35 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kit.L	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	gpc4-2	Xgly4 protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	tbxt-2	MGC81453 protein. (432 aa)
	rhoa	MGC64296 protein. (193 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	sp8-2	Uncharacterized protein. (500 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
	tbxt	Uncharacterized protein. (432 aa)
	gpc1	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (552 aa)
	gpc1-2	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (552 aa)
	ryk	Uncharacterized protein. (596 aa)
	pax6-2	Uncharacterized protein. (467 aa)
	Ctrl.L	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
	wasl	Uncharacterized protein. (509 aa)
	Wasl.L	Uncharacterized protein. (509 aa)
	Kit.S	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	bcr	Uncharacterized protein. (1160 aa)
	Bcr.L	Uncharacterized protein. (1180 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	rab5c	Uncharacterized protein. (215 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	gpc4	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (549 aa)
	vangl2	Vang-like protein. (521 aa)
	vangl2-2	Vang-like protein. (521 aa)
	sp8	Uncharacterized protein. (513 aa)
	Rab5a.L	Uncharacterized protein. (216 aa)
	Fzd6.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bcr.L	rhoa	A0A1L8I0D0	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.440
Ctrl.L	actl6a	A0A1L8GK48	Q7ZYI5	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.518
Fzd6.S	Fzd8.L	A0A1L8FTP5	A0A1L8FVD0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.472
Fzd6.S	actl6a	A0A1L8FTP5	Q7ZYI5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.423
Fzd6.S	ctnnb1	A0A1L8FTP5	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.803
Fzd6.S	fzd5	A0A1L8FTP5	A0A1L8EPX2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.474
Fzd6.S	fzd7	A0A1L8FTP5	A0A1L8EX17	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.450
Fzd6.S	gpc4	A0A1L8FTP5	A0A1L8F395	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.717
Fzd6.S	gpc4-2	A0A1L8FTP5	Q5EAV3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Xgly4 protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.717
Fzd6.S	lef1	A0A1L8FTP5	A0A1L8HM07	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	HMG box domain-containing protein.	0.402
Fzd6.S	lef1-2	A0A1L8FTP5	Q90ZB8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Lymphoid enhancer factor XLEF-1.	0.404
Fzd6.S	rhoa	A0A1L8FTP5	Q7SZA9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	MGC64296 protein.	0.408
Fzd6.S	ror2	A0A1L8FTP5	A0A1L8HPI6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.865
Fzd6.S	ror2-2	A0A1L8FTP5	Q8AV69	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.865
Fzd6.S	ryk	A0A1L8FTP5	A0A1L8GB75	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.859
Fzd6.S	vangl2	A0A1L8FTP5	A0A1L8F4R0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Vang-like protein.	0.940
Fzd6.S	vangl2-2	A0A1L8FTP5	A0A1L8FCL1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Vang-like protein.	0.940
Fzd6.S	wnt3a	A0A1L8FTP5	A0A1L8FUX8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.926
Fzd6.S	xfz8	A0A1L8FTP5	B7ZQV9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.476
Fzd8.L	Fzd6.S	A0A1L8FVD0	A0A1L8FTP5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.472