24 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	pard3	Uncharacterized protein. (1369 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	add3	Aldolase_II domain-containing protein. (689 aa)
	notch1	Uncharacterized protein. (2521 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	Camsap1.S	Uncharacterized protein. (1576 aa)
	Pcnt.L	PACT_coil_coil domain-containing protein. (4481 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	pard6b	Uncharacterized protein. (377 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	add3-2	LOC432146 protein. (687 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	ddx4	DEAD box protein; Belongs to the DEAD box helicase family. (700 aa)
	fst-2	Uncharacterized protein. (341 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	add1-2	Aldolase_II domain-containing protein. (843 aa)
	fst	Uncharacterized protein. (339 aa)
	add2-2	Aldolase_II domain-containing protein. (717 aa)
	Cpeb1.L	Uncharacterized protein. (568 aa)
	cpeb1	Uncharacterized protein. (568 aa)
	add2	Aldolase_II domain-containing protein. (721 aa)
	Cdkn1b.S	Uncharacterized protein. (152 aa)
	pard3-2	Uncharacterized protein. (1332 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FND1	Cdkn1b.S	A0A1L8FND1	A0A1L8GQW1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.433
A0A1L8FND1	Egf.L	A0A1L8FND1	A0A1L8HUT3	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.962
A0A1L8FND1	Notch1.S	A0A1L8FND1	A0A1L8F124	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.589
A0A1L8FND1	actl6a	A0A1L8FND1	Q7ZYI5	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Baf53a-pending-prov protein; Belongs to the actin family.	0.733
A0A1L8FND1	ins	A0A1L8FND1	A0A1L8GD41	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.907
A0A1L8FND1	ins-2	A0A1L8FND1	B7ZQP1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.905
A0A1L8FND1	notch1	A0A1L8FND1	A0A1L8F627	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.589
Cdkn1b.S	A0A1L8FND1	A0A1L8GQW1	A0A1L8FND1	Uncharacterized protein.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.433
Cdkn1b.S	Notch1.S	A0A1L8GQW1	A0A1L8F124	Uncharacterized protein.	Uncharacterized protein.	0.483
Cdkn1b.S	actl6a	A0A1L8GQW1	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.436
Cdkn1b.S	ins	A0A1L8GQW1	A0A1L8GD41	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.432
Cdkn1b.S	ins-2	A0A1L8GQW1	B7ZQP1	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.403
Cdkn1b.S	notch1	A0A1L8GQW1	A0A1L8F627	Uncharacterized protein.	Uncharacterized protein.	0.484
Egf.L	A0A1L8FND1	A0A1L8HUT3	A0A1L8FND1	Uncharacterized protein.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.962
Egf.L	Notch1.S	A0A1L8HUT3	A0A1L8F124	Uncharacterized protein.	Uncharacterized protein.	0.415
Egf.L	actl6a	A0A1L8HUT3	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.636
Egf.L	fst	A0A1L8HUT3	A0A1L8HRM9	Uncharacterized protein.	Uncharacterized protein.	0.486
Egf.L	fst-2	A0A1L8HUT3	A0A1L8I2C7	Uncharacterized protein.	Uncharacterized protein.	0.485
Egf.L	ins	A0A1L8HUT3	A0A1L8GD41	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.961
Egf.L	ins-2	A0A1L8HUT3	B7ZQP1	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.961