(19 nodes) (2022) Arterial Blood Pressure, Neuronal Excitability, Mineral Metabolism and Cell Volume Regulation Mechanisms Revealed by Xenopus laevis oocytes. network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	slc12a2	Uncharacterized protein. (1142 aa)
	slc12a2-2	Uncharacterized protein. (1158 aa)
	oxsr1	Stk39 protein. (528 aa)
	kcnj1-2	MGC86330 protein. (372 aa)
	stk24-2	MGC80614 protein. (424 aa)
	wnk4	Protein kinase domain-containing protein. (1573 aa)
	wnk4-2	Protein kinase domain-containing protein. (1575 aa)
	slc12a5	Uncharacterized protein. (1100 aa)
	Wnk3.S	Protein kinase domain-containing protein. (2749 aa)
	kcnj1	Uncharacterized protein. (371 aa)
	cul3	CULLIN_2 domain-containing protein; Belongs to the cullin family. (768 aa)
	cul3-2	CULLIN_2 domain-containing protein; Belongs to the cullin family. (768 aa)
	Wnk1.S	Uncharacterized protein. (265 aa)
	slc12a1	Uncharacterized protein. (1086 aa)
	A0A1L8H5K9	G_PROTEIN_RECEP_F3_4 domain-containing protein. (1045 aa)
	Atp1a1.S	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1106 aa)
	stk24	Protein kinase domain-containing protein. (425 aa)
	atp1a1	Sodium/potassium-transporting ATPase subunit alpha. (1025 aa)
	slc12a4	Uncharacterized protein. (1133 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8H5K9	kcnj1	A0A1L8H5K9	A0A1L8FFR6	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Uncharacterized protein.	0.624
A0A1L8H5K9	kcnj1-2	A0A1L8H5K9	Q6AX29	G_PROTEIN_RECEP_F3_4 domain-containing protein.	MGC86330 protein.	0.623
A0A1L8H5K9	slc12a1	A0A1L8H5K9	A0A1L8H0K3	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Uncharacterized protein.	0.489
Atp1a1.S	kcnj1	A0A1L8H5S3	A0A1L8FFR6	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Uncharacterized protein.	0.478
Atp1a1.S	kcnj1-2	A0A1L8H5S3	Q6AX29	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	MGC86330 protein.	0.478
Atp1a1.S	slc12a1	A0A1L8H5S3	A0A1L8H0K3	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Uncharacterized protein.	0.767
Atp1a1.S	slc12a2	A0A1L8H5S3	A0A1L8HQZ9	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Uncharacterized protein.	0.809
Atp1a1.S	slc12a2-2	A0A1L8H5S3	A0A1L8I1I1	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Uncharacterized protein.	0.809
Atp1a1.S	slc12a4	A0A1L8H5S3	A0A1L8HZL0	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Uncharacterized protein.	0.638
Atp1a1.S	slc12a5	A0A1L8H5S3	A0A1L8ETT5	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Uncharacterized protein.	0.569
Wnk1.S	Wnk3.S	A0A1L8GQQ4	A0A1L8F1U7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.693
Wnk1.S	cul3	A0A1L8GQQ4	A0A1L8G4G3	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.839
Wnk1.S	cul3-2	A0A1L8GQQ4	A0A1L8GAJ9	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.839
Wnk1.S	kcnj1	A0A1L8GQQ4	A0A1L8FFR6	Uncharacterized protein.	Uncharacterized protein.	0.895
Wnk1.S	kcnj1-2	A0A1L8GQQ4	Q6AX29	Uncharacterized protein.	MGC86330 protein.	0.895
Wnk1.S	oxsr1	A0A1L8GQQ4	A0JPG0	Uncharacterized protein.	Stk39 protein.	0.978
Wnk1.S	slc12a1	A0A1L8GQQ4	A0A1L8H0K3	Uncharacterized protein.	Uncharacterized protein.	0.912
Wnk1.S	slc12a2	A0A1L8GQQ4	A0A1L8HQZ9	Uncharacterized protein.	Uncharacterized protein.	0.915
Wnk1.S	slc12a2-2	A0A1L8GQQ4	A0A1L8I1I1	Uncharacterized protein.	Uncharacterized protein.	0.915
Wnk1.S	slc12a4	A0A1L8GQQ4	A0A1L8HZL0	Uncharacterized protein.	Uncharacterized protein.	0.901