45 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	rac1	MGC114731 protein. (192 aa)
	Cfl2.S	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
	kif26a	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1983 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	Pak3.L	Non-specific serine/threonine protein kinase. (564 aa)
	fmr1	Uncharacterized protein. (564 aa)
	Arhgef2.S	Uncharacterized protein. (1003 aa)
	notch1	Uncharacterized protein. (2521 aa)
	kif26a-2	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1993 aa)
	cfl2	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
	arhgef2	Uncharacterized protein. (984 aa)
	Zeb1.S	Uncharacterized protein. (919 aa)
	A0A1L8G7I3	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	cfl1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
	Cfl1.L	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	Rho.L	Rhodopsin. (459 aa)
	neurog1	BHLH domain-containing protein. (229 aa)
	pkn1	Uncharacterized protein. (942 aa)
	cdkl5	Protein kinase domain-containing protein. (1019 aa)
	nck2	Cytoplasmic protein. (381 aa)
	arhgef7	Uncharacterized protein. (818 aa)
	Git1	Uncharacterized protein. (737 aa)
	cdkl5-2	Protein kinase domain-containing protein. (1020 aa)
	cdkn1a	Uncharacterized protein. (261 aa)
	nf1	Uncharacterized protein. (2759 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	arhgef7-2	Uncharacterized protein. (802 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	ctbp1	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa)
	A0A1L8HTA9	Uncharacterized protein. (3120 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	nck1	Cytoplasmic protein. (377 aa)
	dstn	MGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	fmr1-A	Fragile X mental retardation 1. (564 aa)
	pak3	Non-specific serine/threonine protein kinase. (549 aa)
	pxn	Uncharacterized protein; Belongs to the paxillin family. (542 aa)
	rac3	RAC1 protein. (192 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	pxn-2	LOC397826 protein; Belongs to the paxillin family. (539 aa)
	creb1	Creb1-prov protein. (324 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	grb2	Uncharacterized protein. (229 aa)
	grb2-2	Uncharacterized protein. (229 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8G7I3	Cfl1.L	A0A1L8G7I3	A0A1L8GJZ1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.408
A0A1L8G7I3	Rho.L	A0A1L8G7I3	A0A1L8GPJ9	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Rhodopsin.	0.677
A0A1L8G7I3	actl6a	A0A1L8G7I3	Q7ZYI5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.992
A0A1L8G7I3	creb1	A0A1L8G7I3	Q8AVY5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Creb1-prov protein.	0.431
A0A1L8G7I3	fmr1	A0A1L8G7I3	A0A1L8F2W4	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.400
A0A1L8G7I3	fmr1-A	A0A1L8G7I3	B7ZRL0	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Fragile X mental retardation 1.	0.402
A0A1L8G7I3	nck1	A0A1L8G7I3	P79956	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Cytoplasmic protein.	0.426
A0A1L8G7I3	nck1-2	A0A1L8G7I3	Q32NQ4	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Cytoplasmic protein.	0.426
A0A1L8G7I3	pkn1	A0A1L8G7I3	A0A1L8H2L2	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.541
A0A1L8G7I3	pxn	A0A1L8G7I3	A0A1L8I058	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein; Belongs to the paxillin family.	0.566
A0A1L8G7I3	pxn-2	A0A1L8G7I3	Q9I957	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	LOC397826 protein; Belongs to the paxillin family.	0.566
A0A1L8G7I3	rac1	A0A1L8G7I3	Q58E25	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	MGC114731 protein.	0.826
A0A1L8G7I3	rac3	A0A1L8G7I3	Q9PW31	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	RAC1 protein.	0.641
A0A1L8HTA9	Casp3.L	A0A1L8HTA9	A0A1L8HU08	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.436
A0A1L8HTA9	Jun.L	A0A1L8HTA9	A0A1L8GLZ4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.403
A0A1L8HTA9	Pak3.L	A0A1L8HTA9	A0A1L8F2P5	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.440
A0A1L8HTA9	actl6a	A0A1L8HTA9	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.460
A0A1L8HTA9	c-Jun	A0A1L8HTA9	Q9PVZ1	Uncharacterized protein.	C-Jun protein; Belongs to the bZIP family.	0.403
A0A1L8HTA9	casp3.2	A0A1L8HTA9	A0A1L8HLJ6	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.436
A0A1L8HTA9	creb1	A0A1L8HTA9	Q8AVY5	Uncharacterized protein.	Creb1-prov protein.	0.682