46 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tsc1	Uncharacterized protein. (1104 aa)
	A0A1L8EKN2	Uncharacterized protein. (748 aa)
	pard6b	Uncharacterized protein. (377 aa)
	ntn1	Uncharacterized protein. (602 aa)
	ntn3	Uncharacterized protein. (588 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	ntn1-2	Uncharacterized protein. (602 aa)
	ntn3-2	Uncharacterized protein. (588 aa)
	tsc1-2	Uncharacterized protein. (1102 aa)
	sik2	Uncharacterized protein. (896 aa)
	ntn5	Uncharacterized protein. (601 aa)
	sik2-2	Uncharacterized protein. (901 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (590 aa)
	map4	Microtubule-associated protein. (1211 aa)
	snrk	Uncharacterized protein. (764 aa)
	Map4.L	Microtubule-associated protein. (1234 aa)
	snrk-2	Uncharacterized protein. (764 aa)
	arc	Arc_C domain-containing protein. (383 aa)
	Mark1.S	Non-specific serine/threonine protein kinase. (792 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	mark2	Non-specific serine/threonine protein kinase. (792 aa)
	Rho.L	Rhodopsin. (459 aa)
	sema3a	Uncharacterized protein; Belongs to the semaphorin family. (771 aa)
	pawr	Uncharacterized protein. (349 aa)
	ppp1r12a	Protein phosphatase 1 regulatory subunit. (1022 aa)
	Pawr.L	Uncharacterized protein. (346 aa)
	ppp1r12a-2	Protein phosphatase 1 regulatory subunit. (1022 aa)
	reln	Uncharacterized protein. (3461 aa)
	sema3a-2	Uncharacterized protein; Belongs to the semaphorin family. (774 aa)
	pkn1	Uncharacterized protein. (942 aa)
	sik1	Protein kinase domain-containing protein. (637 aa)
	ngf	NGF domain-containing protein; Belongs to the NGF-beta family. (242 aa)
	Ngf.L	NGF domain-containing protein; Belongs to the NGF-beta family. (232 aa)
	nuak2	Protein kinase domain-containing protein. (570 aa)
	emx1	Homeobox domain-containing protein. (254 aa)
	stk11	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	stk11-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	pten	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	ntn5-2	LOC100127305 protein. (601 aa)
	rac1	MGC114731 protein. (192 aa)
	nuak2-2	LOC495481 protein. (570 aa)
	bdnf-2	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	creb1	Creb1-prov protein. (324 aa)
	rac3	RAC1 protein. (192 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Map4.L	Mark1.S	A0A1L8FUT9	A0A1L8G148	Microtubule-associated protein.	Non-specific serine/threonine protein kinase.	0.436
Map4.L	actl6a	A0A1L8FUT9	Q7ZYI5	Microtubule-associated protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.410
Mark1.S	Map4.L	A0A1L8G148	A0A1L8FUT9	Non-specific serine/threonine protein kinase.	Microtubule-associated protein.	0.436
Mark1.S	Prkci.L	A0A1L8G148	A0A1L8GAK2	Non-specific serine/threonine protein kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.405
Mark1.S	map4	A0A1L8G148	A0A1L8FQC1	Non-specific serine/threonine protein kinase.	Microtubule-associated protein.	0.438
Mark1.S	ppp1r12a	A0A1L8G148	A0A1L8GUG2	Non-specific serine/threonine protein kinase.	Protein phosphatase 1 regulatory subunit.	0.452
Mark1.S	ppp1r12a-2	A0A1L8G148	A0A1L8GYQ0	Non-specific serine/threonine protein kinase.	Protein phosphatase 1 regulatory subunit.	0.452
Ngf.L	ngf	A0A1L8HE07	A0A1L8H693	NGF domain-containing protein; Belongs to the NGF-beta family.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.900
Ngf.L	ntn1	A0A1L8HE07	A0A1L8EN54	NGF domain-containing protein; Belongs to the NGF-beta family.	Uncharacterized protein.	0.438
Ngf.L	ntn1-2	A0A1L8HE07	A0A1L8EV13	NGF domain-containing protein; Belongs to the NGF-beta family.	Uncharacterized protein.	0.437
Ngf.L	ntn3	A0A1L8HE07	A0A1L8EQL7	NGF domain-containing protein; Belongs to the NGF-beta family.	Uncharacterized protein.	0.438
Ngf.L	ntn3-2	A0A1L8HE07	A0A1L8EY77	NGF domain-containing protein; Belongs to the NGF-beta family.	Uncharacterized protein.	0.438
Ngf.L	ntn5	A0A1L8HE07	A0A1L8FGS1	NGF domain-containing protein; Belongs to the NGF-beta family.	Uncharacterized protein.	0.437
Ngf.L	ntn5-2	A0A1L8HE07	A9JS48	NGF domain-containing protein; Belongs to the NGF-beta family.	LOC100127305 protein.	0.437
Pawr.L	pard6b	A0A1L8GYL5	A0A1L8ELH2	Uncharacterized protein.	Uncharacterized protein.	0.470
Pawr.L	pard6b-2	A0A1L8GYL5	A0A1L8ESP6	Uncharacterized protein.	Uncharacterized protein.	0.470
Prkci.L	Mark1.S	A0A1L8GAK2	A0A1L8G148	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Non-specific serine/threonine protein kinase.	0.405
Prkci.L	Rho.L	A0A1L8GAK2	A0A1L8GPJ9	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Rhodopsin.	0.427
Prkci.L	actl6a	A0A1L8GAK2	Q7ZYI5	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Baf53a-pending-prov protein; Belongs to the actin family.	0.768
Prkci.L	pard6b	A0A1L8GAK2	A0A1L8ELH2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.999