(33 nodes) (2023) MAP4Ks inhibition promotes retinal neuron regeneration from Muller glia in adult mice. network (Xenopus laevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mink1	Misshapen/Nck interacting Kinase. (1270 aa)
	rcvrn.2	MGC84117 protein. (192 aa)
	sox9-a	Sex determining region Y-box 9. (477 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	atoh7	Atonal homolog 5a. (138 aa)
	slc1a3	Amino acid transporter. (592 aa)
	gne	Epimerase_2 domain-containing protein. (796 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	atoh1-2	BHLH domain-containing protein. (256 aa)
	Arrb2.L	Arrestin_C domain-containing protein. (446 aa)
	Ascl1.L	BHLH domain-containing protein. (242 aa)
	Opsin	Rhodopsin. (403 aa)
	Rho.L	Rhodopsin. (459 aa)
	calb2-2	Uncharacterized protein. (272 aa)
	pax6-2	Uncharacterized protein. (467 aa)
	A0A1L8GHL0	Rhodopsin. (354 aa)
	calb2	Uncharacterized protein. (272 aa)
	tead1	TEA domain-containing protein. (447 aa)
	pax6	Uncharacterized protein. (467 aa)
	tnik	Uncharacterized protein. (1326 aa)
	Lats1.S	Uncharacterized protein. (1118 aa)
	glul	Glutamine synthetase. (392 aa)
	glul-2	Glutamine synthetase. (371 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	ptbp1	Ptbp1 protein. (547 aa)
	A0A1L8F0T8	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (369 aa)
	A0A1L8EUU9	Uncharacterized protein. (202 aa)
	Gad1.1.S	Uncharacterized protein. (563 aa)
	A0A1L8EN80	Uncharacterized protein. (202 aa)
	atoh1	Atonal 1. (263 aa)
	glul-like.1	Glutamine synthetase. (373 aa)
	MGC80056	Glutamine synthetase. (373 aa)
	rcvrn.2-2	MGC84424 protein. (192 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EN80	A0A1L8F0T8	A0A1L8EN80	A0A1L8F0T8	Uncharacterized protein.	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	0.596
A0A1L8EN80	A0A1L8GHL0	A0A1L8EN80	A0A1L8GHL0	Uncharacterized protein.	Rhodopsin.	0.956
A0A1L8EN80	Arrb2.L	A0A1L8EN80	A0A1L8H368	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.844
A0A1L8EN80	Gad1.1.S	A0A1L8EN80	A0A1L8EPB0	Uncharacterized protein.	Uncharacterized protein.	0.411
A0A1L8EN80	MGC80056	A0A1L8EN80	Q6INY0	Uncharacterized protein.	Glutamine synthetase.	0.596
A0A1L8EN80	Opsin	A0A1L8EN80	A0A1L8GPM0	Uncharacterized protein.	Rhodopsin.	0.957
A0A1L8EN80	Rho.L	A0A1L8EN80	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.934
A0A1L8EN80	atoh7	A0A1L8EN80	B7ZQX7	Uncharacterized protein.	Atonal homolog 5a.	0.455
A0A1L8EN80	calb2	A0A1L8EN80	A0A1L8GF11	Uncharacterized protein.	Uncharacterized protein.	0.669
A0A1L8EN80	calb2-2	A0A1L8EN80	A0A1L8GLF3	Uncharacterized protein.	Uncharacterized protein.	0.669
A0A1L8EN80	glul	A0A1L8EN80	A0A1L8F5W7	Uncharacterized protein.	Glutamine synthetase.	0.580
A0A1L8EN80	glul-2	A0A1L8EN80	Q7M567	Uncharacterized protein.	Glutamine synthetase.	0.580
A0A1L8EN80	glul-like.1	A0A1L8EN80	Q7SZ38	Uncharacterized protein.	Glutamine synthetase.	0.582
A0A1L8EN80	pax6	A0A1L8EN80	A0A1L8GDT8	Uncharacterized protein.	Uncharacterized protein.	0.700
A0A1L8EN80	pax6-2	A0A1L8EN80	A0A1L8GJ29	Uncharacterized protein.	Uncharacterized protein.	0.699
A0A1L8EUU9	A0A1L8F0T8	A0A1L8EUU9	A0A1L8F0T8	Uncharacterized protein.	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	0.596
A0A1L8EUU9	A0A1L8GHL0	A0A1L8EUU9	A0A1L8GHL0	Uncharacterized protein.	Rhodopsin.	0.956
A0A1L8EUU9	Arrb2.L	A0A1L8EUU9	A0A1L8H368	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.844
A0A1L8EUU9	Gad1.1.S	A0A1L8EUU9	A0A1L8EPB0	Uncharacterized protein.	Uncharacterized protein.	0.411
A0A1L8EUU9	MGC80056	A0A1L8EUU9	Q6INY0	Uncharacterized protein.	Glutamine synthetase.	0.596