67-2 trim67-2 Fancl.L Fancl.L A0A1L8G719 A0A1L8G719 traf5 traf5 fbxo45 fbxo45 rnf144a rnf144a fbxo36 fbxo36 hes1 hes1 usp13 usp13 Ube3d.S Ube3d.S Tnfaip3.S Tnfaip3.S trim67 trim67 anapc1 anapc1 Peli2.S Peli2.S eif3h eif3h rnf19a-2 rnf19a-2 wwp1 wwp1 rnf144b-2 rnf144b-2 ube2ql1-2 ube2ql1-2 otud1 otud1 Fam188b.L Fam188b.L Myc.S Myc.S EIF3H EIF3H rnf19a rnf19a ube2v2 ube2v2 fbxo15 fbxo15 rnf144b rnf144b otulin otulin ube2ql1 ube2ql1 uba5 uba5 ankib1 ankib1 ube2s-2 ube2s-2 trim28-2 trim28-2 ube4a ube4a usp2-2 usp2-2 cbl cbl ube4b ube4b anapc16-2 anapc16-2 bnip3 bnip3 stambpl1 stambpl1 ube2s ube2s trim28 trim28 Ube4a.S Ube4a.S anapc16 anapc16 neurl1 neurl1 gabarapl1 gabarapl1 A0A1L8FAC5 A0A1L8FAC5 Atxn3.L Atxn3.L ubr7 ubr7 sae1 sae1 ring1 ring1 trim32 trim32 cdc26 cdc26 anapc2 anapc2 EIF3F EIF3F Ring1.S Ring1.S rnf128 rnf128 URM1 URM1 atxn3 atxn3 Uba1.S Uba1.S Elob.L Elob.L stub1-2 stub1-2 Ccnf.L Ccnf.L usp7-2 usp7-2 rnf216 rnf216 Sumo1.L Sumo1.L fbxw10 fbxw10 sumo2-2 sumo2-2 ube2c ube2c Ube2v1.L Ube2v1.L ube2z-2 ube2z-2 dnajc7-2 dnajc7-2 stub1 stub1 ube2i ube2i usp7 usp7 Sumo1.S Sumo1.S wdsub1 wdsub1 sumo2 sumo2 ube2z ube2z dnajc7 dnajc7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
usp19Uncharacterized protein. (1432 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
neurl1-2Neuralized. (555 aa)
ccnd1Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
cdc20-2Cdc20 protein. (506 aa)
hspa1lHsc70 protein; Belongs to the heat shock protein 70 family. (650 aa)
prpf19Nmp200-prov protein. (504 aa)
psmd14Psmd14-prov protein. (310 aa)
rnf167MGC69137 protein. (336 aa)
sncaAlpha-synuclein; Belongs to the synuclein family. (141 aa)
elocTceb1-prov protein. (112 aa)
ube2aMGC68540 protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
bnip3-2MGC68574 protein. (202 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
peli2MGC80329 protein. (419 aa)
ube2d1Ube2d2-prov protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ube2g2MGC82328 protein; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
fbxl14Fbl13 protein. (400 aa)
usp5-2Ubiquitin carboxyl-terminal hydrolase. (855 aa)
arih2RBR-type E3 ubiquitin transferase. (492 aa)
psmd7-2MGC84052 protein. (320 aa)
ube2e2LOC494805 protein; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
uchl3-2Ubiquitin carboxyl-terminal hydrolase. (230 aa)
ube2c-2LOC496302 protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
otub1Ubiquitin thioesterase. (269 aa)
dtx1-2XDTX1 protein. (623 aa)
rnf128-2Goliath-related E3 ubiquitin ligase 1. (404 aa)
fbxl17F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteaseome (By similarity). The ability of the SCF(FBXL17) complex to eliminate co [...] (673 aa)
rnf20E3 ubiquitin protein ligase. (965 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (132 aa)
anapc13.2LOC100037155 protein. (74 aa)
usp3-2Ubiquitin carboxyl-terminal hydrolase. (522 aa)
usp5Ubiquitin carboxyl-terminal hydrolase. (832 aa)
A0A310TYC6Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (96 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
Fbxw8.LUncharacterized protein. (606 aa)
atg10Autophagy_act_C domain-containing protein. (214 aa)
pja2RING-type domain-containing protein. (646 aa)
znrf3RING-type domain-containing protein. (854 aa)
fbxo21YccV-like domain-containing protein. (614 aa)
dtx1Uncharacterized protein. (623 aa)
A0A1L8HY60Uncharacterized protein. (222 aa)
herc6HECT domain-containing protein. (1027 aa)
rnf150-2RING-type domain-containing protein. (427 aa)
uchl1Ubiquitin carboxyl-terminal hydrolase. (252 aa)
fbxo41F-box domain-containing protein. (802 aa)
Vcp.SUncharacterized protein; Belongs to the AAA ATPase family. (805 aa)
Nedd4l.SUncharacterized protein. (979 aa)
chd1Uncharacterized protein. (1793 aa)
Pja2.SRING-type domain-containing protein. (678 aa)
Znrf3.SRING-type domain-containing protein. (848 aa)
A0A1L8HPJ8Ubiquitin-like domain-containing protein. (125 aa)
rnf31Uncharacterized protein. (1057 aa)
rnf126RING-type domain-containing protein. (312 aa)
Herc6.SHECT domain-containing protein. (935 aa)
A0A1L8HMD5Alpha-synuclein; Belongs to the synuclein family. (212 aa)
h2afzHistone H2A; Belongs to the histone H2A family. (128 aa)
rnf150RING-type domain-containing protein. (427 aa)
Uchl1.LUbiquitin carboxyl-terminal hydrolase. (223 aa)
Ubox5.SU-box domain-containing protein. (540 aa)
ufm1-2Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (85 aa)
dtx3RING-type domain-containing protein. (353 aa)
rnf19b-2RBR-type E3 ubiquitin transferase. (685 aa)
usp9x-2USP domain-containing protein; Belongs to the peptidase C19 family. (2545 aa)
ufm1Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (85 aa)
march9RING-CH-type domain-containing protein. (333 aa)
uchl3Ubiquitin carboxyl-terminal hydrolase. (230 aa)
rnf19bRBR-type E3 ubiquitin transferase. (713 aa)
ube2tUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (192 aa)
usp9xUSP domain-containing protein; Belongs to the peptidase C19 family. (2545 aa)
Fundc1.SUncharacterized protein. (177 aa)
Prpf8.SMPN domain-containing protein. (2335 aa)
rnf43RING-type domain-containing protein. (664 aa)
Tp53.LP53 domain-containing protein. (137 aa)
Stambp.LMPN domain-containing protein. (416 aa)
dnaaf4Uncharacterized protein. (411 aa)
arih1-2RBR-type E3 ubiquitin transferase. (529 aa)
fbxl13F-box domain-containing protein. (808 aa)
Usp44.LUbiquitin carboxyl-terminal hydrolase. (704 aa)
ube2nUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
rnf44-2RING-type domain-containing protein. (429 aa)
neurl1b-2Uncharacterized protein. (552 aa)
aff4Uncharacterized protein. (1144 aa)
rnf14.4RBR-type E3 ubiquitin transferase. (472 aa)
rnf14.1RBR-type E3 ubiquitin transferase. (469 aa)
skp1-2Uncharacterized protein; Belongs to the SKP1 family. (221 aa)
neurl1bUncharacterized protein. (552 aa)
rnf44RING-type domain-containing protein. (430 aa)
usp44Ubiquitin carboxyl-terminal hydrolase. (704 aa)
Ube2n.SUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
arih1RBR-type E3 ubiquitin transferase. (572 aa)
usp3Ubiquitin carboxyl-terminal hydrolase. (519 aa)
A0A1L8GS29Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
ube2d4UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
Stambp.SMPN domain-containing protein. (500 aa)
skp1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
mkrn1Uncharacterized protein. (449 aa)
Usp4.LUbiquitin carboxyl-terminal hydrolase. (977 aa)
Josd1.LJosephin domain-containing protein. (201 aa)
Rnf2.LRING-type domain-containing protein. (354 aa)
cdc20WD_REPEATS_REGION domain-containing protein. (512 aa)
mysm1Uncharacterized protein. (828 aa)
ube2uUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (319 aa)
fbxl8F-box domain-containing protein. (382 aa)
Otub1.LUbiquitin thioesterase. (268 aa)
usp4Ubiquitin carboxyl-terminal hydrolase. (977 aa)
josd1Josephin domain-containing protein. (201 aa)
usp1Ubiquitin carboxyl-terminal hydrolase. (766 aa)
psmd7MPN domain-containing protein. (320 aa)
Nae1.SNEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (533 aa)
ddb1CPSF_A domain-containing protein. (1140 aa)
fbxo16F-box domain-containing protein. (370 aa)
rnf144a-2RBR-type E3 ubiquitin transferase. (292 aa)
fbxo45-2Uncharacterized protein. (281 aa)
usp13-2Ubiquitin carboxyl-terminal hydrolase. (844 aa)
hes1-2Uncharacterized protein. (267 aa)
Rnf217.LRBR-type E3 ubiquitin transferase. (91 aa)
trim67-2Uncharacterized protein. (522 aa)
Fancl.LRING-type domain-containing protein. (361 aa)
A0A1L8G719Uncharacterized protein. (418 aa)
traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (555 aa)
fbxo45Uncharacterized protein. (280 aa)
rnf144aRBR-type E3 ubiquitin transferase. (292 aa)
fbxo36F-box domain-containing protein. (220 aa)
hes1Uncharacterized protein. (267 aa)
usp13Ubiquitin carboxyl-terminal hydrolase. (842 aa)
Ube3d.SUncharacterized protein. (411 aa)
Tnfaip3.SUncharacterized protein. (781 aa)
trim67Uncharacterized protein. (728 aa)
anapc1APC1_C domain-containing protein. (1948 aa)
Peli2.SUncharacterized protein. (418 aa)
eif3hEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (334 aa)
rnf19a-2RBR-type E3 ubiquitin transferase. (787 aa)
wwp1E3 ubiquitin-protein ligase. (919 aa)
rnf144b-2RBR-type E3 ubiquitin transferase. (303 aa)
ube2ql1-2UBIQUITIN_CONJUGAT_2 domain-containing protein. (324 aa)
otud1OTU domain-containing protein. (319 aa)
Fam188b.LDUF4205 domain-containing protein. (743 aa)
Myc.SMyc_N domain-containing protein. (176 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (334 aa)
rnf19aRBR-type E3 ubiquitin transferase. (787 aa)
ube2v2UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
fbxo15F-box domain-containing protein. (534 aa)
rnf144bRBR-type E3 ubiquitin transferase. (303 aa)
otulinUncharacterized protein. (586 aa)
ube2ql1UBIQUITIN_CONJUGAT_2 domain-containing protein. (323 aa)
uba5ThiF domain-containing protein. (397 aa)
ankib1RBR-type E3 ubiquitin transferase. (1063 aa)
ube2s-2UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
trim28-2Uncharacterized protein. (795 aa)
ube4aU-box domain-containing protein. (1074 aa)
usp2-2Ubiquitin carboxyl-terminal hydrolase. (559 aa)
cblUncharacterized protein. (887 aa)
ube4bU-box domain-containing protein. (1298 aa)
anapc16-2Uncharacterized protein. (144 aa)
bnip3Uncharacterized protein. (196 aa)
stambpl1MPN domain-containing protein. (431 aa)
ube2sUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
trim28Uncharacterized protein. (798 aa)
Ube4a.SU-box domain-containing protein. (1091 aa)
anapc16Uncharacterized protein. (144 aa)
neurl1Uncharacterized protein. (555 aa)
gabarapl1Uncharacterized protein. (117 aa)
A0A1L8FAC5Uncharacterized protein. (419 aa)
Atxn3.LJosephin domain-containing protein. (346 aa)
ubr7UBR-type domain-containing protein. (455 aa)
sae1ThiF domain-containing protein. (344 aa)
ring1RING-type domain-containing protein. (372 aa)
trim32Uncharacterized protein. (649 aa)
cdc26Uncharacterized protein. (84 aa)
anapc2CULLIN_2 domain-containing protein; Belongs to the cullin family. (810 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (285 aa)
Ring1.SRING-type domain-containing protein. (376 aa)
rnf128RING-type domain-containing protein. (400 aa)
URM1Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically [...] (141 aa)
atxn3Josephin domain-containing protein. (354 aa)
Uba1.SUBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1044 aa)
Elob.LUbiquitin-like domain-containing protein. (200 aa)
stub1-2Uncharacterized protein. (309 aa)
Ccnf.LF-box domain-containing protein; Belongs to the cyclin family. (761 aa)
usp7-2Usp7; Belongs to the peptidase C19 family. (1124 aa)
rnf216Uncharacterized protein. (864 aa)
Sumo1.LUbiquitin-like domain-containing protein. (148 aa)
fbxw10WD_REPEATS_REGION domain-containing protein. (1064 aa)
sumo2-2Ubiquitin-like domain-containing protein. (98 aa)
ube2cUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
Ube2v1.LUBIQUITIN_CONJUGAT_2 domain-containing protein. (201 aa)
ube2z-2UBIQUITIN_CONJUGAT_2 domain-containing protein. (313 aa)
dnajc7-2Uncharacterized protein. (493 aa)
stub1Uncharacterized protein. (310 aa)
ube2iUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
usp7Uncharacterized protein; Belongs to the peptidase C19 family. (1123 aa)
Sumo1.SUbiquitin-like domain-containing protein. (141 aa)
wdsub1Uncharacterized protein. (484 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
ube2zUBIQUITIN_CONJUGAT_2 domain-containing protein. (313 aa)
dnajc7Uncharacterized protein. (493 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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